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pro vyhledávání: '"Anna Christina Heroven"'
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 71:1421-1428
In eukaryotes, the removal of nuclear noncoding sequences (pre-mRNA splicing) is catalyzed by the spliceosome, which consists of five ribonucleoprotein particles (U1, U2, U4, U5 and U6 snRNPs, each with a respective snRNA) and a plethora of protein f
Autor:
Nicole Holton, Jean D. Beggs, Sina Mozaffari Jovin, Markus C. Wahl, Anna Christina Heroven, Karine F. Santos, Vanessa F. Cristão, Gert Weber, Reinhard Lührmann
Publikováno v:
Weber, G, Santos, K F, Heroven, A C, Holton, N, Wahl, M C, Cristão, V F, Beggs, J D, Jovin, S M & Lührmann, R 2013, ' Structural basis for dual roles of Aar2p in U5 snRNP assembly ', Genes & Development, vol. 27, no. 5, pp. 525-540 . https://doi.org/10.1101/gad.213207.113
Genes and Development
Genes and Development
Yeast U5 small nuclear ribonucleoprotein particle (snRNP) is assembled via a cytoplasmic precursor that contains the U5-specific Prp8 protein but lacks the U5-specific Brr2 helicase. Instead, pre-U5 snRNP includes the Aar2 protein not found in mature