Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anna Buda"'
Autor:
Piotr J. Wysocki, Mateusz Łobacz, Paweł Potocki, Łukasz Kwinta, Anna Michałowska-Kaczmarczyk, Agnieszka Słowik, Kamil Konopka, Anna Buda-Nowak
Publikováno v:
Cancers
Volume 15
Issue 4
Pages: 1067
Volume 15
Issue 4
Pages: 1067
Patients with advanced ovarian cancer (OC) have a detrimental prognosis. The options for systemic treatment of advanced OC in later lines of treatment are limited by the availability of active therapies and their applicability to often fragile, exhau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df114fa5afecd23dc3337f205728dc1
https://ruj.uj.edu.pl/xmlui/handle/item/309168
https://ruj.uj.edu.pl/xmlui/handle/item/309168
Publikováno v:
Cancer Research. 83:P3-01
Introduction: The development of resistance to endocrine treatment (HTH) can result from various biological mechanisms not only related to ER function but also to activation of multiple signaling pathways, which make HTH insufficient to control cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b2641641410542a7306205431ca581
https://doi.org/10.1158/1538-7445.sabcs22-p3-01-08
https://doi.org/10.1158/1538-7445.sabcs22-p3-01-08
Autor:
Anna Buda-Nowak, Łukasz Kwinta, Paweł Potocki, Anna Michałowska-Kaczmarczyk, Agnieszka Słowik, Kamil Konopka, Joanna Streb, Maciej Koniewski, Piotr J. Wysocki
Publikováno v:
Journal of Clinical Medicine
Volume 12
Issue 4
Pages: 1350
Volume 12
Issue 4
Pages: 1350
Background: Breast cancer, with 2.3 million new cases and 0.7 million deaths every year, represents a great medical challenge worldwide. These numbers confirm that approx. 30% of BC patients will develop an incurable disease requiring life-long, pall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48266d77b54ff36bef071035aecd7884
https://doi.org/10.3390/jcm12041350
https://doi.org/10.3390/jcm12041350
Autor:
Charles-Henry Fabritius, Paulina Węgrzyn, Agata Stasiowska, Marta Bugaj, Andrzej Mazan, Monika Dobrzańska, Karolina Gluza, Piotr Kowalczyk, Ewa Kolasińska, Adrian Zarebski, Przemyslaw Zawadzki, Karolina Krawczynska, Aneta Bobowska, Anna Cierpich, Małgorzata Żurawska, Nicolas Boutard, Mariusz Milik, Katarzyna Wiklik, Anna Buda, Małgorzata Jarosz, Krzysztof Brzózka, Aleksandra Sabiniarz, Mariusz Galek, Edyta Palacz, Klaudia Czerwińska, Claude Commandeur
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:607-613
Maternal embryonic leucine zipper kinase (MELK) is involved in several key cellular processes and displays increased levels of expression in numerous cancer classes (colon, breast, brain, ovary, prostate and lung). Although no selective MELK inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0811d2cb5e37f7797b44a0953a2ff63
https://doi.org/10.1016/j.bmcl.2018.12.051
https://doi.org/10.1016/j.bmcl.2018.12.051
Autor:
Nicolas Boutard, Arkadiusz Białas, Aleksandra Sabiniarz, Paweł Guzik, Katarzyna Banaszak, Artur Biela, Marcin Bień, Anna Buda, Barbara Bugaj, Ewelina Cieluch, Anna Cierpich, Łukasz Dudek, Hans-Michael Eggenweiler, Joanna Fogt, Monika Gaik, Andrzej Gondela, Krzysztof Jakubiec, Mirek Jurzak, Agata Kitlińska, Piotr Kowalczyk, Maciej Kujawa, Katarzyna Kwiecińska, Marcin Leś, Ralph Lindemann, Monika Maciuszek, Maciej Mikulski, Paulina Niedziejko, Alicja Obara, Henryk Pawlik, Tomasz Rzymski, Magdalena Sieprawska-Lupa, Marta Sowińska, Joanna Szeremeta-Spisak, Agata Stachowicz, Mateusz M. Tomczyk, Katarzyna Wiklik, Łukasz Włoszczak, Sylwia Ziemiańska, Adrian Zarębski, Krzysztof Brzózka, Mateusz Nowak, Charles-Henry Fabritius
In oncology, the "Warburg effect" describes the elevated production of energy by glycolysis in cancer cells. The ubiquitous and hypoxia-induced 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) plays a noteworthy role in the regulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef37f4c1c80edce81f72f55d3f7931e
https://ruj.uj.edu.pl/xmlui/handle/item/252764
https://ruj.uj.edu.pl/xmlui/handle/item/252764
Autor:
Marta Olszak-Płachta, Mateusz Nowak, Hugh Chapman, Magdalena Sieprawska-Lupa, Raymond Horvath, Klaudia Stefańska, Maciej Mikulski, Marcin Król, Katja Kuokkanen, Michal Galezowski, Mariusz Galek, Niina Jalava, Justyna Adamczyk, Joanna Szeremeta-Spisak, Ullamari Pesonen, Josef Messinger, Harri Salo, Radosław Obuchowicz, Charles-Henry Fabritius, Anna Buda, Peteris Prusis, Timo Korjamo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:2610-2615
A series of 1-Sulfonyl-6-Piperazinyl-7-Azaindoles, showing strong antagonistic activity to 5-HT6 receptor (5-HT6R) was synthesized and characterized. The series was optimized to reduce activity on D2 receptor. Based on the selectivity against this of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0e7ddf2aebc8b11e2dc823531d7081
https://doi.org/10.1016/j.bmcl.2016.04.024
https://doi.org/10.1016/j.bmcl.2016.04.024
Autor:
Zsófia Csizek, Eszter Mikó-Baráth, Anna Budai, Andrew B. Frigyik, Ágota Pusztai, Vanda A. Nemes, László Závori, Diána Fülöp, András Czigler, Kitti Szabó-Guth, Péter Buzás, David P. Piñero, Gábor Jandó
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionThe development of costs-effective and sensitive screening solutions to prevent amblyopia and identify its risk factors (strabismus, refractive problems or mixed) is a significant priority of pediatric ophthalmology. The main objective of
Externí odkaz:
https://doaj.org/article/6f03e8667c0d4bd2bc3f6275791ac6bc
Autor:
K. Banaszak, M. Gaik, M. Maciuszek, A. Gondela, A. Stachowicz, A. Bialas, A. Kitlinska, K. Kwiecinska, H.M. Eggenweiler, M. Bien, L. Wloszczak, Mateusz Michał Tomczyk, P. Guzik, Magdalena Sieprawska-Lupa, Piotr Kowalczyk, M. Jurzak, Marta Sowinska, M. Les, Mateusz Nowak, Aleksandra Sabiniarz, S. Ziemianska, B. Bugaj, Maciej Mikulski, Nicolas Boutard, L. Dudek, Anna Cierpich, A. Biela, R. Lindemann, Adrian Zarebski, H. Pawlik, J. Fogt, E. Cieluch, Joanna Szeremeta-Spisak, Krzysztof Brzózka, T. Rzymski, M. Kujawa, K. Jakubiec, C.H. Fabritius, Katarzyna Wiklik, A. Obara, Anna Buda, P. Niedziejko
Publikováno v:
ChemMedChem. 14(1)
Energy and biomass production in cancer cells are largely supported by aerobic glycolysis in what is called the Warburg effect. The process is regulated by key enzymes, among which phosphofructokinase PFK-2 plays a significant role by producing fruct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4e2e375f345b45513bf24c44f0ee4c
https://pubmed.ncbi.nlm.nih.gov/30378281
https://pubmed.ncbi.nlm.nih.gov/30378281
Autor:
Anna, Buda-Nowak, Małgorzata, Swiąder, Mirosława, Püsküllüoğlu, Grzegorz, Dyduch, Maciej, Krupiński, Krzysztof, Krzemieniecki
Publikováno v:
Przeglad lekarski. 72(7)
Adenoid cystic carcinoma (ACC) of the external auditory canal (EAC) is an exceedingly rare tumor. Despite the slow growth it is characterized by a high malignancy and infiltration of surrounding tissue. Differential diagnosis may be especially diffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4d334e6e892ecddaf20c2a0be79ddd9
https://pubmed.ncbi.nlm.nih.gov/26817353
https://pubmed.ncbi.nlm.nih.gov/26817353
Publikováno v:
ARPHA Proceedings, Vol 5, Iss , Pp 193-204 (2022)
The article represents the practices of an innovative teacher training management model implemented by the Institute of Education, the Immanuel Kant Baltic Federal University (Kaliningrad, Russia), within the framework of the pedagogical education de
Externí odkaz:
https://doaj.org/article/3a337e3a584e4090a7354c1122672a45