Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Anna A. Belkina"'
Publikováno v:
Consilium Medicum, Vol 26, Iss 11, Pp 752-758 (2024)
Current approaches to treating multiple sclerosis aim at controlling disease activity. Despite the variety of agents that have proven their effectiveness and were introduced in practice in the last decade, the use of the interferon β group remains r
Externí odkaz:
https://doaj.org/article/ba3ee63b13934f50a5ec31d57c690f99
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 17, Iss 2, Pp 65-74 (2023)
Demyelinating diseases of the central nervous system and multiple sclerosis in particular are a pressing issue for medical community and society as a whole. Deve- lopment and implementation of highly effective specific therapy significantly slow the
Externí odkaz:
https://doaj.org/article/00920ebcd2fc4cd1b7de337c8fff5ee7
Autor:
Victoria L. M. Herrera, Allan J. Walkey, Mai Q. Nguyen, Christopher M. Gromisch, Julie Z. Mosaddhegi, Matthew S. Gromisch, Bakr Jundi, Soeren Lukassen, Saskia Carstensen, Ridiane Denis, Anna C. Belkina, Rebecca M. Baron, Mayra Pinilla-Vera, Meike Mueller, W. Taylor Kimberly, Joshua N. Goldstein, Irina Lehmann, Angela R. Shih, Roland Eils, Bruce D. Levy, Nelson Ruiz-Opazo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-24 (2022)
Abstract Neutrophil-mediated secondary tissue injury underlies acute respiratory distress syndrome (ARDS) and progression to multi-organ-failure (MOF) and death, processes linked to COVID-19-ARDS. This secondary tissue injury arises from dysregulated
Externí odkaz:
https://doaj.org/article/e3433c566fb14028b1c283831cb361bc
Autor:
Kim Vanuytsel, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, Zhe Wang, Wilfredo F. Garcia-Beltran, Vladimir Vrbanac, Dylan Parsons, Evan C. Lam, Taylor M. Matte, Todd W. Dowrey, Sara S. Kumar, Mengze Li, Feiya Wang, Anthony K. Yeung, Gustavo Mostoslavsky, Ruben Dries, Joshua D. Campbell, Anna C. Belkina, Alejandro B. Balazs, George J. Murphy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
During human embryonic development, haematopoietic stem cells of the foetal liver undergo expansion, while retaining engraftment capacity. Here the authors apply CITE-seq to profile single cells from a human foetal liver, identifying a molecular sign
Externí odkaz:
https://doaj.org/article/cac11a57fa10405ca22f6fddb6df2365
Autor:
Anukul T. Shenoy, Carolina Lyon De Ana, Emad I. Arafa, Isabelle Salwig, Kimberly A. Barker, Filiz T. Korkmaz, Aditya Ramanujan, Neelou S. Etesami, Alicia M. Soucy, Ian M. C. Martin, Brian R. Tilton, Anne Hinds, Wesley N. Goltry, Hasmeena Kathuria, Thomas Braun, Matthew R. Jones, Lee J. Quinton, Anna C. Belkina, Joseph P. Mizgerd
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The maintenance of T resident memory (TRM) cells within pulmonary tissues is incompletely understood. Here the authors show that antigen presentation by lung epithelial cells maintains function and phenotype of pulmonary TRM cells within specific loc
Externí odkaz:
https://doaj.org/article/c4c893d49d55411c8e49e957418469ec
Autor:
Emad I. Arafa, Anukul T. Shenoy, Kimberly A. Barker, Neelou S. Etesami, Ian M.C. Martin, Carolina Lyon De Ana, Elim Na, Christine V. Odom, Wesley N. Goltry, Filiz T. Korkmaz, Alicia K. Wooten, Anna C. Belkina, Antoine Guillon, E. Camilla Forsberg, Matthew R. Jones, Lee J. Quinton, Joseph P. Mizgerd
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Recovery from pneumococcal pneumonia remodels the pool of alveolar macrophages so that they exhibit new surface marker profiles, transcriptomes, metabolomes, and responses to infection. Mechanisms mediating alveolar macrophage phenotypes after pneumo
Externí odkaz:
https://doaj.org/article/010788fe07a74054bdcc06f35fc12205
Autor:
Anna C. Belkina, Christopher O. Ciccolella, Rina Anno, Richard Halpert, Josef Spidlen, Jennifer E. Snyder-Cappione
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Visualisation tools that use dimensionality reduction, such as t-SNE, provide poor visualisation on large data sets of millions of observations. Here the authors present opt-SNE, that automatically finds data set-tailored parameters for t-SNE to opti
Externí odkaz:
https://doaj.org/article/e5126a248205487bb5a7c54c11c0bcc3
Autor:
Rachel R. Yuen, Dylan Steiner, Riley M.F. Pihl, Elizabeth Chavez, Alex Olson, Erika L. Smith, Lillia A. Baird, Filiz Korkmaz, Patricia Urick, Manish Sagar, Jacob L. Berrigan, Suryaram Gummuluru, Ronald B. Corley, Karen Quillen, Anna C. Belkina, Gustavo Mostoslavsky, Ian R. Rifkin, Yachana Kataria, Amedeo J. Cappione, Wenda Gao, Nina H. Lin, Nahid Bhadelia, Jennifer E. Snyder-Cappione
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The COVID-19 pandemic has drastically impacted work, economy, and way of life. Sensitive measurement of SARS-CoV-2 specific antibodies would provide new insight into pre-existing immunity, virus transmission dynamics, and the nuances of SARS-CoV-2 pa
Externí odkaz:
https://doaj.org/article/a872479249714dd78bd7bc72df044446
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101765- (2020)
Summary: White adipose tissue (WAT) is a dynamic tissue, which responds to environmental stimuli and dietary cues by changing its morphology and metabolic capacity. The ability of WAT to undergo a beige remodeling has become an appealing strategy to
Externí odkaz:
https://doaj.org/article/c98a115f0377415b8b8645936aed1af6
Autor:
Hisashi Akiyama, Caitlin M. Miller, Chelsea R. Ettinger, Anna C. Belkina, Jennifer E. Snyder-Cappione, Suryaram Gummuluru
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Type I Interferon is thought to be a driving force for immune activation and T cell exhaustion during HIV infection. Here the authors show that intron-containing HIV RNA induces innate immune activation resulting in associated T cell dysfunction.
Externí odkaz:
https://doaj.org/article/fd9ffab4b9f44e5a8e33aca631a09672