Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anna Březinová"'
Publikováno v:
Journal of Analytical Methods in Chemistry, Vol 2013 (2013)
The ability of LC-NMR to detect simultaneously free and conjugated phytosterols in natural extracts was tested. The advantages and disadvantages of a gradient HPLC-NMR method were compared to the fast composition screening using SEC-NMR method. Fract
Externí odkaz:
https://doaj.org/article/ca6a34d3644f4836a87938363409f0f4
Autor:
Mikhail Makarov, Lucie Bednárová, Jingwei Meng, A. Keith Dunker, Jiří Vondrášek, Klára Hlouchová, Vyacheslav Tretyachenko, Valerio Guido Giacobelli, Anna Březinová, Pavel Srb
Publikováno v:
Protein Sci
The wide variety of protein structures and functions results from the diverse properties of the 20 canonical amino acids. The generally accepted hypothesis is that early protein evolution was associated with enrichment of a primordial alphabet, there
Autor:
Tomáš Knedlík, Vladimir Subr, Pavel Šácha, Anna Březinová, Libor Kostka, Kristýna Blažková, Petra Dvořáková, Jan Konvalinka, Petr Šimon
Publikováno v:
ACS chemical biology. 13(12)
Identifying protein targets of bioactive small molecules often requires complex, lengthy development of affinity probes. We present a method for stochastic modification of small molecules of interest with a photoactivatable phenyldiazirine linker. Th
Autor:
Tomáš Strašák, Martin Bernard, Lucie Maixnerová, Lucie Červenková Št’astná, Radek Fajgar, Anna Březinová, Jindřich Karban
Publikováno v:
Journal of Organometallic Chemistry. 768:115-120
Substituted titanocene complexes have been prepared by hydrosilylation of organic substrates containing a terminal double bond by cyclopentadienyl complexes of titanium bearing a Si–H functional group. This new synthetic protocol is demonstrated by
Autor:
Anna Březinová, Josef Cvačka, Markéta Rybáčková, Mario Babuněk, Jaroslav Kvíčala, Ondřej Šimůnek, Jan Hošek
Publikováno v:
Journal of Fluorine Chemistry. 161:66-75
Second generation Grubbs catalyst was modified stepwise with perfluoroalkylated isopropoxystyrene and two perfluoroalkanoate or perfluoropolyoxaalkanoate ligands to afford heavy fluorous phosphine-free ruthenium complexes, which displayed high activi
Autor:
Jan Konvalinka, Petr Šimon, Libor Kostka, Petra Dvořáková, Pavel Šácha, Vladimir Subr, Tomáš Knedlík, Anna Březinová, Kristyna Blazkova
Publikováno v:
Cancer Immunology Research. 7:B147-B147
The renaissance of phenotypic screening leads to the discovery of biologically active small molecules resulting in a high need to quickly and efficiently identify their protein target. This is most commonly done by a preparation of an affinity probe
Autor:
Anna Březinová, Jan Konvalinka, Miroslava Blechová, Pavel Šácha, Frantisek Sedlak, Martin Šafařík, Jaroslav Šebestík
Publikováno v:
The FASEB Journal. 27:2626-2632
The accumulation of amyloid-β (Aβ) peptide is thought to be a major causative mechanism of Alzheimer's disease. Aβ accumulation could be caused by dysregulated processing of amyloid precursor protein, yielding excessive amounts of Aβ, and/or by i
Autor:
Jaroslav Šebestík, Zbigniew Zawada, Petr Bouř, Anna Březinová, Karel Holada, Eva Dvořáková, Martin Šafařík, Ivan Stibor, Olga Janouskova, Jan Hlaváček
Publikováno v:
Amino Acids. 44:1279-1292
Quinacrine is a drug that is known to heal neuronal cell culture infected with prions, which are the causative agents of neurodegenerative diseases called transmissible spongiform encephalopathies. However, the drug fails when it is applied in vivo.
Autor:
Martin Skalický, Anna Březinová, Jaroslav Kvíčala, Magdalena Kvíčalová, Jana Paterová, Josef Cvačka, Markéta Rybáčková, Veronika Skalická
Publikováno v:
Organometallics. 31:1524-1532
A series of fluorous silver complexes bearing two fluorous NHC ligands was synthesized from bis(polyfluoroalkylated) or bis(polyfluoropolyoxaalkylated) imidazolium salts and silver oxide in acetoni...
Autor:
Jaroslav Kvíčala, Magdalena Kvíčalová, Josef Cvačka, Veronika Skalická, Markéta Rybáčková, Anna Březinová, Martin Skalický, Jan Čejka
Publikováno v:
Journal of Fluorine Chemistry. 132:434-440
Tripyrazolylmethanes represent a novel class of uncharged ligands analogous to charged tripyrazolylborates (scorpionates), which are isoelectronic and isolobal with cyclopentadienides. We report here a straightforward synthesis of the first polyfluor