Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Anna Celli"'
Publikováno v:
JID Innovations, Vol 2, Iss 2, Pp 100083- (2022)
Epidermal basement membrane, a tightly packed network of extracellular matrix (ECM) components, is a source of physical, chemical, and biological factors required for the structural and functional homeostasis of the epidermis. Variations within the E
Externí odkaz:
https://doaj.org/article/1e47ee71277c48618b69b9f32fafb255
Autor:
Anastasia Petrova, Anna Celli, Laureen Jacquet, Dimitra Dafou, Debra Crumrine, Melanie Hupe, Matthew Arno, Carl Hobbs, Aleksandra Cvoro, Panagiotis Karagiannis, Liani Devito, Richard Sun, Lillian C. Adame, Robert Vaughan, John A. McGrath, Theodora M. Mauro, Dusko Ilic
Publikováno v:
Stem Cell Reports, Vol 2, Iss 5, Pp 675-689 (2014)
Cornification and epidermal barrier defects are associated with a number of clinically diverse skin disorders. However, a suitable in vitro model for studying normal barrier function and barrier defects is still lacking. Here, we demonstrate the gene
Externí odkaz:
https://doaj.org/article/849aec7e6a8540a5aa3d1ac9b310b738
Autor:
Michael C Oh, Joseph M Kim, Michael Safaee, Gurvinder Kaur, Matthew Z Sun, Rajwant Kaur, Anna Celli, Theodora M Mauro, Andrew T Parsa
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47846 (2012)
Glioblastoma multiforme is the most malignant type of primary brain tumor with a poor prognosis. These tumors consist of a heterogeneous population of malignant cells, including well-differentiated tumor cells and less differentiated cells with stem
Externí odkaz:
https://doaj.org/article/7eee35cd2ba0424c861ebcdba17cf8fb
Publikováno v:
J Invest Dermatol
The Ca(2+)-sensing receptor (CaSR) drives essential Ca(2+) and E-cadherin-mediated processes in the epidermis, including differentiation (Komuves et al., 2002), cell-to-cell adhesion (Tu et al., 2008) and epidermal barrier homeostasis in cells and yo
Autor:
Jeanmarie R, Gonzalez, Anna, Celli, Antonin, Weckel, Miqdad O, Dhariwala, Geil R, Merana, Oluwasunmisola T, Ojewumi, Joy, Okoro, Laura R, Dwyer, Victoria M, Tran, Jason M, Meyer, Theodora M, Mauro, Tiffany C, Scharschmidt
Publikováno v:
The Journal of investigative dermatology.
Filaggrin mutations underlie ichthyosis vulgaris and increased risk of atopic dermatitis, conditions typified by disruption of the skin microbiome and cutaneous immune response. Yet, it remains unclear if neonatal skin barrier compromise due to filag
Autor:
Jeanmarie R. Gonzalez, Anna Celli, Antonin Weckel, Miqdad O. Dhariwala, Geil R. Merana, Oluwasunmisola T. Ojewumi, Joy Okoro, Laura R. Dwyer, Victoria M. Tran, Jason M. Meyer, Theodora M. Mauro, Tiffany C. Scharschmidt
Publikováno v:
Journal of Investigative Dermatology. 143:790-800.e12
Autor:
Jakob Jeriha, Preeti Khurana, Theodora M. Mauro, Mitch Gordon, Dusko Ilic, Anna Celli, Nikola Kolundzic
Publikováno v:
Experimental Dermatology. 29:1238-1242
Differentiation of normal human keratinocytes (NHK) grown in vitro as a monolayer to confluency can be triggered with an acute increase in concentration of extracellular Ca++ . Over several days, induced by Ca++ , the cells form pseudostratified shee
Autor:
Bhairavi Tolani, Anna Celli, Yanmin Yao, Yong Zi Tan, Richard Fetter, Christina R. Liem, Adam J. de Smith, Thamiya Vasanthakumar, Paola Bisignano, Adam D. Cotton, Ian B. Seiple, John L. Rubinstein, Marco Jost, Jonathan S. Weissman
Publikováno v:
Nature biotechnology, vol 40, iss 12
Mutations in Ras family proteins are implicated in 33% of human cancers, but direct pharmacological inhibition of Ras mutants remains challenging. As an alternative to direct inhibition, we screened for sensitivities in Ras-mutant cells and discovere
Autor:
Choe Joseph H, Anna Celli, Juhyun Cho, Kira Downey, Wei Yu, Olga G. Troyanskaya, Aileen W. Li, Diego Carrera, Ruth Dannenfelser, Yitzhar E. Goretsky, Kole T. Roybal, Jessica D. Briones, Sachdev S. Sidhu, Wendell A. Lim, Ryan Gilbert, Lia Cardarelli, Nira A. Krasnow, Milos S. Simic, Hideho Okada, Jason M. Duecker, Payal Watchmaker
Publikováno v:
Science translational medicine, vol 13, iss 591
Sci Transl Med
Sci Transl Med
Treatment of solid cancers with chimeric antigen receptor (CAR) T cells is plagued by the lack of ideal target antigens that are both absolutely tumor specific and homogeneously expressed. We show that multi-antigen prime-and-kill recognition circuit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b526cc204fad3a7a0516aa6cc3ee6df1
https://escholarship.org/uc/item/64p7w6f3
https://escholarship.org/uc/item/64p7w6f3
Publikováno v:
Journal of Investigative Dermatology. 139:919-929
Extracellular Ca2+ (Ca2+o) is a crucial regulator of epidermal homeostasis and its receptor, the Ca2+-sensing receptor (CaSR), conveys the Ca2+o signals to promote keratinocyte adhesion, differentiation, and survival via activation of intracellular C