Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anna Appios"'
Autor:
Jake R. Thomas, Anna Appios, Emily F. Calderbank, Nagisa Yoshida, Xiaohui Zhao, Russell S. Hamilton, Ashley Moffett, Andrew Sharkey, Elisa Laurenti, Courtney W. Hanna, Naomi McGovern
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The generation of primitive macrophages remains a poorly understood process in humans. Here, the authors identify placental erythro-myeloid progenitors that give rise to foetal macrophages in the early human placenta and demonstrate that epigenetic s
Externí odkaz:
https://doaj.org/article/370741294d1d45e496cf44e8daffe8d6
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The placenta is a fetal-derived organ whose function is crucial for both maternal and fetal health. The human placenta contains a population of fetal macrophages termed Hofbauer cells. These macrophages play diverse roles, aiding in placental develop
Externí odkaz:
https://doaj.org/article/fc3abb97d96242d0b377e105cb58e701
Publikováno v:
Bio-Protocol, Vol 11, Iss 11 (2021)
The placenta is the crucial organ that regulates the health of both mother and fetus during pregnancy. The human placenta is composed of villous tree-like structures that embed into the maternal decidua. Within the stroma of the villi resides a popul
Externí odkaz:
https://doaj.org/article/715a6f3c699c4ca3a0d3b28fe78f7474
Localized immune surveillance of primary melanoma in the skin deciphered through executable modeling
Autor:
Rowan Howell, James Davies, Matthew A. Clarke, Anna Appios, Inês Mesquita, Yashoda Jayal, Ben Ringham-Terry, Isabel Boned Del Rio, Jasmin Fisher, Clare L. Bennett
Publikováno v:
Science Advances. 9
While skin is a site of active immune surveillance, primary melanomas often escape detection. Here, we have developed an in silico model to determine the local cross-talk between melanomas and Langerhans cells (LCs), the primary antigen-presenting ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8bafc2eb66cf9196d48018d1e75c375
https://doi.org/10.1126/sciadv.add1992
https://doi.org/10.1126/sciadv.add1992
Autor:
Jake R. Thomas, Anna Appios, Emily F. Calderbank, Xiaohui Zhao, Russell S. Hamilton, Ashley Moffett, Andrew Sharkey, Elisa Laurenti, Naomi McGovern
The earliest macrophages are generated during embryonic development from erythro-myeloid progenitors (EMPs) via primitive haematopoiesis. This process is still poorly understood in humans but is generally thought to be spatially restricted to the yol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51aa24c677d1b5851891ab19857ecb30
https://doi.org/10.1101/2022.02.26.482080
https://doi.org/10.1101/2022.02.26.482080
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
The placenta is a fetal-derived organ whose function is crucial for both maternal and fetal health. The human placenta contains a population of fetal macrophages termed Hofbauer cells. These macrophages play diverse roles, aiding in placental develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa9e510c1a0b55d16c6ccc4130a2119
https://doi.org/10.3389/fimmu.2021.771054
https://doi.org/10.3389/fimmu.2021.771054
Autor:
Ian Jackson, Graham M. Lord, Jenifer Sanchez, Richard G. Jenner, Omer Serhan Omer, Rimma Goldberg, Luke B. Roberts, Natalie J. Prescott, Jennie Clough, Nedyalko Petrov, Peter M. Irving, Anna Appios, Shahram Kordasti, Miles Parkes, Arnulf Hertweck, Scott David Tasker, Anna Lorenc
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims Differential responsiveness to interleukin [IL]-2 between effector CD4+ T cells [Teff] and regulatory T cells [Treg] is a fundamental mechanism of immunoregulation. The single nucleotide polymorphism [SNP] rs61839660, located with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc64403c7a121fe6015b638a389d8d86
https://pubmed.ncbi.nlm.nih.gov/34120187
https://pubmed.ncbi.nlm.nih.gov/34120187
Autor:
Colin Lee, Russell S. Hamilton, Bing Liu, Praveena Naidu, Christopher H. T. Lee, Anna Appios, Florent Ginhoux, Joana Cerveira, Graham J. Burton, Maria Donde, Andrew M. Sharkey, Ashley Moffett, Xiaohui Zhao, Roksana Dutkiewicz, Naomi McGovern, Jake R. Thomas
Publikováno v:
Journal of Experimental Medicine. 218
Hofbauer cells (HBCs) are a population of macrophages found in high abundance within the stroma of the first-trimester human placenta. HBCs are the only fetal immune cell population within the stroma of healthy placenta. However, the functional prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b27ecd5e787081ca31db40fca13ade67
https://doi.org/10.1084/jem.20200891
https://doi.org/10.1084/jem.20200891
Autor:
Bing Liu, Anna Appios, Ashley Moffett, Jake R. Thomas, Florent Ginhoux, Russell S. Hamilton, Roksana Dutkiewicz, Graham J. Burton, Joana Cerveira, Praveena Naidu, Andrew M. Sharkey, Naomi McGovern, Christopher H. T. Lee, Colin Lee, Xiaohui Zhao, Maria Donde
Hofbauer cells (HBC) are a population of macrophages found in high abundance within the stroma of the first trimester human placenta. HBC are the only fetal immune cell population within the stroma of healthy placenta. However, the functional propert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff282df86f482a28bcbbea63c9cb318c
https://doi.org/10.1101/2020.09.03.279919
https://doi.org/10.1101/2020.09.03.279919