Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anna Byczek"'
Publikováno v:
Molecules, Vol 29, Iss 21, p 5149 (2024)
3,4-Dichloro-5-hydroxy-2(5H)-furanone and its dibromo analog are highly reactive molecules. Both are members of the 2(5H)-furanone family, which are important as pharmacophores present in drugs and natural products. Compounds possessing the 2(5H)-fur
Externí odkaz:
https://doaj.org/article/1e59e1e2ea6d4f22aa3ce32b648f4438
Autor:
Agata Raczyńska, Patryk Kapica, Katarzyna Papaj, Agnieszka Stańczak, Divine Shyntum, Patrycja Spychalska, Anna Byczek-Wyrostek, Artur Góra
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0280776 (2023)
The haloalkane dehalogenase LinB is a well-known enzyme that contains buried active site and is used for many modelling studies. Using classical molecular dynamics simulations of enzymes and substrates, we searched for transient binding sites on the
Externí odkaz:
https://doaj.org/article/8d0b66bfe41d451d85873b96028d725e
Autor:
Katarzyna Żurawska, Daria Burdalska, Magdalena Skonieczna, Anna Byczek-Wyrostek, Anahit Dawicka, Anna Kasprzycka, Krzysztof Walczak
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 525 (2023)
The pharmacological effects of the presence of a sugar moiety, 1,2,3-triazole ring and silyl groups in the structure of biologically active compounds have been extensively studied in drug design and medicinal chemistry. These components can be useful
Externí odkaz:
https://doaj.org/article/8d39cac98a784d40b89bc5a13fc49634
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1079 (2021)
The pharmacological effects of carbon to silicon bioisosteric replacements have been widely explored in drug design and medicinal chemistry. Here, we present a systematic investigation of the impact of different silyl groups on the anticancer activit
Externí odkaz:
https://doaj.org/article/2e9510c367bf467eb0f61b2b60ff04f6
Autor:
Wieslaw Szeja, Grzegorz Grynkiewicz, Tadeusz Bieg, Piotr Swierk, Anna Byczek, Katarzyna Papaj, Radosław Kitel, Aleksandra Rusin
Publikováno v:
Molecules, Vol 19, Iss 6, Pp 7072-7093 (2014)
A series of glycoconjugates, derivatives of genistein containing a C-glycosylated carbohydrate moiety, were synthesized and their anticancer activity was tested in vitro in the human cell lines HCT 116 and DU 145. The target compounds 15–17 were sy
Externí odkaz:
https://doaj.org/article/73c89522c53a4f90a9b022dac9b5366f
Publikováno v:
Pharmaceuticals, Vol 14, Iss 1079, p 1079 (2021)
Pharmaceuticals
Volume 14
Issue 11
Pharmaceuticals
Volume 14
Issue 11
The pharmacological effects of carbon to silicon bioisosteric replacements have been widely explored in drug design and medicinal chemistry. Here, we present a systematic investigation of the impact of different silyl groups on the anticancer activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f680f3d743c2dadaa4be56b6a7a47586
https://ruj.uj.edu.pl/xmlui/handle/item/285055
https://ruj.uj.edu.pl/xmlui/handle/item/285055
Autor:
Andrzej Milewski, Agata Jakóbik-Kolon, Tomasz Krawczyk, Anna Kasprzycka, Anna Byczek-Wyrostek, Małgorzata Burek, Dymitr Czechowicz, Sylwia Waśkiewicz, Dorota Babilas, Piotr Dydo
Publikováno v:
ACS Sustainable Chemistry & Engineering. 6:13208-13216
An alternate method of synthesizing oligoglycerols from glycerol—epichlorohydrin—KOH mixtures at room temperature is proposed. This method involves using triethanolamine as a catalyst and produced ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65db574df6dc9a690c0052afa9d08b2c
https://doi.org/10.1021/acssuschemeng.8b02817
https://doi.org/10.1021/acssuschemeng.8b02817
Autor:
Anna Byczek-Wyrostek, Roman Komor, Karol Erfurt, Wiesław Szeja, Gabriela Pastuch-Gawołek, Mateusz Plesniak
Publikováno v:
Bioorganic Chemistry. 72:80-88
A series of UDP-sugar analogues was synthesized and their preliminary biological activity was evaluated. Glycoconjugates of uridine 1 and 2 were synthesized by condensation of uridine-5'-carboxylic acid and 1-amino sugars derivatives of d-glucose and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305644b407e0f0bf4832cabd0ed32883
https://doi.org/10.1016/j.bioorg.2017.03.015
https://doi.org/10.1016/j.bioorg.2017.03.015
Autor:
Klaudia Strama, Przemysław Kasprzycki, Anna Byczek-Wyrostek, Martyna Wawszków, Krzysztof Walczak, Mateusz D. Tomczyk
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 15(5)
Background: The substituted 1,8-Naphthalimides (1H-benzo[de]isoquinoline-1,3(2H)- diones) are known as DNA intercalators stabilizing DNA-Topoisomerase II complexes. This interaction disrupts the cleavage-relegation equilibrium of Topo II, resulting i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d769bffdb98e3c70a38738146ac92d43
https://pubmed.ncbi.nlm.nih.gov/30207241
https://pubmed.ncbi.nlm.nih.gov/30207241
Autor:
Anna Kasprzycka, Radoslaw Kitel, Klaudia Rumak, Magdalena Skonieczna, Krzysztof Walczak, Anna Byczek-Wyrostek
A series of 5-alkoxy derivatives of 3,4-dichloro-5-hydroxyfuran-2-(5H)-one (mucochloric acid, MCA) were obtained and subsequently subjected to modification in the C-4 position of 2(5H)-furanone ring. The cytotoxicity of newly synthesized compounds wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59594160c1b646544f1517c7abe689e0
https://ruj.uj.edu.pl/xmlui/handle/item/63439
https://ruj.uj.edu.pl/xmlui/handle/item/63439