Effectiveness of an adaptive, multifaceted intervention to enhance care for patients with complex multimorbidity in general practice: protocol for a pragmatic cluster randomised controlled trial (the MM600 trial)

Autor: Per Kallestrup, Anne Frølich, Frans Boch Waldorff, Susanne Reventlow, Volkert Siersma, Anne Møller, Dagný Rós Nicolaisdóttir, Janus Laust Thomsen, Tora Grauers Willadsen, Jesper Bo Nielsen, Line Bjørnskov Pedersen, Henrik Larsen, Anne Holm, Anders Prior, Ann Dorrit Guassora, Mette Bech Risør, John Brandt Brodersen, Anders Stockmarr, Anna Bernhardt Lyhnebeck, Maarten Rozing, Sussi Friis Buhl, Ann-Kathrin Lindahl Christiansen, Jette Kristensen, John Sahl Andersen, Barbara Ann Barrett, Camilla Merrild, Frans Waldorff, Iben Charlotte Aamann, Jens Søndergård, Jette Kolding Kristensen, Katrine Tranberg Jensen, Kristine Bissenbakker, Mads Toft Kristensen, Maria Haahr Nielsen, Marius Brostrøm Kousgaard, Sanne Lykke Lundstrøm, Sidsel Böcher, Sofie Rosenlund Lau, Solvej Skriver Hansen, Zaza Kamper-Jørgensen

Publikováno v: BMJ Open, Vol 14, Iss 2 (2024)

Introduction Patients with complex multimorbidity face a high treatment burden and frequently have low quality of life. General practice is the key organisational setting in terms of offering people with complex multimorbidity integrated, longitudina

Externí odkaz: https://doaj.org/article/8aad408a96b9438fb2bc86a103ff16ac

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.

Autor: Melissa Paoloni, Christina Mazcko, Kimberly Selting, Susan Lana, Lisa Barber, Jeffrey Phillips, Katherine Skorupski, David Vail, Heather Wilson, Barbara Biller, Anne Avery, Matti Kiupel, Amy LeBlanc, Anna Bernhardt, Beatrice Brunkhorst, Robert Tighe, Chand Khanna

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0129954 (2015)

Interleukin (IL)-12 is a pro-inflammatory cytokine that mediates T-helper type 1 responses and cytotoxic T-cell activation, contributing to its utility as anti-cancer agent. Systemic administration of IL-12 often results in unacceptable toxicity; the

Externí odkaz: https://doaj.org/article/383cb812cca048fabf334e0bf18c85ea

Physiotherapists' Treatment Strategies and Delineation of Areas of Responsibility for People With Musculoskeletal Conditions and Comorbidities in Private Physiotherapy Practice: A Qualitative Study

Autor: Lyhnebeck, Anna Bernhardt, Risør, Mette Bech, Guassora, Ann Dorrit, Andersen, John Sahl, Skou, Søren Thorgaard

Publikováno v: Lyhnebeck, Risør, Guassora, Andersen, Skou. Physiotherapists' Treatment Strategies and Delineation of Areas of Responsibility for People With Musculoskeletal Conditions and Comorbidities in Private Physiotherapy Practice: A Qualitative Study. Musculoskeletal Care. 2024;22(4)

Externí odkaz: https://hdl.handle.net/10037/35394

The immunocytokine NHS-IL12 as a potential cancer therapeutic

Autor: Wilson Guzman, Helen Sabzevari, Robert Tighe, Giorgio Kradjian, Berend Neuteboom, John W. Greiner, Anna Bernhardt, Jeffrey Schlom, Yan Lan, Jonathan K. Fallon

Publikováno v: Oncotarget

// Jonathan Fallon 1,* , Robert Tighe 2,* , Giorgio Kradjian 2 , Wilson Guzman 2 , Anna Bernhardt 2 , Berend Neuteboom 2 , Yan Lan 2 , Helen Sabzevari 2 , Jeffrey Schlom 1 , John W. Greiner 1 1 Laboratory of Tumor Immunology and Biology, Center for C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd495cac2aae4d0dcc18b98ab2ad2fb
http://europepmc.org/articles/PMC4039112

Physiotherapists' Treatment Strategies and Delineation of Areas of Responsibility for People With Musculoskeletal Conditions and Comorbidities in Private Physiotherapy Practice: A Qualitative Study.

Autor: Lyhnebeck AB; The Research Unit and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.; The Research and Implementation Unit PROgrez, Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospital, Slagelse, Denmark., Risør MB; The Research Unit and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.; The Research Unit for General Practice, Department of Community Medicine, UiT the Arctic University of Norway, Tromsø, Norway., Guassora AD; The Research Unit and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Andersen JS; The Research Unit and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Skou ST; The Research and Implementation Unit PROgrez, Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospital, Slagelse, Denmark.; Research Unit for Musculoskeletal Function and Physiotherapy, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.

Publikováno v: Musculoskeletal care [Musculoskeletal Care] 2024 Dec; Vol. 22 (4), pp. e1941.