Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Anna Caruso"'
Publikováno v:
Applied Sciences, Vol 14, Iss 18, p 8124 (2024)
Indole alkaloids, a class of plant-derived nitrogen-containing compounds, have emerged as promising candidates for osteoporosis treatment. Their favorable biocompatibility profile demonstrated efficacy in preclinical models, and low reported toxicity
Externí odkaz:
https://doaj.org/article/f9881cc0edc549edbf2ba1d8d1ce9548
TMBcalc: a computational pipeline for identifying pan-cancer Tumor Mutational Burden gene signatures
Autor:
Grete Francesca Privitera, Salvatore Alaimo, Anna Caruso, Alfredo Ferro, Stefano Forte, Alfredo Pulvirenti
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background:In the precision medicine era, identifying predictive factors to select patients most likely to benefit from treatment with immunological agents is a crucial and open challenge in oncology.Methods:This paper presents a pan-cancer analysis
Externí odkaz:
https://doaj.org/article/6c66c76d46664a4a9817ec92c3d87ff3
Autor:
Simona Todisco, Vittoria Infantino, Anna Caruso, Anna Santarsiero, Paolo Convertini, Hussein El-Kashef, Federica Giuzio, Maria Stefania Sinicropi, Carmela Saturnino
Publikováno v:
Applied Sciences, Vol 14, Iss 15, p 6747 (2024)
Cyclic-nucleotide phosphodiesterases (PDEs) represent a superfamily of enzymes playing a pivotal role in cell signaling by controlling cAMP and cGMP levels in response to receptor activation. PDE activity and expression are linked to many diseases in
Externí odkaz:
https://doaj.org/article/c0338026d75d49c9b77ff654eb7209b8
Autor:
Anna Caruso
Publikováno v:
Applied Sciences, Vol 13, Iss 7, p 4263 (2023)
The academic community has extensively explored, over the years, heterocyclic compounds of the carbazolic motif [...]
Externí odkaz:
https://doaj.org/article/37b6545a42e8480cad73ce5e873743b0
Autor:
Jessica Ceramella, Domenico Iacopetta, Anna Caruso, Annaluisa Mariconda, Anthi Petrou, Athina Geronikaki, Camillo Rosano, Carmela Saturnino, Alessia Catalano, Pasquale Longo, Maria Stefania Sinicropi
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 353 (2023)
Over the years, carbazoles have been largely studied for their numerous biological properties, including antibacterial, antimalarial, antioxidant, antidiabetic, neuroprotective, anticancer, and many more. Some of them have gained great interest for t
Externí odkaz:
https://doaj.org/article/c24a33626c15425fb9b05f91fee36452
Autor:
Maria Grazia Bonomo, Anna Caruso, Hussein El-Kashef, Giovanni Salzano, Maria Stefania Sinicropi, Carmela Saturnino
Publikováno v:
Applied Sciences, Vol 13, Iss 3, p 1522 (2023)
The Coronavirus disease 2019 (COVID-19) outbreak was declared by the World Health Organization (WHO) in March 2020 to be a pandemic and many drugs used at the beginning proved useless in fighting the infection. Lately, there has been approval of some
Externí odkaz:
https://doaj.org/article/6832b99dc0b748d793385465a6748e62
Autor:
Fedora Grande, Giuseppina Ioele, Anna Caruso, Maria Antonietta Occhiuzzi, Hussein El-Kashef, Carmela Saturnino, Maria Stefania Sinicropi
Publikováno v:
Applied Sciences, Vol 13, Iss 1, p 349 (2022)
Carbazole derivatives have gained a lot of attention in medicinal chemistry over the last few decades due to their wide range of biological and pharmacological properties, including antibacterial, antitumor, antioxidant, and anti-inflammatory activit
Externí odkaz:
https://doaj.org/article/589f222d6ce3425f8ba96066c4cfe747
Autor:
Maria Stefania Sinicropi, Domenico Iacopetta, Camillo Rosano, Rosario Randino, Anna Caruso, Carmela Saturnino, Noemi Muià, Jessica Ceramella, Francesco Puoci, Manuela Rodriquez, Pasquale Longo, Maria Rosaria Plutino
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 434-444 (2018)
Synthetic or natural carbazole derivatives constitute an interesting class of heterocycles, which showed several pharmaceutical properties and occupied a promising place as antitumour tools in preclinical studies. They target several cellular key-poi
Externí odkaz:
https://doaj.org/article/64117c54f1d04ccab71769181760a876
Autor:
Anna Caruso, Alexia Barbarossa, Alessia Carocci, Giovanni Salzano, Maria Stefania Sinicropi, Carmela Saturnino
Publikováno v:
Applied Sciences, Vol 11, Iss 13, p 6192 (2021)
The carbazole class is made up of heterocyclically structured compounds first isolated from coal tar. Their structural motif is preponderant in different synthetic materials and naturally occurring alkaloids extracted from the taxonomically related h
Externí odkaz:
https://doaj.org/article/08cf665545e044b1b77ebad986489fb6
Autor:
Fedora Grande, Anna De Bartolo, Maria Antonietta Occhiuzzi, Anna Caruso, Carmine Rocca, Teresa Pasqua, Alessia Carocci, Vittoria Rago, Tommaso Angelone, Maria Stefania Sinicropi
Publikováno v:
Applied Sciences, Vol 11, Iss 12, p 5486 (2021)
β-Adrenergic receptors (β-ARs) are G protein-coupled receptors involved in important physiological and pathological processes related to blood pressure and cardiac activity. The inhibition of cardiac β1-ARs could be beneficial in myocardial hypert
Externí odkaz:
https://doaj.org/article/4c0d4d49eab241aa9cd7d470b77dc375