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pro vyhledávání: '"Anna Bäcksbro-Saeidi"'
Autor:
Anna Bäcksbro-Saeidi, Sandra Gordon, Peter Agback, Bo Carlsson, Konrad F. Koehler, Peter Brandt, Stefan Rehnmark, Theresa Apelqvist, Johan Malm, Mathias Färnegårdh, Gary J. Grover, William Nelson, Marlena Grynfarb
Publikováno v:
Journal of Medicinal Chemistry. 49:6635-6637
A new high-affinity thyroid hormone antagonist 6 with druglike properties was designed and synthesized. The compound behaved as an antagonist in a cell transactivation assay, and in a first in vivo experiment in rats.