Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Anna C. Obenauf"'
Autor:
Lisa Haas, Anna C. Obenauf
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
For decades, cancer was considered a disease driven by genetic mutations in tumor cells, therefore afflicting a single cell type. This simplified view was slowly replaced by the understanding that interactions between malignant cells and neighboring
Externí odkaz:
https://doaj.org/article/9eaed869815a4f15b8a9095dafb8fead
Autor:
Katharina Schallmoser, Christina Bartmann, Eva Rohde, Simone Bork, Christian Guelly, Anna C. Obenauf, Andreas Reinisch, Patrick Horn, Anthony D. Ho, Dirk Strunk, Wolfgang Wagner
Publikováno v:
Haematologica, Vol 95, Iss 6 (2010)
Background Research on mesenchymal stromal cells has created high expectations for a variety of therapeutic applications. Extensive propagation to yield enough mesenchymal stromal cells for therapy may result in replicative senescence and thus hamper
Externí odkaz:
https://doaj.org/article/e2bfca2f2a674a7088eb1c661d6d1f67
Autor:
Lukas Leiendecker, Pauline S Jung, Izabela Krecioch, Tobias Neumann, Alexander Schleiffer, Karl Mechtler, Thomas Wiesner, Anna C Obenauf
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
Abstract Merkel cell carcinoma (MCC) is a highly aggressive, neuroendocrine skin cancer that lacks actionable mutations, which could be utilized for targeted therapies. Epigenetic regulators governing cell identity may represent unexplored therapeuti
Externí odkaz:
https://doaj.org/article/3e160d333a2f40228b3fd40c2109df55
Autor:
Anna C. Obenauf, Thomas Wiesner, Klaus G. Griewank, Frank Stubenrauch, Arno Rütten, Eduardo Calonje, Lorenzo Cerroni, Reinhard Kirnbauer, Babak Itzinger-Monshi, Klaus J. Busam, Rajmohan Murali, Etienne Coyaud, Kamel Bachiri, Estelle Laurent, Thibault Kervarrec, Karl Mechtler, Michael Schutzbier, Alexander Schleiffer, Thomas L. Steinacker, Shona M. Cronin, Pauline S. Jung, Tobias Neumann, Lukas Leiendecker
HPV42 consensus genomes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044218582a25b164784abcb6554da814
https://doi.org/10.1158/2159-8290.22541929
https://doi.org/10.1158/2159-8290.22541929
Autor:
Anna C. Obenauf, Thomas Wiesner, Klaus G. Griewank, Frank Stubenrauch, Arno Rütten, Eduardo Calonje, Lorenzo Cerroni, Reinhard Kirnbauer, Babak Itzinger-Monshi, Klaus J. Busam, Rajmohan Murali, Etienne Coyaud, Kamel Bachiri, Estelle Laurent, Thibault Kervarrec, Karl Mechtler, Michael Schutzbier, Alexander Schleiffer, Thomas L. Steinacker, Shona M. Cronin, Pauline S. Jung, Tobias Neumann, Lukas Leiendecker
The skin is exposed to viral pathogens, but whether they contribute to the oncogenesis of skin cancers has not been systematically explored. Here we investigated 19 skin tumor types by analyzing off-target reads from commonly available next-generatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abd88071e534661631075b72f22a14d
https://doi.org/10.1158/2159-8290.c.6549766.v1
https://doi.org/10.1158/2159-8290.c.6549766.v1
Autor:
Joan Massagué, Nicholas D. Socci, Agnes Viale, Mono Pirun, Anna C. Obenauf, Sakari Vanharanta, Leni S. Jacob
Supplementary Figure S5. Reintroduction of WT BRAF in metastatic cell populations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec3564696f65ed8fd148a0c15a38733
https://doi.org/10.1158/0008-5472.22404902
https://doi.org/10.1158/0008-5472.22404902
Autor:
Joan Massagué, Nicholas D. Socci, Agnes Viale, Mono Pirun, Anna C. Obenauf, Sakari Vanharanta, Leni S. Jacob
Supplementary Table S6. Primers used in this study are listed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a8076b5fe27eb1e19b97e8f041a51e
https://doi.org/10.1158/0008-5472.22404881
https://doi.org/10.1158/0008-5472.22404881
Autor:
Joan Massagué, Nicholas D. Socci, Agnes Viale, Mono Pirun, Anna C. Obenauf, Sakari Vanharanta, Leni S. Jacob
Supplementary Materials and Methods. This file contains Supplementary Methods, References, and Figure Legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce8968f3c1e55634dfca2e2c1cfe33a
https://doi.org/10.1158/0008-5472.22404899
https://doi.org/10.1158/0008-5472.22404899
Autor:
James S. Wilmott, David Hoffmann, Richard A. Scolyer, Anais Elewaut, Kevin J. Harrington, Harriet Witthock, Johannes Zuber, Christian Umkehrer, Olivier Michielin, Maria Novatchkova, Tobias Neumann, Lukas Leiendecker, Sebastian Carotta, Thomas Wiesner, Sakari Vanharanta, Georgina V. Long, Anna C. Obenauf, Izabela Krecioch, Ines Pires da Silva, Camille L. Gerard, Lisa Haas, Michel A. Cuendet, Malin Pedersen, Mario Kuttke
Publikováno v:
Nature Cancer. 2:693-708
How targeted therapies and immunotherapies shape tumors, and thereby influence subsequent therapeutic responses, is poorly understood. In the present study, we show, in melanoma patients and mouse models, that when tumors relapse after targeted thera
Autor:
Alexander Stiglbauer-Tscholakoff, Jelena Zinnanti, Anna C. Obenauf, Anoop Kavirayani, Katja Bühler, Paul Slezak, Lukas Nics, Patrick Heimel, Wolfgang Drexler, Lydia M. Zopf, Zhe Chen, Vanessa Fröhlich, Wolfgang Weninger, Andreas Walter, Stefan H. Geyer, Markus Mitterhauser, Susanne Reier, Thomas H. Helbich
Publikováno v:
Molecular Imaging and Biology
Tumor vasculature and angiogenesis play a crucial role in tumor progression. Their visualization is therefore of utmost importance to the community. In this proof-of-principle study, we have established a novel cross-modality imaging (CMI) pipeline t