Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Anna C Liang"'
Autor:
Takakuni Maki, Yoko Takahashi, Nobukazu Miyamoto, Anna C. Liang, Masafumi Ihara, Eng H. Lo, Ken Arai
Publikováno v:
Stem Cell Research, Vol 15, Iss 1, Pp 68-74 (2015)
Oligodendrocytes, which are the main cell type in cerebral white matter, are generated from their precursor cells (oligodendrocyte precursor cells: OPCs). However, the differentiation from OPCs to oligodendrocytes is disturbed under stressed conditio
Externí odkaz:
https://doaj.org/article/c21ef632d0664d4fb0d42d459e02a041
Autor:
Anna C. Liang, Emiri T. Mandeville, Takakuni Maki, Akihiro Shindo, Angel T. Som, Naohiro Egawa, Kanako Itoh, Tsu Tshen Chuang, John D. Mcneish, Julie C. Holder, Josephine Lok, Eng H. Lo, Ken Arai
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Aging and vascular comorbidities such as hypertension comprise critical cofactors that influence how the brain responds to stroke. Ischemic stress induces neurogenesis and oligodendrogenesis in younger brains. However, it remains unclear whether thes
Externí odkaz:
https://doaj.org/article/7f922247b54b4e03869f0a5b1867d9c6
Autor:
Seong-Ho Koh, Anna C Liang, Yoko Takahashi, Takakuni Maki, Akihiro Shindo, Noriko Osumi, Jing Zhao, Hong Lin, Julie C Holder, Tsu Tshen Chuang, John D McNeish, Ken Arai, Eng H Lo
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138724 (2015)
Adult mammalian brain can be plastic after injury and disease. Therefore, boosting endogenous repair mechanisms would be a useful therapeutic approach for neurological disorders. Isoxazole-9 (Isx-9) has been reported to enhance neurogenesis from neur
Externí odkaz:
https://doaj.org/article/b9dd175d20b44bf8ae6c1950c4205930
Autor:
Ji Hae Seo, Takakuni Maki, Mitsuyo Maeda, Nobukazu Miyamoto, Anna C Liang, Kazuhide Hayakawa, Loc-Duyen D Pham, Fumihiko Suwa, Akihiko Taguchi, Tomohiro Matsuyama, Masafumi Ihara, Kyu-Won Kim, Eng H Lo, Ken Arai
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103174 (2014)
Trophic coupling between cerebral endothelium and their neighboring cells is required for the development and maintenance of blood-brain barrier (BBB) function. Here we report that oligodendrocyte precursor cells (OPCs) secrete soluble factor TGF-β1
Externí odkaz:
https://doaj.org/article/59584deb9ae34d6998fd58c2ac00f6c6
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 7 (2013)
White matter dysfunction is an important part of many CNS disorders including multiple sclerosis and vascular dementia. Within injured areas, myelin loss and oligodendrocyte death may trigger endogenous attempts at regeneration. However, during disea
Externí odkaz:
https://doaj.org/article/b8724d0cb7f2441abf055c22946cbe52
Autor:
Elga Esposito, Su Jing Chan, Changhong Xing, Kyu-Won Kim, Kazuhide Hayakawa, Bum Ju Ahn, Eng H. Lo, Ken Arai, Anna C. Liang
Publikováno v:
Journal of Neurochemistry. 146:160-172
Ischemic postconditioning is increasingly being investigated as a therapeutic approach for cerebral ischemia. However, the majority of studies are focused on the acute protection of neurons per se. Whether and how postconditioning affects multiple ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be4992967530f69545797686eda8d1d
https://doi.org/10.1111/jnc.14337
https://doi.org/10.1111/jnc.14337
Autor:
Hajime Takase, Josephine Lok, Loc-Duyen D. Pham, Eng H. Lo, Gen Hamanaka, Ken Arai, Nobukazu Miyamoto, Ryo Ohtomo, Takakuni Maki, Anna C. Liang
Publikováno v:
Neuroscience Letters. 668:120-125
Oligodendrocyte precursor cells (OPCs) play critical roles in maintaining the number of oligodendrocytes in white matter. Previously, we have shown that oxidative stress dampens oligodendrocyte regeneration after white matter damage, while a clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411169b86ee9a856ab7e1ec2b6d6cab5
https://doi.org/10.1016/j.neulet.2018.01.018
https://doi.org/10.1016/j.neulet.2018.01.018
Autor:
Josephine Lok, Naoki Itoh, Takakuni Maki, Akihiro Shindo, Eng H. Lo, Anna C. Liang, Ken Arai, Kanako Itoh, Naohiro Egawa
Publikováno v:
Neuroscience Research. 106:66-69
Hypoxic-ischemic (HI) brain injury in newborns results in serious damage. Magnesium sulfate has been clinically used as a cyto-protective agent against HI brain injury in newborns in some countries, including Japan. However, it is not clear how magne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72bb345bd2e431bb9cec664ca8dc964
https://doi.org/10.1016/j.neures.2015.12.004
https://doi.org/10.1016/j.neures.2015.12.004
Autor:
Evan K. Lo, Nobukazu Miyamoto, Takakuni Maki, Naohiro Egawa, Kanako Itoh, Masafumi Ihara, Mitsuyo Maeda, Ken Arai, Anna C. Liang, Josephine Lok, Akihiro Shindo
Publikováno v:
The Journal of Neuroscience. 35:14002-14008
Oligodendrocyte precursor cells (OPCs) in the adult brain contribute to white matter homeostasis. After white matter damage, OPCs compensate for oligodendrocyte loss by differentiating into mature oligodendrocytes. However, the underlying mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c4403fb457208df85a6b9eb927c04c
https://doi.org/10.1523/jneurosci.1592-15.2015
https://doi.org/10.1523/jneurosci.1592-15.2015
Autor:
Eng H. Lo, Takakuni Maki, Anna C. Liang, Nobukazu Miyamoto, Akihiro Shindo, Ken Arai, Hidekazu Tomimoto
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 36:187-198
Oligodendrocytes are one of the major cell types in cerebral white matter. Under normal conditions, they form myelin sheaths that encircle axons to support fast nerve conduction. Under conditions of cerebral ischemia, oligodendrocytes tend to die, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13feaa8bd105aea0460f1f5c9a971d3a
https://doi.org/10.1038/jcbfm.2015.80
https://doi.org/10.1038/jcbfm.2015.80