Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anna Adamska‐Bartłomiejczyk"'
Autor:
Katarzyna Gach-Janczak, Monika Biernat, Mariola Kuczer, Anna Adamska-Bartłomiejczyk, Alicja Kluczyk
Publikováno v:
Molecules, Vol 29, Iss 7, p 1544 (2024)
Pain affects one-third of the global population and is a significant public health issue. The use of opioid drugs, which are the strongest painkillers, is associated with several side effects, such as tolerance, addiction, overdose, and even death. A
Externí odkaz:
https://doaj.org/article/27b7829e489e4675a8f0a5fc3a37e8f4
Autor:
Karol Wtorek, Piotr F. J. Lipiński, Anna Adamska-Bartłomiejczyk, Justyna Piekielna-Ciesielska, Jarosław Sukiennik, Alicja Kluczyk, Anna Janecka
Publikováno v:
Molecules, Vol 27, Iss 1, p 151 (2021)
Our formerly described pentapeptide opioid analog Tyr-c[D-Lys-Phe-Phe-Asp]NH2 (designated RP-170), showing high affinity for the mu (MOR) and kappa (KOR) opioid receptors, was much more stable than endomorphine-2 (EM-2) in the rat brain homogenate an
Externí odkaz:
https://doaj.org/article/c146faeb9cb8454185fcfe4226b71699
Autor:
Alicja Kluczyk, Anna Adamska-Bartłomiejczyk, Anna Janecka, Piotr F. J. Lipiński, Justyna Piekielna-Ciesielska
Publikováno v:
ChemMedChem. 15:1322-1329
Peptide-based agonists of the μ opioid receptor (μOR) are promising therapeutic candidates for pain relief with reduced side effects compared to morphine. A deep understanding of μOR-ligand interactions is necessary for future design of peptide-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a2386fcef66127d59e353a62b605b7
https://doi.org/10.1002/cmdc.202000248
https://doi.org/10.1002/cmdc.202000248
Autor:
Karol Wtorek, Alessia Ghidini, Luca Gentilucci, Anna Adamska-Bartłomiejczyk, Justyna Piekielna-Ciesielska, Chiara Ruzza, Chiara Sturaro, Girolamo Calò, Stefano Pieretti, Alicja Kluczyk, John McDonald, David G. Lambert, Anna Janecka
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 20; Pages: 12700
Recently, mixed opioid/NOP agonists came to the spotlight for their favorable functional profiles and promising outcomes in clinical trials as novel analgesics. This study reports on two novel chimeric peptides incorporating the fragment Tyr-c[D-Lys-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c952bd506bc065eaeb9ec43ae71ec84
https://hdl.handle.net/11585/904457
https://hdl.handle.net/11585/904457
Autor:
Girolamo Calo, Anna Janecka, Joanna Piasecka-Zelga, Karol Wtorek, Justyna Piekielna-Ciesielska, Katarzyna Gach-Janczak, Anna Adamska-Bartłomiejczyk, Agata Szymaszkiewicz, Federica Ferrari
Publikováno v:
Peptides. 105:51-57
Morphine and related drugs, which are the most effective analgesics for the relief of severe pain, act through activating opioid receptors. The endogenous ligands of these receptors are opioid peptides which cannot be used as antinociceptive agents d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b7c07eb873f5e85e0c870eecf47f0b
https://doi.org/10.1016/j.peptides.2018.04.014
https://doi.org/10.1016/j.peptides.2018.04.014
Autor:
Anna Adamska-Bartłomiejczyk, Alicja Kluczyk, Justyna Piekielna-Ciesielska, Anna Janecka, Szabolcs Dvorácskó, Grzegorz Wołczański, Marek Lisowski, Attila Borics, Csaba Tömböly
Publikováno v:
Journal of Peptide Science. 23:864-870
Three novel morphiceptin analogs, in which Pro in position 2 and/or 4 was replaced by cis-4-aminoproline connected with the preceding amino acid through the primary amino group, were synthesized. The opioid receptor affinities, functional assay resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::789b6d1c32442be12456ce8b3b5bdfda
https://doi.org/10.1002/psc.3050
https://doi.org/10.1002/psc.3050
Autor:
Anna Janecka, Girolamo Calo, Joanna Piasecka-Zelga, Chiara Ruzza, Federica Ferrari, Alicja Kluczyk, Justyna Piekielna-Ciesielska, Karol Wtorek, Anna Adamska-Bartłomiejczyk
Publikováno v:
Molecules
Volume 24
Issue 24
Volume 24
Issue 24
Morphine, which acts through opioid receptors, is one of the most efficient analgesics for the alleviation of severe pain. However, its usefulness is limited by serious side effects, including analgesic tolerance, constipation, and dependence liabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c412ac66ccb43989202b56cbc27e85
http://hdl.handle.net/11577/3386361
http://hdl.handle.net/11577/3386361
Autor:
Magdalena Białek-Pietras, Jolanta D. Żołnierczyk, Katarzyna Bednarska, Zofia Sulowska, Adam Mieczkowski, Edyta Paradowska, Agnieszka B. Olejniczak, Zbigniew J. Lesnikowski, Mirosława Studzińska, Zofia M. Kiliańska, Anna Adamska‐Bartłomiejczyk
Publikováno v:
Boron-Based Compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e7bdbc8bfd6dfd35d534e44d9c6bb2
https://doi.org/10.1002/9781119275602.ch1.2
https://doi.org/10.1002/9781119275602.ch1.2
Autor:
Katarzyna, Gach-Janczak, Justyna, Piekielna-Ciesielska, Anna, Adamska-Bartłomiejczyk, Karol, Wtorek, Federica, Ferrari, Girolamo, Calo', Agata, Szymaszkiewicz, Joanna, Piasecka-Zelga, Anna, Janecka
Publikováno v:
Peptides. 105
Morphine and related drugs, which are the most effective analgesics for the relief of severe pain, act through activating opioid receptors. The endogenous ligands of these receptors are opioid peptides which cannot be used as antinociceptive agents d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc6eff3235a9f4e963f58a31b001c349
https://pubmed.ncbi.nlm.nih.gov/29684591
https://pubmed.ncbi.nlm.nih.gov/29684591
Autor:
Anna, Adamska-Bartłomiejczyk, Attila, Borics, Csaba, Tömböly, Szabolcs, Dvorácskó, Marek, Lisowski, Alicja, Kluczyk, Grzegorz, Wołczański, Justyna, Piekielna-Ciesielska, Anna, Janecka
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 23(12)
Three novel morphiceptin analogs, in which Pro in position 2 and/or 4 was replaced by cis-4-aminoproline connected with the preceding amino acid through the primary amino group, were synthesized. The opioid receptor affinities, functional assay resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ae6248d4b0bc2125d1f95d0b14e979b
https://pubmed.ncbi.nlm.nih.gov/29110363
https://pubmed.ncbi.nlm.nih.gov/29110363