Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Anna D. Kosinska"'
Autor:
Sophia Schreiber, Lisa S. Dressler, Eva Loffredo-Verde, Theresa Asen, Stephanie Färber, Wenshi Wang, Tanja Groll, Anindita Chakraborty, Fenna Kolbe, Christoph Kreer, Anna D. Kosinska, Sylvain Simon, Stephan Urban, Florian Klein, Stanley R. Riddell, Ulrike Protzer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
To design new CARs targeting hepatitis B virus (HBV), we isolated human monoclonal antibodies recognizing the HBV envelope proteins from single B cells of a patient with a resolved infection. HBV-specific memory B cells were isolated by incubating pe
Externí odkaz:
https://doaj.org/article/fdca145596494b01b5da3bfa491a5454
Autor:
Jinpeng Su, Zahra Harati Taji, Anna D. Kosinska, Edanur Ates Oz, Zhe Xie, Pavlo Bielytskyi, Mikhail Shein, Philipp Hagen, Shohreh Esmaeili, Katja Steiger, Ulrike Protzer, Anne K. Schütz
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 100997- (2024)
Background & Aims: Particulate hepatitis B core antigen (HBcoreAg) is a potent immunogen used as a vaccine carrier platform. HBcoreAg produced in E. coli encapsidates random bacterial RNA (bRNA). Using the heterologous protein-prime, viral-vector-boo
Externí odkaz:
https://doaj.org/article/f0879e7c303e4f3bbb4b61d82f789e2c
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/b82d6e72d70d4818aa272cdf8b3b7d02
Autor:
Ann-Sophie Stephan, Anna D. Kosinska, Martin Mück-Häusl, Andreas Muschaweckh, Clemens Jäger, Natalie Röder, Mathias Heikenwälder, Claudia Dembek, Ulrike Protzer
Publikováno v:
Vaccines, Vol 11, Iss 2, p 245 (2023)
Here, we investigate the potential of CD70 co-expression during viral vector boost vaccination to improve an antigen-specific T cell response. To determine the chance of activating antigen-specific T cells by CD70, we used the HBV core antigen as a m
Externí odkaz:
https://doaj.org/article/4b8c691982e649e98dd5bc6e1147d738
Autor:
Alexandre Klopp, Sophia Schreiber, Anna D. Kosinska, Martin Pulé, Ulrike Protzer, Karin Wisskirchen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T-cell therapy with T cells that are re-directed to hepatitis B virus (HBV)-infected cells by virus-specific receptors is a promising therapeutic approach for treatment of chronic hepatitis B and HBV-associated cancer. Due to the high number of targe
Externí odkaz:
https://doaj.org/article/963532d766764465999c08c6caa31340
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 470 (2022)
In chronic hepatitis B virus (HBV) infection, virus-specific T cells are scarce and partially dysfunctional. Therapeutic vaccination is a promising strategy to induce and activate new virus-specific T cells. In long-term or high-level HBV carriers, h
Externí odkaz:
https://doaj.org/article/194404620b284894a543e242a009aa9c
Autor:
Anna D. Kosinska, Julia Festag, Martin Mück-Häusl, Marvin M. Festag, Theresa Asen, Ulrike Protzer
Publikováno v:
Vaccines, Vol 9, Iss 8, p 841 (2021)
During the natural course of chronic hepatitis B virus (HBV) infection, the hepatitis B e antigen (HBeAg) is typically lost, while the direct transmission of HBeAg-negative HBV may result in fulminant hepatitis B. While the induction of HBV-specific
Externí odkaz:
https://doaj.org/article/dc9a743435d84480aae519ae7734b9fc
Autor:
Ann-Sophie Stephan, Anna D. Kosinska, Martin Mück-Häusl, Andreas Muschaweckh, Clemens Jäger, Natalie Röder, Mathias Heikenwälder, Claudia Dembek, Ulrike Protzer
Publikováno v:
Vaccines
Volume 11
Issue 2
Pages: 245
Volume 11
Issue 2
Pages: 245
Here, we investigate the potential of CD70 co-expression during viral vector boost vaccination to improve an antigen-specific T cell response. To determine the chance of activating antigen-specific T cells by CD70, we used the HBV core antigen as a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b642772f634dadc65bbba114ea45aa
https://mediatum.ub.tum.de/1701689
https://mediatum.ub.tum.de/1701689
Autor:
Julia Sacherl, Anna D. Kosinska, Kristina Kemter, Martin Kächele, Sabine C. Laumen, Hélène A. Kerth, Edanur Ates Öz, Lisa S. Wolff, Jinpeng Su, Sandra Essbauer, Gerd Sutter, Martin Scholz, Katrin Singethan, Jens Altrichter, Ulrike Protzer
Publikováno v:
JHEP Reports. 5:100603
Publikováno v:
Vaccines
Vaccines, Vol 9, Iss 1333, p 1333 (2021)
Vaccines, Vol 9, Iss 1333, p 1333 (2021)
Chronic hepatitis B affects more than 250 million individuals worldwide, putting them at risk of developing liver cirrhosis and liver cancer. While antiviral immune responses are key to eliminating hepatitis B virus (HBV) infections, insufficient ant