Revealing molecular mechanisms of early-onset tongue cancer by spatial transcriptomics

Autor: Marina R. Patysheva, Elena S. Kolegova, Anna A. Khozyainova, Elizaveta A. Prostakishina, Vyacheslav Y. Korobeynikov, Maxim E. Menyailo, Pavel S. Iamshchikov, Dmitry M. Loos, Oleg I. Kovalev, Marina V. Zavyalova, Irina K. Fedorova, Denis E. Kulbakin, Irina V. Larionova, Andrey P. Polyakov, Liliya P. Yakovleva, Mikhail A. Kropotov, Natalya S. Sukortseva, Yusheng Lu, Lee Jia, Rohit Arora, Evgeny L. Choinzonov, Pinaki Bose, The Consortium Etiology and Pathogenesis of Oral Cancer in Young Adults, Evgeny V. Denisov

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract Tongue cancer at a young age demonstrates an increase in incidence, aggressiveness, and poor response to therapy. Classic etiological factors for head and neck tumors such as tobacco, alcohol, and human papillomavirus are not related to earl

Externí odkaz: https://doaj.org/article/109273e1e0924625a83bb97d8557a989

Prognosis of Different Types of Non-Small Cell Lung Cancer Progression: Current State and Perspectives

Autor: Anastasia A. Schegoleva, Anna A. Khozyainova, Anton A. Fedorov, Tatiana S. Gerashchenko, Evgeny O. Rodionov, Evgeny B. Topolnitsky, Nikolay A. Shefer, Olga V. Pankova, Anastasia A. Durova, Marina V. Zavyalova, Vladimir M. Perelmuter, Evgeny V. Denisov

Publikováno v: Cellular Physiology and Biochemistry, Vol 55, Iss S2, Pp 29-48 (2021)

Externí odkaz: https://doaj.org/article/47a6a45f442c4f749900b0516c2cc182

Metastasis Prevention: Focus on Metastatic Circulating Tumor Cells

Autor: Anna A Khozyainova, Evgeny V. Denisov, Ustinia A Bokova, Elena E Ivanyuk, Maxim E Menyailo

Publikováno v: Molecular Diagnosis & Therapy. 25:549-562

Metastasis is the main cause of cancer death. Metastatic foci are derived from tumor cells that detach from the primary tumor and then enter the circulation. Circulating tumor cells (CTCs) are generally associated with a high probability of distant m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e728bd7762f48dad6770f0109517345a
https://doi.org/10.1007/s40291-021-00543-5

Heterogeneity of circulating epithelial cells in breast cancer at single-cell resolution: identifying tumor and hybrid cells

Autor: Liubov A. Tashireva, Maxim E Menyailo, Evgeny V. Denisov, Sofia Yu. Zolotareva, Anna A. Khozyainova, Vladimir V. Alifanov, Nataliya O. Popova, Evgeny L. Choinzonov, Tatiana S. Gerashchenko, Viktoria R. Zainullina, V. M. Perelmuter, Nadezhda V. Cherdyntseva, Nataliya A. Tarabanovskaya, Evgeniya S. Grigoryeva, Olga E. Savelieva

Circulating tumor cells and hybrid cells formed by the fusion of tumor cells with normal cells are leading players in metastasis and have prognostic relevance. Circulating tumor cells and hybrid cells are identified as CD45-negative and CD45-positive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d278219a831e6064bee480c5e57ad0b0
https://doi.org/10.1101/2021.11.24.469962

Whole-exome sequencing reveals an association of rs112065068 in TGOLN2 gene with distant metastasis of non-small cell lung cancer.

Autor: Gerashchenko T; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia; Laboratory of Single Cell Biology, Research Institute of Molecular and Cellular Medicine, Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya Str. 6, Moscow 117198, Russia., Skitchenko R; ITMO, Kronverksky Pr. 49, Bldg. A, St. Petersburg, 197101, Russia., Korobeynikova A; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia; Laboratory of Single Cell Biology, Research Institute of Molecular and Cellular Medicine, Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya Str. 6, Moscow 117198, Russia., Kuanysheva K; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia., Khozyainova A; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia., Vorobiev R; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia., Rodionov E; Department of Thoracic Oncology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia., Miller S; Department of Thoracic Oncology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia., Topolnitsky E; Department of Surgery with a Course of Mobilization Training and Disaster Medicine, Siberian State Medical University, Moskovskiy Tract 2, Tomsk 634050, Russia., Shefer N; Department of Surgery with a Course of Mobilization Training and Disaster Medicine, Siberian State Medical University, Moskovskiy Tract 2, Tomsk 634050, Russia., Anisimenko M; Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Ac. Lavrentieva Ave. 10, Novosibirsk 630090, Russia., Zhuikova L; Laboratory of Epidemiology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia., Vashisth M; Tomsk State University, Lenina Ave. 36, Tomsk 634050, Russia., Pankova O; Department of General and Molecular Pathology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia., Perelmuter V; Department of General and Molecular Pathology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia., Rezapova V; ITMO, Kronverksky Pr. 49, Bldg. A, St. Petersburg, 197101, Russia; University Cote D'Azur, Grand Château 28 Avenue de Valrose, Nice 06103, France., Artomov M; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43205, USA; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH 43215, USA., Denisov E; Laboratory of Cancer Progression Biology, Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Kooperativny Str. 5, Tomsk 634009, Russia; Laboratory of Single Cell Biology, Research Institute of Molecular and Cellular Medicine, Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya Str. 6, Moscow 117198, Russia. Electronic address: d_evgeniy@oncology.tomsk.ru.

Publikováno v: Gene [Gene] 2024 Aug 20; Vol. 920, pp. 148507. Date of Electronic Publication: 2024 Apr 24.