Zobrazeno 1 - 10
of 411
pro vyhledávání: '"Anna Capasso"'
Autor:
Nisha Holay, Alexander Somma, Mark Duchow, Milad Soleimani, Anna Capasso, Srividya Kottapalli, Joshua Rios, Uma Giri, Jennifer Diamond, Anna Schreiber, Anthony D. Piscopio, Carla Van Den Berg, S. Gail Eckhardt, Todd A. Triplett
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Histone deacetylase inhibitors (HDACi) are currently being explored for the treatment of both solid and hematological malignancies. Although originally thought to exert cytotoxic responses through tumor-intrinsic mechanisms by increasing expression o
Externí odkaz:
https://doaj.org/article/fb11b1e8367b473a9f32db554b699b48
Autor:
Marika Pane, Beatrice Berti, Anna Capasso, Giorgia Coratti, Antonio Varone, Adele D’Amico, Sonia Messina, Riccardo Masson, Valeria Ada Sansone, Maria Alice Donati, Caterina Agosto, Claudio Bruno, Federica Ricci, Antonella Pini, Delio Gagliardi, Massimiliano Filosto, Stefania Corti, Daniela Leone, Concetta Palermo, Roberta Onesimo, Roberto De Sanctis, Martina Ricci, Ilaria Bitetti, Maria Sframeli, Claudia Dosi, Emilio Albamonte, Chiara Ticci, Noemi Brolatti, Enrico Bertini, Richard Finkel, Eugenio Mercuri, Maria Carmela Pera, Chiara Bravetti, Marco Piastra, Orazio Genovese, Gianpaolo Cicala, Nicola Forcina, Sara Carnicella, Giulia Stanca, Michele Sacchini, Michela Catteruccia, Michele Tosi, Renato Cutrera, Claudio Chierchi, Maria Beatrice Chiarini, Francesca Salmin, Marina Pedemonte, Alessandra Govoni, Irene Mizzoni, Simone Morando, Riccardo Zanin, Enrica Rolle, Eleonora Salomon, Melania Giannotta, Gaia Scarpini, Antonio Toscano, Eloisa Gitto, Roberto Materia, Rossella D’Alessandro
Publikováno v:
EClinicalMedicine, Vol 59, Iss , Pp 101997- (2023)
Summary: Background: Efficacy and safety of onasemnogene abeparvovec (OA) for Spinal Muscular Atrophy infants under 7 months and
Externí odkaz:
https://doaj.org/article/40165d9821824625a9a6285a88f2fdbc
Autor:
Marika Pane, Giorgia Coratti, Maria Carmela Pera, Valeria A. Sansone, Sonia Messina, Adele d'Amico, Claudio Bruno, Francesca Salmin, Emilio Albamonte, Roberto De Sanctis, Maria Sframeli, Vincenzo Di Bella, Simone Morando, Concetta Palermo, Anna Lia Frongia, Laura Antonaci, Anna Capasso, Michela Catteruccia, Antonella Longo, Martina Ricci, Costanza Cutrona, Alice Pirola, Chiara Bravetti, Marina Pedemonte, Noemi Brolatti, Enrico Bertini, Eugenio Mercuri, Italian ISMAC group
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 3, Pp 404-409 (2022)
Abstract The study reports real world data in type 2 and 3 SMA patients treated for at least 2 years with nusinersen. Increase in motor function was observed after 12 months and during the second year. The magnitude of change was variable across age
Externí odkaz:
https://doaj.org/article/ca19ba70fc7d4dc28c30c6fa96bec970
Autor:
Rossella Di Paola, Ananya De, Raafiah Izhar, Marianna Abate, Silvia Zappavigna, Anna Capasso, Alessandra F. Perna, Antonella La Russa, Giovambattista Capasso, Michele Caraglia, Mariadelina Simeoni
Publikováno v:
Genes, Vol 14, Iss 6, p 1257 (2023)
Chronic kidney disease (CKD) induces several systemic effects, including the accumulation and production of uremic toxins responsible for the activation of various harmful processes. Gut dysbiosis has been widely described in CKD patients, even in th
Externí odkaz:
https://doaj.org/article/2a55c4171216410badba91e1c64e0fd6
Autor:
Julie Lang, Alexis D. Leal, Juan A. Marín-Jiménez, Sarah J. Hartman, Jeremy Shulman, Natalie M. Navarro, Matthew S. Lewis, Anna Capasso, Stacey M. Bagby, Bethlehem W. Yacob, Morgan MacBeth, Brian M. Freed, S. Gail Eckhardt, Kimberly Jordan, Patrick J. Blatchford, Roberta Pelanda, Christopher H. Lieu, Wells A. Messersmith, Todd M. Pitts
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Immune checkpoint inhibitors have been found to be effective in metastatic MSI-high colorectal cancers (CRC), however, have no efficacy in microsatellite stable (MSS) cancers, which comprise the majority of mCRC cases. Cabozantinib is a small molecul
Externí odkaz:
https://doaj.org/article/4e169c4be6074370bda2cb5901dfda6f
Autor:
Preeti Kanikarla Marie, Alexey V. Sorokin, Lea A. Bitner, Rebecca Aden, Michael Lam, Ganiraju Manyam, Melanie N. Woods, Amanda Anderson, Anna Capasso, Natalie Fowlkes, Michael J. Overman, David G. Menter, Scott Kopetz
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Designing studies of immunotherapy is limited due to a lack of pre-clinical models that reliably predict effective immunotherapy responses. To address this gap, we developed humanized mouse models of colorectal cancer (CRC) incorporating patient-deri
Externí odkaz:
https://doaj.org/article/ec06ee797f544d198959a8dcc024cd38
Autor:
Rossella Di Paola, Ananya De, Anna Capasso, Sofia Giuliana, Roberta Ranieri, Carolina Ruosi, Antonella Sciarra, Caterina Vitagliano, Alessandra F. Perna, Giovambattista Capasso, Mariadelina Simeoni
Publikováno v:
Journal of Personalized Medicine, Vol 13, Iss 5, p 813 (2023)
Thyroid cancers require complex and heterogeneous therapies with different impacts on renal function. In our systematic literature review, we analyzed several aspects: renal function assessment, the impact of radiotherapy and thyroid surgery on kidne
Externí odkaz:
https://doaj.org/article/4a4a2c56fe954ecc9f2a38b18811e015
Autor:
Daniela P. R. Chieffo, Federica Moriconi, Marika Pane, Simona Lucibello, Elisabetta Ferraroli, Giulia Norcia, Martina Ricci, Anna Capasso, Gianpaolo Cicala, Bianca Buchignani, Giorgia Coratti, Costanza Cutrona, Monia Pelizzari, Claudia Brogna, Jos G. M. Hendriksen, Francesco Muntoni, Eugenio Mercuri
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 2, p 403 (2023)
The aim of the study was to retrospectively evaluate the consistency of longitudinal findings on intellectual functioning in DMD boys and their relationship to behavioral and neuropsychiatric difficulties. The cohort included 70 patients of age 3 to
Externí odkaz:
https://doaj.org/article/27f53a243d424604bb8748ba268aa041
Autor:
Walter Milano, Francesca Carizzone, Mariagabriella Foia, Magda Marchese, Mariafrancesca Milano, Biancamaria Saetta, Anna Capasso
Publikováno v:
Diseases, Vol 11, Iss 1, p 7 (2022)
Obesity is a chronic multifactorial disease that has become a serious health problem and is currently widespread over the world. It is, in fact, strongly associated with many other conditions, including insulin resistance, type 2 diabetes, cardiovasc
Externí odkaz:
https://doaj.org/article/28d3e1a608224358bb546d6024dc4a7b
Autor:
John J. Tentler, Julie Lang, Anna Capasso, Deog Joong Kim, Ely Benaim, Young B. Lee, Andrew Eisen, Stacey M. Bagby, Sarah J. Hartman, Betelehem W. Yacob, Brian Gittleman, Todd M. Pitts, Roberta Pelanda, S. Gail Eckhardt, Jennifer R. Diamond
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with limited systemic treatment options. RX-5902 is a novel anti-cancer agent that inhibits phosphorylated-p68 and thus attenuates nuclear β-catenin sign
Externí odkaz:
https://doaj.org/article/1dcda43bbcb945d6ae883320daa5d648