Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anna Besschetnova"'
Autor:
Wanting Han, Mingyu Liu, Dong Han, Muqing Li, Anthia A. Toure, Zifeng Wang, Anna Besschetnova, Susan Patalano, Jill A. Macoska, Shuai Gao, Housheng Hansen He, Changmeng Cai
Publikováno v:
Oncogene. 41:852-864
Genomic loss of RB1 is a common alteration in castration-resistant prostate cancer (CRPC) and is associated with poor patient outcomes. RB1 loss is also a critical event that promotes the neuroendocrine transdifferentiation of prostate cancer (PCa) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6359b932b0660e73ea37e465825b41
https://doi.org/10.1038/s41388-021-02135-3
https://doi.org/10.1038/s41388-021-02135-3
Autor:
Changmeng Cai, Susan Patalano, My Phu Luong, Yi Liang, Steven P. Balk, Muqing Li, Wanting Han, Anna Besschetnova, Housheng Hansen He, Jude Owiredu, Dong Han, Eva Corey, David Barrett, Zifeng Wang, Mingyu Liu, Jessica Petricca, Musaddeque Ahmed, Shuai Gao, Feng Zhou, Sen Chen, Jill A. Macoska, Sujun Chen
Publikováno v:
Nature genetics
FOXA1 functions as a pioneer transcription factor by facilitating the access to chromatin for steroid hormone receptors, such as androgen receptor and estrogen receptor1-4, but mechanisms regulating its binding to chromatin remain elusive. LSD1 (KDM1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31dffad0f00463df67b22a66a22017e
http://europepmc.org/articles/PMC7541538
http://europepmc.org/articles/PMC7541538
Autor:
Anna Besschetnova, Wanting Han, Mingyu Liu, Yanfei Gao, Muqing Li, Zifeng Wang, Maryam Labaf, Susan Patalano, Kavita Venkataramani, Rachel Muriph, Jill Macoska, Kellee Siegfried-Harris, Jason Evans, Steven Balk, Shuai Gao, Dong Han, Changmeng Cai
Publikováno v:
Cancer Research. 82:A021-A021
Background: Prostate Cancer (PCa) progresses to a metastatic form of cancer called Castration-Resistant Prostate Cancer (CRPC) after treatment with androgen deprivation therapies (ADTs). Epigenetic reprogramming through altered expression and activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07429b2c4ce7895109e9b5497844a1d9
https://doi.org/10.1158/1538-7445.cancepi22-a021
https://doi.org/10.1158/1538-7445.cancepi22-a021
Autor:
Wanting Han, Mingyu Liu, Dong Han, Anthia A. Toure, Muqing Li, Anna Besschetnova, Zifeng Wang, Susan Patalano, Jill A. Macoska, Hung-Ming Lam, Eva Corey, Housheng Hansen He, Shuai Gao, Steven P. Balk, Changmeng Cai
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 30(4)
The androgen receptor (AR) plays a pivotal role in driving prostate cancer (PCa) development. However, when stimulated by high levels of androgens, AR can also function as a tumor suppressor in PCa cells. While the high-dose testosterone (high-T) tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b202aafe5408d5a5cd1416c3bb5a1d
https://pubmed.ncbi.nlm.nih.gov/35121110
https://pubmed.ncbi.nlm.nih.gov/35121110
Publikováno v:
Cancer Research. 81:2152-2152
Background: Lysine methylation is an important post-translational regulation on histones, but its molecular functions on non-histone proteins remain largely unknown. In a pilot study, we identified novel lysine methylations at non-histone proteins in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96e9f301857a34cc885323a4d3b7172d
https://doi.org/10.1158/1538-7445.am2021-2152
https://doi.org/10.1158/1538-7445.am2021-2152