Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Anna Caretti"'
Autor:
Michele Dei Cas, Linda Montavoci, Claudia Pasini, Anna Caretti, Sara Penati, Carla Martinelli, Umberto Gianelli, Sara Casati, Francesca Nardecchia, Annalaura Torella, Nicola Brunetti-Pierri, Marco Trinchera
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 3, Pp 100517- (2024)
The last step of ex novo ceramide biosynthesis consists of the conversion of dihydroceramide into ceramide catalyzed by sphingolipid Δ4-desaturase DEGS1. DEGS1 variants were found to be responsible for heterogeneous clinical pictures belonging to th
Externí odkaz:
https://doaj.org/article/c066db706c1b439f81926ed07b97410d
Autor:
Barbara Oliviero, Michele Dei Cas, Aida Zulueta, Roberta Maiello, Alessandro Villa, Carla Martinelli, Elena Del Favero, Monica Falleni, Linda Montavoci, Stefania Varchetta, Dalila Mele, Matteo Donadon, Cristiana Soldani, Barbara Franceschini, Marcello Maestri, Gaetano Piccolo, Matteo Barabino, Paolo Pietro Bianchi, Jesus M. Banales, Stefania Mantovani, Mario U. Mondelli, Anna Caretti
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Cholangiocarcinoma (CCA) is a rare cancer characterized by a global increasing incidence. Extracellular vesicles (EV) contribute to many of the hallmarks of cancer through transfer of their cargo molecules. The sphingolipid (SPL) profile of
Externí odkaz:
https://doaj.org/article/bb75d917f167424e9b8d30fa461784d6
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
A chronic inflammatory condition characterizes various lung diseases. Interestingly, a great contribution to inflammation is made by altered lipids metabolism, that can be caused by the deregulation of the mammalian target of rapamycin complex-1 (mTO
Externí odkaz:
https://doaj.org/article/5390e0b53bd94163a937cef54a30a85a
Autor:
Alessandra Mingione, Michele Dei Cas, Fabiola Bonezzi, Anna Caretti, Marco Piccoli, Luigi Anastasia, Riccardo Ghidoni, Rita Paroni, Paola Signorelli
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 1, Pp 110-125 (2020)
Externí odkaz:
https://doaj.org/article/8228dc3b013a47f88a02441d59fb84dd
Publikováno v:
Metabolites, Vol 12, Iss 5, p 450 (2022)
The main concerns in targeted “sphingolipidomics” are the extraction and proper handling of biological samples to avoid interferences and achieve a quantitative yield well representing all the sphingolipids in the matrix. Our work aimed to compar
Externí odkaz:
https://doaj.org/article/3ba6779863e349409ce1ef503896f587
Autor:
Aida Zulueta, Michele Dei Cas, Francesco Luciano, Alessandra Mingione, Francesca Pivari, Ilaria Righi, Letizia Morlacchi, Lorenzo Rosso, Paola Signorelli, Riccardo Ghidoni, Rita Paroni, Anna Caretti
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1121 (2021)
The role of S1P in Cystic Fibrosis (CF) has been investigated since 2001, when it was first described that the CFTR channel regulates the inward transport of S1P. From then on, various studies have associated F508del CFTR, the most frequent mutation
Externí odkaz:
https://doaj.org/article/b1bef89aafea47b38a89236a50173078
Autor:
Alessandra Mingione, Francesca Pivari, Nicoletta Plotegher, Michele Dei Cas, Aida Zulueta, Tommaso Bocci, Marco Trinchera, Elisabetta Albi, Vittorio Maglione, Anna Caretti, Luigi Bubacco, Rita Paroni, Daniele Bottai, Riccardo Ghidoni, Paola Signorelli
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6469 (2021)
Parkinson’s disease (PD) is a proteinopathy associated with the aggregation of α-synuclein and the formation of lipid–protein cellular inclusions, named Lewy bodies (LBs). LB formation results in impaired neurotransmitter release and uptake, whi
Externí odkaz:
https://doaj.org/article/1c3a7d8ac9114d9f9af011b484954eba
Autor:
Fabiola Bonezzi, Marco Piccoli, Michele Dei Cas, Rita Paroni, Alessandra Mingione, Michelle M. Monasky, Anna Caretti, Chiara Riganti, Riccardo Ghidoni, Carlo Pappone, Luigi Anastasia, Paola Signorelli
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Myocardial infarct requires prompt thrombolytic therapy or primary percutaneous coronary intervention to limit the extent of necrosis, but reperfusion creates additional damage. Along with reperfusion, a maladaptive remodeling phase might occur and i
Externí odkaz:
https://doaj.org/article/0ff7f95fe7bf4dafb966802efa48c519
Publikováno v:
Cancers, Vol 12, Iss 6, p 1509 (2020)
Carbohydrate antigen 19.9 (CA19.9) is used as a tumor marker for clinical and research purposes assuming that it is abundantly produced by gastrointestinal cancer cells due to a cancer-associated aberrant glycosylation favoring its synthesis. Recent
Externí odkaz:
https://doaj.org/article/50799848772840a7bb4e44e3e9084431
Autor:
Michele Dei Cas, Aida Zulueta, Alessandra Mingione, Anna Caretti, Riccardo Ghidoni, Paola Signorelli, Rita Paroni
Publikováno v:
Cells, Vol 9, Iss 5, p 1197 (2020)
Altered lipid metabolism has been associated to cystic fibrosis disease, which is characterized by chronic lung inflammation and various organs dysfunction. Here, we present the validation of an untargeted lipidomics approach based on high-resolution
Externí odkaz:
https://doaj.org/article/9d187b9ccbfb4a2bb761ed57dfe47020