Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anna Bobyn"'
Autor:
Ana Nikolic, Francesca Maule, Anna Bobyn, Katrina Ellestad, Seungil Paik, Sajid A. Marhon, Parinaz Mehdipour, Xueqing Lun, Huey-Miin Chen, Claire Mallard, Alexander J. Hay, Michael J. Johnston, Christopher J. Gafuik, Franz J. Zemp, Yaoqing Shen, Nicoletta Ninkovic, Katalin Osz, Elodie Labit, N. Daniel Berger, Duncan K. Brownsey, John J. Kelly, Jeff Biernaskie, Peter B. Dirks, Darren J. Derksen, Steven J. M. Jones, Donna L. Senger, Jennifer A. Chan, Douglas J. Mahoney, Daniel D. De Carvalho, Marco Gallo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Self-renewal is a crucial property of glioblastoma cells that is enabled by the choreographed functions of chromatin regulators and transcription factors. Identifying targetable epigenetic mechanisms of self-renewal could therefore represent
Externí odkaz:
https://doaj.org/article/028fa80da48448499589471060a20e19
Autor:
Anna Bobyn, Mehdi Zarrei, Yuankun Zhu, Mary Hoffman, Darren Brenner, Adam C. Resnick, Stephen W. Scherer, Marco Gallo
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Pediatric high-grade gliomas (pHGGs) are incurable malignant brain cancers. Clear somatic genetic drivers are difficult to identify in the majority of cases. We hypothesized that this may be due to the existence of germline varian
Externí odkaz:
https://doaj.org/article/30749af6496a40a89a594ccaf2bc8ad5
Autor:
Stephen W. Scherer, Mehdi Zarrei, Anna Bobyn, Adam C. Resnick, Darren R. Brenner, Mary Hoffman, Marco Gallo, Yuankun Zhu
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Medical Genetics
BMC Medical Genetics
Background Pediatric high-grade gliomas (pHGGs) are incurable malignant brain cancers. Clear somatic genetic drivers are difficult to identify in the majority of cases. We hypothesized that this may be due to the existence of germline variants that i
Autor:
Gregory M.T. Guilcher, Jennifer A. Chan, Michael J. Johnston, Anna Bobyn, Bob Argiropoulos, Claire Mallard, Ana Nikolic, Marco Gallo
Publikováno v:
Cold Spring Harbor Molecular Case Studies
B-cell acute lymphoblastic leukemia (B-ALL) is often driven by chromosome translocations that result in recurrent and well-studied gene fusions. Currently, fluorescent in situ hybridization probes are used to detect candidate translocations in bone m
Autor:
Ana Nikolic, Anna Bobyn, Francesca Maule, Katrina Ellestad, Seungil Paik, Sajid Marhon, Parinaz Mehdipour, Xuequng Lun, Michael Johnston, Christopher Gafiuk, Franz Zemp, Yaoqing Shen, Nicoletta Ninkovic, Elodie Labit, N Daniel Berger, Duncan Brownsey, John Kelly, Jeff Biernaskie, Peter Dirks, Darren Derksen, Steven J M Jones, Donna L Senger, Jennifer Chan, Douglas J Mahoney, Daniel de Carvalho, Marco Gallo
Publikováno v:
Neuro-Oncology. 24:vii34-vii34
Glioblastoma is a highly malignant tumour driven by a subset of self-renewing cells termed glioblastoma stem cells. This self-renewal phenotype is largely epigenetically driven, however, the exact epigenetic mechanisms underpinning it are poorly unde
Autor:
Anna Bobyn, Michael J. Johnston, Gregory M.T. Guilcher, Ana Nikolic, Claire Mallard, Bob Argiropoulos, Marco Gallo, Jennifer A. Chan
B-cell acute lymphoblastic leukemia (B-ALL) is often driven by chromosome translocations that result in recurrent and well-studied gene fusions. Currently, fluorescent in-situ hybridization probes are employed to detect candidate translocations in bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7274a5496643af051a124de204ca5a6
https://doi.org/10.1101/2021.10.01.21264442
https://doi.org/10.1101/2021.10.01.21264442
Autor:
Michael J. Johnston, Parinaz Mehdipour, Douglas J. Mahoney, Katrina Ellestad, Christopher J Gafuik, Jennifer A. Chan, Ana Nikolic, Daniel D. De Carvalho, Nicoletta Ninkovic, Steven J.M. Jones, Xueqing Lun, Anna Bobyn, Peter B. Dirks, Francesca Maule, Yaoqing Shen, Darren J. Derksen, N. Daniel Berger, Donna L. Senger, Duncan K. Brownsey, Marco Gallo, Franz J. Zemp, Sajid A. Marhon
SUMMARYSelf-renewal is a crucial property of glioblastoma cells and is enabled by the choreographed function of chromatin regulators and transcription factors. Identifying targetable epigenetic mechanisms of self-renewal could represent an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe58287f85fb3fd3054c88f6e24aee0
https://doi.org/10.1101/2021.02.23.432465
https://doi.org/10.1101/2021.02.23.432465