Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anna Cierpich"'
Autor:
Charles-Henry Fabritius, Paulina Węgrzyn, Agata Stasiowska, Marta Bugaj, Andrzej Mazan, Monika Dobrzańska, Karolina Gluza, Piotr Kowalczyk, Ewa Kolasińska, Adrian Zarebski, Przemyslaw Zawadzki, Karolina Krawczynska, Aneta Bobowska, Anna Cierpich, Małgorzata Żurawska, Nicolas Boutard, Mariusz Milik, Katarzyna Wiklik, Anna Buda, Małgorzata Jarosz, Krzysztof Brzózka, Aleksandra Sabiniarz, Mariusz Galek, Edyta Palacz, Klaudia Czerwińska, Claude Commandeur
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:607-613
Maternal embryonic leucine zipper kinase (MELK) is involved in several key cellular processes and displays increased levels of expression in numerous cancer classes (colon, breast, brain, ovary, prostate and lung). Although no selective MELK inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0811d2cb5e37f7797b44a0953a2ff63
https://doi.org/10.1016/j.bmcl.2018.12.051
https://doi.org/10.1016/j.bmcl.2018.12.051
Autor:
Krzysztof Brzózka, Alan P. Watt, Michal Galezowski, Magdalena Mroczkowska, Stefan Chmielewski, Grzegorz Witold Topolnicki, Christopher A. Gabel, David J. Schultz, John R. Doedens, Charles-Henry Fabritius, Oleksandr Levenets, Piotr Kowalczyk, Piotr Urbanski, Katarzyna Palica, Nicolas Boutard, Anna Cierpich, Roderick A. Porter, Marta Bugaj, Jakub Woyciechowski, Marta Sowinska, David G. Harrison
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(23)
The NLRP3 inflammasome is a component of the innate immune system involved in the production of proinflammatory cytokines. Aberrant activation by a wide range of exogenous and endogenous signals can lead to chronic, low-grade inflammation. It has att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9b9567b37c2ffb77ffeec192329547
https://pubmed.ncbi.nlm.nih.gov/32956781
https://pubmed.ncbi.nlm.nih.gov/32956781
Autor:
Nicolas Boutard, Arkadiusz Białas, Aleksandra Sabiniarz, Paweł Guzik, Katarzyna Banaszak, Artur Biela, Marcin Bień, Anna Buda, Barbara Bugaj, Ewelina Cieluch, Anna Cierpich, Łukasz Dudek, Hans-Michael Eggenweiler, Joanna Fogt, Monika Gaik, Andrzej Gondela, Krzysztof Jakubiec, Mirek Jurzak, Agata Kitlińska, Piotr Kowalczyk, Maciej Kujawa, Katarzyna Kwiecińska, Marcin Leś, Ralph Lindemann, Monika Maciuszek, Maciej Mikulski, Paulina Niedziejko, Alicja Obara, Henryk Pawlik, Tomasz Rzymski, Magdalena Sieprawska-Lupa, Marta Sowińska, Joanna Szeremeta-Spisak, Agata Stachowicz, Mateusz M. Tomczyk, Katarzyna Wiklik, Łukasz Włoszczak, Sylwia Ziemiańska, Adrian Zarębski, Krzysztof Brzózka, Mateusz Nowak, Charles-Henry Fabritius
In oncology, the "Warburg effect" describes the elevated production of energy by glycolysis in cancer cells. The ubiquitous and hypoxia-induced 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) plays a noteworthy role in the regulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef37f4c1c80edce81f72f55d3f7931e
https://ruj.uj.edu.pl/xmlui/handle/item/252764
https://ruj.uj.edu.pl/xmlui/handle/item/252764
Autor:
K. Banaszak, M. Gaik, M. Maciuszek, A. Gondela, A. Stachowicz, A. Bialas, A. Kitlinska, K. Kwiecinska, H.M. Eggenweiler, M. Bien, L. Wloszczak, Mateusz Michał Tomczyk, P. Guzik, Magdalena Sieprawska-Lupa, Piotr Kowalczyk, M. Jurzak, Marta Sowinska, M. Les, Mateusz Nowak, Aleksandra Sabiniarz, S. Ziemianska, B. Bugaj, Maciej Mikulski, Nicolas Boutard, L. Dudek, Anna Cierpich, A. Biela, R. Lindemann, Adrian Zarebski, H. Pawlik, J. Fogt, E. Cieluch, Joanna Szeremeta-Spisak, Krzysztof Brzózka, T. Rzymski, M. Kujawa, K. Jakubiec, C.H. Fabritius, Katarzyna Wiklik, A. Obara, Anna Buda, P. Niedziejko
Publikováno v:
ChemMedChem. 14(1)
Energy and biomass production in cancer cells are largely supported by aerobic glycolysis in what is called the Warburg effect. The process is regulated by key enzymes, among which phosphofructokinase PFK-2 plays a significant role by producing fruct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4e2e375f345b45513bf24c44f0ee4c
https://pubmed.ncbi.nlm.nih.gov/30378281
https://pubmed.ncbi.nlm.nih.gov/30378281
Autor:
Krzysztof Brzózka, Adrian Zarebski, Mariusz Milik, Agnieszka Dreas, Tomasz Rzymski, Malgorzata Szajewska Skuta, Anna Cierpich, Katarzyna Kucwaj, Charles Fabritius
Publikováno v:
Cancer Research. 73:A49-A49
MNK1 and MNK2 are MAP kinase-interacting kinases involved in regulation of translation. Both kinases phosphorylate translation initiation factor eIF4E on a conserved serine 209. eIF4E can contribute to the oncogenic transformation both in vitro and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2faa68872df242ee1ba4f544e7d5a607
https://doi.org/10.1158/1538-7445.fbcr13-a49
https://doi.org/10.1158/1538-7445.fbcr13-a49