Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Anna B. Sunshine"'
Autor:
Monica R Sanchez, Aaron W Miller, Ivan Liachko, Anna B Sunshine, Bryony Lynch, Mei Huang, Erica Alcantara, Christopher G DeSevo, Dave A Pai, Cheryl M Tucker, Margaret L Hoang, Maitreya J Dunham
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006585 (2017)
Evolutionary outcomes depend not only on the selective forces acting upon a species, but also on the genetic background. However, large timescales and uncertain historical selection pressures can make it difficult to discern such important background
Externí odkaz:
https://doaj.org/article/99b13bdbe9b3403c95f09013dfc3ba3d
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006339 (2016)
High-throughput sequencing has enabled genetic screens that can rapidly identify mutations that occur during experimental evolution. The presence of a mutation in an evolved lineage does not, however, constitute proof that the mutation is adaptive, g
Externí odkaz:
https://doaj.org/article/e2b0a83de3084ae9bd0933834c27638b
Publikováno v:
PLoS Biology, Vol 13, Iss 5, p e1002155 (2015)
Aneuploidy is a hallmark of tumor cells, and yet the precise relationship between aneuploidy and a cell's proliferative ability, or cellular fitness, has remained elusive. In this study, we have combined a detailed analysis of aneuploid clones isolat
Externí odkaz:
https://doaj.org/article/97db6a30f658485f991773357087ab1f
Autor:
Alexey J. Merz, Daniel B. Carr, Brian M. Wasko, Giang T. Ong, Maitreya J. Dunham, Daniel P. Nickerson, Christopher J. Murakami, Matt Kaeberlein, Anna B. Sunshine, Anna Shemorry
Publikováno v:
Aging Cell
Summary Aneuploidy and aging are correlated; however, a causal link between these two phenomena has remained elusive. Here, we show that yeast disomic for a single native yeast chromosome generally have a decreased replicative lifespan. In addition,
Autor:
Giang T. Ong, Joseph C. Sanchez, M. K. Raghuraman, Sara C. Di Rienzi, Anna B. Sunshine, Maitreya J. Dunham, Celia Payen, Bonita J. Brewer, Jamie L. Pogachar
Publikováno v:
G3: Genes|Genomes|Genetics
Population adaptation to strong selection can occur through the sequential or parallel accumulation of competing beneficial mutations. The dynamics, diversity, and rate of fixation of beneficial mutations within and between populations are still poor
Autor:
Natasha Pashkova, Stanley C. Winistorfer, Robert C. Piper, Lokesh Gakhar, Maitreya J. Dunham, Liping Yu, Matthew S. Rich, Anna B. Sunshine
Publikováno v:
Developmental Cell. 25(5):520-533
SummarySorting of ubiquitinated membrane proteins into lumenal vesicles of multivesicular bodies is mediated by the Endosomal Sorting Complex Required for Transport (ESCRT) apparatus and accessory proteins such as Bro1, which recruits the deubiquitin
Autor:
Christopher G. DeSevo, Bryony Lynch, Monica R. Sanchez, Maitreya J. Dunham, Dave A. Pai, Ivan Liachko, Cheryl M. Tucker, Mei Huang, Anna B. Sunshine, Aaron W. Miller, Margaret L. Hoang
Evolutionary outcomes depend not only on the selective forces acting upon a species, but also on the genetic background. However, large timescales and uncertain historical selection pressures can make it difficult to discern such important background
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b5e445e4ce51b4431c272a2a59db9e
https://doi.org/10.1101/063248
https://doi.org/10.1101/063248
Autor:
Sarah Brice Russo, W. Scott Moye-Rowley, Maitreya J. Dunham, L. Ashley Cowart, Frédéric Devaux, Svetlana Khakhina, Raman Manoharlal, Corinne Blugeon, Sophie Lemoine, Soraya S. Johnson, Anna B. Sunshine
Publikováno v:
Eukaryotic Cell
Eukaryotic Cell, American Society for Microbiology, 2015, 14 (5), pp.442-453. ⟨10.1128/EC.00021-15⟩
Eukaryotic Cell, 2015, 14 (5), pp.442-453. ⟨10.1128/EC.00021-15⟩
Eukaryotic Cell, American Society for Microbiology, 2015, 14 (5), pp.442-453. ⟨10.1128/EC.00021-15⟩
Eukaryotic Cell, 2015, 14 (5), pp.442-453. ⟨10.1128/EC.00021-15⟩
ATP-binding cassette transporters Pdr5 and Yor1 from Saccharomyces cerevisiae control the asymmetric distribution of phospholipids across the plasma membrane as well as serving as ATP-dependent drug efflux pumps. Mutant strains lacking these transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504dbd2488323b0f065cf7d5d5f45100
https://hal.archives-ouvertes.fr/hal-01528527
https://hal.archives-ouvertes.fr/hal-01528527
Autor:
Mei Huang, Ivan Liachko, Monica R. Sanchez, Maitreya J. Dunham, Erica Alcantara, Aaron W. Miller, Margaret L. Hoang, Dave A. Pai, Cheryl M. Tucker, Anna B. Sunshine, Bryony Lynch, Christopher G. DeSevo
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006585 (2017)
PLoS Genetics
PLoS Genetics
Evolutionary outcomes depend not only on the selective forces acting upon a species, but also on the genetic background. However, large timescales and uncertain historical selection pressures can make it difficult to discern such important background
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 10, p e1006339 (2016)
PLoS Genetics, Vol 12, Iss 10, p e1006339 (2016)
High-throughput sequencing has enabled genetic screens that can rapidly identify mutations that occur during experimental evolution. The presence of a mutation in an evolved lineage does not, however, constitute proof that the mutation is adaptive, g