Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anna A. S. Tang"'
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1040 (2024)
Src homology 3 (SH3) domains play a critical role in mediating protein–protein interactions (PPIs) involved in cell proliferation, migration, and the cytoskeleton. Despite their abundance in the human proteome, the functions and molecular interacti
Externí odkaz:
https://doaj.org/article/09656d7271eb4a709813154e06a09ec5
Autor:
Francine Parker, Anna A. S. Tang, Brendan Rogers, Glenn Carrington, Cris dos Remedios, Amy Li, Darren Tomlinson, Michelle Peckham
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Dilated Cardiomyopathy is a common form of heart failure. Determining how this disease affects the structure and organization of cardiomyocytes in the human heart is important in understanding how the heart becomes less effective at contraction. Here
Externí odkaz:
https://doaj.org/article/cc6a0c4d5c4f4d3485748c72de4d581d
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2247
Artificial binding proteins have been validated as alternatives to antibodies in their use as research reagents in molecular and cellular biology. For example, they have been used as inhibitors of protein-protein interactions to modulate activity, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eaf0a8cd2a9df375e1551f975b1fe515
https://pubmed.ncbi.nlm.nih.gov/33301114
https://pubmed.ncbi.nlm.nih.gov/33301114
Autor:
Christian, Tiede, Anna A S, Tang, Sarah E, Deacon, Upasana, Mandal, Joanne E, Nettleship, Robin L, Owen, Suja E, George, David J, Harrison, Raymond J, Owens, Darren C, Tomlinson, Michael J, McPherson
Publikováno v:
Protein Engineering, Design and Selection
We have designed a novel non-antibody scaffold protein, termed Adhiron, based on a phytocystatin consensus sequence. The Adhiron scaffold shows high thermal stability (Tm ca. 101°C), and is expressed well in Escherichia coli. We have determined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48b78cdce954d2b6883de9099f614c5a
https://pubmed.ncbi.nlm.nih.gov/24668773
https://pubmed.ncbi.nlm.nih.gov/24668773