Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Anna Campalans"'
Autor:
Xhaferr Tanushi, Guillaume Pinna, Marie Vandamme, Capucine Siberchicot, Ostiane D’Augustin, Anne-Marie Di Guilmi, J. Pablo Radicella, Bertrand Castaing, Rebecca Smith, Sebastien Huet, François Leteurtre, Anna Campalans
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
One of the most abundant DNA lesions induced by Reactive oxygen species (ROS) is 8-oxoG, a highly mutagenic lesion that compromises genetic instability when not efficiently repaired. 8-oxoG is specifically recognized by the DNA-glycosylase OGG1 that
Externí odkaz:
https://doaj.org/article/fb33b2e5d9f54efa87ae4201e6d9c02a
Autor:
Natalia Rubanova, Guillaume Pinna, Jeremie Kropp, Anna Campalans, Juan Pablo Radicella, Anna Polesskaya, Annick Harel-Bellan, Nadya Morozova
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Functional genomics employs several experimental approaches to investigate gene functions. High-throughput techniques, such as loss-of-function screening and transcriptome profiling, allow to identify lists of genes potentially in
Externí odkaz:
https://doaj.org/article/c3ae9039774941eaa603e959c7d5317a
Autor:
Elia Henry, Inès Souissi-Sahraoui, Margaux Deynoux, Andréas Lefèvre, Vilma Barroca, Anna Campalans, Véronique Ménard, Julien Calvo, Françoise Pflumio, Marie-Laure Arcangeli
Publikováno v:
Haematologica, Vol 105, Iss 8 (2020)
Hematopoietic stem cells are responsible for life-long blood cell production and are highly sensitive to exogenous stresses. The effects of low doses of ionizing radiations on radiosensitive tissues such as the hematopoietic tissue are still unknown
Externí odkaz:
https://doaj.org/article/35cf9d4d045f40cfac3c1270d86d124c
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8360 (2020)
The most frequent DNA lesion resulting from an oxidative stress is 7,8-dihydro-8-oxoguanine (8-oxoG). 8-oxoG is a premutagenic base modification due to its capacity to pair with adenine. Thus, the repair of 8-oxoG is critical for the preservation of
Externí odkaz:
https://doaj.org/article/cfda7d4ece22429fad921d31fb755148
Autor:
Anna Campalans, J. Radicella
Publikováno v:
Bio-Protocol, Vol 6, Iss 5 (2016)
The DNA molecule is exposed to a multitude of damaging agents that can compromise its integrity: single (SSB) and double strand breaks (DSB), intra- or inter-strand crosslinks, base loss or modification, etc. Many different DNA repair pathways coexis
Externí odkaz:
https://doaj.org/article/0c949de7402f437aa829cc3828989818
Autor:
Leen Sarmini, Mohammed Meabed, Eirini Emmanouil, George Atsaves, Elena Robeska, Bolesław T Karwowski, Anna Campalans, Thanasis Gimisis, Andriy Khobta
Publikováno v:
Nucleic Acids Research.
Accumulation of DNA damage resulting from reactive oxygen species was proposed to cause neurological and degenerative disease in patients, deficient in nucleotide excision repair (NER) or its transcription-coupled subpathway (TC-NER). Here, we assess
Autor:
Ostiane D’Augustin, Virginie Gaudon, Capucine Siberchicot, Rebecca Smith, Catherine Chapuis, Jordane Depagne, Xavier Veaute, Didier Busso, Anne-Marie Di Guilmi, Bertrand Castaing, J Pablo Radicella, Anna Campalans, Sébastien Huet
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2023, pp.gkad243. ⟨10.1093/nar/gkad243⟩
Nucleic Acids Research, 2023, pp.gkad243. ⟨10.1093/nar/gkad243⟩
The DNA-glycosylase OGG1 oversees the detection and clearance of the 7,8-dihydro-8-oxoguanine (8-oxoG), which is the most frequent form of oxidized base in the genome. This lesion is deeply buried within the double-helix and its detection requires ca
Publikováno v:
Handbook of Chemical Biology of Nucleic Acids ISBN: 9789811613135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d22eda26d9d231d3a2055b674ac9c293
https://doi.org/10.1007/978-981-16-1313-5_50-1
https://doi.org/10.1007/978-981-16-1313-5_50-1
Autor:
Ostiane D’Augustin, Virginie Gaudon, Capucine Siberchicot, Rebecca Smith, Catherine Chapuis, Jordane Depagne, Xavier Veaute, Didier Busso, Anne-Marie Di Guilmi, Bertrand Castaing, J. Pablo Radicella, Anna Campalans, Sébastien Huet
The DNA-glycosylase OGG1 oversees the detection and clearance of the 7,8-dihydro-8-oxoguanine (8-oxoG), which is the most frequent form of oxidized base in the genome. This lesion is deeply buried within the double-helix and its detection requires ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9efbb6fc97e987449a02fd7dedf88378
https://doi.org/10.1101/2022.11.04.515179
https://doi.org/10.1101/2022.11.04.515179
Autor:
Isaline Bontemps, Celine Lallemand, Denis Biard, Nathalie Dechamps, Thierry Kortulewski, Emmanuelle Bourneuf, Capucine Siberchicot, François Boussin, Sylvie Chevillard, Anna Campalans, Jerome Lebeau
Publikováno v:
Oncology reports. 49(1)
SUMMARYThere is compelling evidence that cancer stem cells (CSCs) play an essential role in failure of conventional antitumor therapy. In breast cancer, CD24-/low/CD44+ phenotype as well as a high aldehyde dehydrogenase activity (ALDH+) are widely as