Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anna Alexanova"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Metabolic dysfunction, partly driven by altered liver function, predisposes to coronary artery disease (CAD), but the role of liver in vulnerable atherosclerotic plaque development remains unclear. Here we produced hepatocyte-like cells (HLC
Externí odkaz:
https://doaj.org/article/a59d60494e114422b480f9913979936d
Autor:
Disheet Shah, Chandra Prajapati, Kirsi Penttinen, Reeja Maria Cherian, Jussi T. Koivumäki, Anna Alexanova, Jari Hyttinen, Katriina Aalto-Setälä
Publikováno v:
Cells, Vol 9, Iss 5, p 1153 (2020)
Mutations in the HERG gene encoding the potassium ion channel HERG, represent one of the most frequent causes of long QT syndrome type-2 (LQT2). The same genetic mutation frequently presents different clinical phenotypes in the family. Our study aime
Externí odkaz:
https://doaj.org/article/efc99e4fd8904ee387f690491ee62611
Autor:
Dimple Kauhanen, Leena E. Viiri, Kim Ekroos, Mostafa Kiamehr, Laura Heiskanen, Reijo Käkelä, Anna Alexanova, Reijo Laaksonen, Terhi Vihervaara, Katriina Aalto-Setälä
Publikováno v:
Journal of Cellular Physiology. 234:3744-3761
Hepatocyte-like cells (HLCs) differentiated from human-induced pluripotent stem cells offer an alternative platform to primary human hepatocytes (PHHs) for studying the lipid metabolism of the liver. However, despite their great potential, the lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84016418a56bb534150cd6f882dca077
https://doi.org/10.1002/jcp.27131
https://doi.org/10.1002/jcp.27131
Publikováno v:
Atherosclerosis. 331:e220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58ada68a234906e84e575236d16d4c21
https://doi.org/10.1016/j.atherosclerosis.2021.06.675
https://doi.org/10.1016/j.atherosclerosis.2021.06.675
Autor:
Henri Niskanen, Mikko Oittinen, Tommi Rantapero, Minna U. Kaikkonen, Keijo Viiri, Leena E. Viiri, Katriina Aalto-Setälä, Anna Alexanova, Matti Nykter, Mostafa Kiamehr
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Hepatocyte-like cells (HLCs) derived from induced pluripotent stem cells (iPSCs) provide a renewable source of cells for drug discovery, disease modelling and cell-based therapies. Here, by using GRO-Seq we provide the first genome-wide analysis of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea73c25b864e2c8a8d4ffd1821d72b7a
Publikováno v:
Atherosclerosis. 287:e118-e119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28b2a64ad174d0bd87b0ab7c9413545b
https://doi.org/10.1016/j.atherosclerosis.2019.06.344
https://doi.org/10.1016/j.atherosclerosis.2019.06.344