I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations

Autor: Carolyn S Calfee, Michael A Matthay, Paul Henderson, Martin Eklund, Laura J Esserman, Chirag Patel, Angela Haczku, Michelle Jung, Tony Oliver, Alessio Crippa, Andrea Discacciati, Kathleen D Liu, Ellen L Burnham, Nuala J Meyer, Fady A Youssef, Derek W Russell, Julie Lang, Kevin W Gibbs, Daniel C Files, Sheetal Gandotra, Purnema Madahar, Nathan K Cobb, Timothy E Albertson, Rajiv Sonti, John P Reilly, Alejandra Jauregui, Iván García, Luis E Huerta, Daniel Clark Files, Neil R Aggarwal, Adam L Asare, Jeremy R Beitler, Paul A Berger, George Cimino, Melissa H Coleman, Paul T Henderson, Caroline A G Ittner, Kashif T Khan, Jonathan L Koff, Mary LaRose, Joe Levitt, Ruixiao Lu, Jeffrey D McKeehan, Karl W Thomas, Aaron M Mittel, Albert F Yen, Alexis E Suarez, Alexis L Serra, Alpesh N Amin, Amanda Rosen, Amy L Dzierba, Anna D Barker, Ariel R Weisman, Brian M Daniel, Brian M Morrissey, Caroline AG Ittner, Chayse Jones, Christina Creel-Bulos, Christina M Angelucci, Diana Ng, Fredy Chaparro-Rojas, Gavin H Harris, Harsh V Barot, Heny Su, Jacqueline B Sutter, Jamal Dodin, Jerry S Lee, John Kazianis, Joshua F Detelich, Julie E Lang, Justin Muir, Katarzyna Gosek, Katherine L Nugent, Kimberly Yee, Laura G Rodrigues, Laura R Macias, Lindsey A Orr, Lindsie L Boerger, Lissette Rosario-Remigio, Lucia Kufa, Maged Tanios, Maria B Reyes, Max W Adelman, Maya M Juarez, Michelle Meyers, Mitchell P Sternlieb, Neil Aggarwal, Nilam S Mangalmurti, Patrice Jones, Paul L Saban, Peter S Marshall, Philiip A Robinson, Philip Yang, Rahul Nair, Richard Anthony Lee, Richard G Wunderink, Romina Wahab, Roxana A Lupu, Santhi I Kumar, Sara C Auld, Scott Fields, Se Fum Wong, Skyler J Pearson, Spencer Whealon, Timothy F Obermiller, Anita Darmanian, John Schicchi, Esmeralda Martinez, Farjad Sarafian, Julie Nguyen, Bethany Weiler-Lisowski, Jaime Wyatt, Daniel Blevins, Marylee Melendrez, Brenda Lopez, Hiwet Tzehaie, Omowunmi Amosu, Austin Simonson, Erin Hardy, Brett Lindgren, Gregory Peterfreund, Leigha Landreth, Lisa Parks

Publikováno v: BMJ Open, Vol 12, Iss 6 (2022)

Externí odkaz: https://doaj.org/article/480eafc2c901401aa40873075dcf1eb8

An Inflection Point in Cancer Protein Biomarkers: What Was and What’s Next

Autor: Anna D. Barker, Mario M. Alba, Parag Mallick, David B. Agus, Jerry S.H. Lee

Publikováno v: Molecular & Cellular Proteomics. :100569

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::232ab8bfb62b40b5de3fc5131e4523b7
https://doi.org/10.1016/j.mcpro.2023.100569

Abstract P2-09-09: Polyligand profiling differentiates cancer patients according to their benefit of treatment

Autor: George Poste, Simon Peter Gampenrieder, Gabriel Rinnerthaler, Miglarese, Adam Stark, Xixi Wei, A. Voss, John Quackenbush, Valeriy Domenyuk, Anna D. Barker, Nick Xiao, R Wang, Michael Famulok, Richard Greil, John L. Marshall, Lee S. Schwartzberg, DD Halbert, Günter Mayer, B Toussaint, David Spetzler, Gregory A. Vidal, DJ Berry, George D. Demetri, Zoran Gatalica, Symon Levenberg, Radhika Santhanam, J Vacirca, Patrick T F Kennedy, Amy B. Heimberger

Publikováno v: Cancer Research. 78:P2-09

Introduction: Deconvolution of multi-nodal perturbations in cancer network architecture demands highly multiplexed profiling assays. We demonstrate the value of polyligand profiling of tumor systems states using libraries of single stranded oligodeox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26eb354a44669a022508cfee15195321
https://doi.org/10.1158/1538-7445.sabcs17-p2-09-09

Future cancer research priorities in the USA: a Lancet Oncology Commission

Autor: Dean Ornish, Deborah K. Mayer, Richard Sullivan, Andrew Futreal, Alan Ashworth, Brian D. Kavanagh, Richard L. Wahl, Kelly M. McMasters, Chanita Hughes-Halbert, Timothy M. Pawlik, Rick A. Kittles, James R. Heath, Anna D. Barker, Hossein Jadvar, Stanton L. Gerson, Kenneth C. Anderson, SS Gambhir, Daniel G. Coit, Patricia A. Ganz, Elaine R. Mardis, Sandra L. Wong, Ramy Ibrahim, Brian M. Alexander, Atul J. Butte, Ruth I. Hoffman, Peter Naredi, Cliff Hudis, Christine S. Ritchie, Quynh-Thu Le, Jeffrey Peppercorn, Elizabeth M. Jaffee, Mark M. Davis, Beverly S. Mitchell, Robert B. Diasio, David A. Mankoff, Jeffrey A. Bluestone, David B. Agus, Levi A. Garraway, Sangeeta N. Bhatia, A. Lindsay Frazier, Otis W. Brawley, Nancy E. Davidson, Roshan Bastani, Scott M. Lippman, Alfred Yung, Sally W. Schwarz, Martin G. Pomper, Sumit Gupta, Ronald A. DePinho, Neal J. Meropol, Derek Raghavan, Chi Van Dang, Giulio Draetta, Jedd D. Wolchok

Publikováno v: The Lancet. Oncology, vol 18, iss 11

We are in the midst of a technological revolution that is providing new insights into human biology and cancer. In this era of big data, we are amassing large amounts of information that is transforming how we approach cancer treatment and prevention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8ff1fb9e3865740a9d4cfb767b8285
https://pubmed.ncbi.nlm.nih.gov/29208380

Turning the Tide Against Cancer Through Sustained Medical Innovation: The Pathway to Progress

Autor: Anna D. Barker, Zeba M. Khan, Margaret Foti, Felix W. Frueh, Richard B. Gaynor, Amy P. Abernethy, Edward Abrahams, Tracy Lessor, Kenneth H. Buetow, Laura J. van't Veer, Randy Burkholder, John Mendelsohn, Marcia A. Kean, J. Leonard Lichtenfeld, William S. Dalton

Publikováno v: Clinical Cancer Research. 20:1081-1086

An ever-expanding understanding of the molecular basis of the more than 200 unique diseases collectively called cancer, combined with efforts to apply these insights to clinical care, is forming the foundation of an era of personalized medicine that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e7633218f1ea37578c25deaadd63f6
https://doi.org/10.1158/1078-0432.ccr-13-3430