Glycan Nanobiosensors

Autor: Filip Kveton, Anna Blsakova, Peter Kasak, Jan Tkac

Publikováno v: Nanomaterials, Vol 10, Iss 7, p 1406 (2020)

This review paper comprehensively summarizes advances made in the design of glycan nanobiosensors using diverse forms of nanomaterials. In particular, the paper covers the application of gold nanoparticles, quantum dots, magnetic nanoparticles, carbo

Externí odkaz: https://doaj.org/article/6b25e616b7e54eb0968f040a03d029ba

Glycan-modified interfaces in biosensing: an electrochemical approach

Autor: Jan Tkac, Filip Kveton, Anna Blsakova

Publikováno v: Current Opinion in Electrochemistry. 14:60-65

Glycans (complex carbohydrates) attached to various interfacial layers represent a simple but functional model of a cellular surface, which is covered densely by glycans. In this review, we discuss interactions of surface-confined glycans with variou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1e4262d3ecbb6ab3afc616691b74f93
https://doi.org/10.1016/j.coelec.2018.12.011

Optimization of the Small Glycan Presentation for Binding a Tumor-Associated Antibody: Application to the Construction of an Ultrasensitive Glycan Biosensor

Autor: Jan Tkac, Anna Blsakova, Ola Blixt, Pavel Damborsky, Andras Hushegyi, Bo Jansson, Filip Kveton

Publikováno v: Langmuir. 33:2709-2716

The main aim of the study was to optimize the interfacial presentation of a small antigen - a Tn antigen (N-acetylgalactosamine) - for binding to its analyte anti-Tn antibody. Three different methods for the interfacial display of a small glycan are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad9d605481cd4b7c136db0863f21527
https://doi.org/10.1021/acs.langmuir.6b04021

A graphene-based glycan biosensor for electrochemical label-free detection of a tumor-associated antibody

Autor: Anna Blsakova, Peter Kasak, Jan Tkac, Monika Jerigova, Dusan Velic, Ola Blixt, Filip Kveton, Bo Jansson, Lenka Lorencova

Publikováno v: Kveton, F, Blsakova, A, Lorencova, L, Jerigova, M, Velic, D, Blixt, O, Jansson, B, Kasak, P & Tkac, J 2019, ' A Graphene-Based Glycan Biosensor for Electrochemical Label-Free Detection of a Tumor-Associated Antibody ', Sensors, vol. 19, no. 24, 5409, pp. 1-13 . https://doi.org/10.3390/s19245409
Sensors
Volume 19
Issue 24
Sensors (Basel, Switzerland)

The study describes development of a glycan biosensor for detection of a tumor-associated antibody. The glycan biosensor is built on an electrochemically activated/oxidized graphene screen-printed electrode (GSPE). Oxygen functionalities were subsequ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4504f4deab761ef89feac13f1bf88cd
https://hdl.handle.net/10576/13580

Antibodies against aberrant glycans as cancer biomarkers.

Autor: Blsakova, Anna, Kveton, Filip, Kasak, Peter, Tkac, Jan

Publikováno v: Expert Review of Molecular Diagnostics; Dec2019, Vol. 19 Issue 12, p1057-1068, 12p