Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Anna A. Rybczynska"'
Autor:
T. Jeroen N. Hiltermann, Pei Meng, Jiacong Wei, Martijn Terpstra, Ali Saber, Klaas Kok, Wim Timens, Ed Schuuring, Jantine Sietzema, Anna A. Rybczynska, Anke van den Berg, Anthonie J. van der Wekken, Harry J.M. Groen
Publikováno v:
Cancers, 12(10):2843, 1-17. MDPI AG
Cancers
Cancers, Vol 12, Iss 2843, p 2843 (2020)
Volume 12
Issue 10
Cancers
Cancers, Vol 12, Iss 2843, p 2843 (2020)
Volume 12
Issue 10
The number of genomic aberrations known to be relevant in making therapeutic decisions for non-small cell lung cancer patients has increased in the past decade. Multiple molecular tests are required to reliably establish the presence of these aberrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b5e17d1f1fe57232441f9bb65128a4
https://research.rug.nl/en/publications/751e2ec5-d5cf-445d-b5d0-85ecf93b2ead
https://research.rug.nl/en/publications/751e2ec5-d5cf-445d-b5d0-85ecf93b2ead
Autor:
Kiichi Ishiwata, Chantal Kwizera, Csaba Nyakas, Nisha K. Ramakrishnan, Aren van Waarde, Rudi Dierckx, Jurgen W. A. Sijbesma, Anniek K. D. Visser, Anna A. Rybczynska, Paul G.M. Luiten, Philip H. Elsinga
Publikováno v:
Molecular Imaging and Biology
Molecular Imaging and Biology, 18(4), 588-597. SPRINGER
Molecular Imaging and Biology, 18(4), 588-597. SPRINGER
Purpose Sigma-1 receptor ligands modulate the release of several neurotransmitters and intracellular calcium signaling. We examined the binding of a radiolabeled sigma-1 agonist in the aging rat brain with positron emission tomography (PET). Procedur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8afab9f5729de974cfdf1e5d79ea8ea
https://doi.org/10.1007/s11307-015-0917-6
https://doi.org/10.1007/s11307-015-0917-6
Autor:
Rudi Dierckx, Philip H. Elsinga, Nisha Kuzhuppilly Ramakrishnan, Kiichi Ishiwata, Aren van Waarde, Anna A. Rybczynska
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1848(10):2703-2714
Sigma receptors (sigma-1 and sigma-2) represent two independent classes of proteins. Their endogenous ligands may include the hallucinogen N,N-dimethyltryptamine (DMT) and sphingolipid-derived amines which interact with sigma-1 receptors, besides ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525ec018dd1938743c25d00abf4b9c1c
Autor:
Aren van Waarde, Walter Noordzij, Rudi Dierckx, Hendrikus H. Boersma, Jourik A. Gietema, Anna A. Rybczynska, Steven de Jong, Philip H. Elsinga
Publikováno v:
Medicinal Research Reviews
Successful treatment of cancer patients requires balancing of the dose, timing, and type of therapeutic regimen. Detection of increased cell death may serve as a predictor of the eventual therapeutic success. Imaging of cell death may thus lead to ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62de53c819b55ccaf4867200c15a93e3
https://pubmed.ncbi.nlm.nih.gov/29528513
https://pubmed.ncbi.nlm.nih.gov/29528513
Autor:
A. J. van der Wekken, Ed Schuuring, Harry J.M. Groen, Jiacong Wei, M. M. Terpstra, Thijo J N Hiltermann, Ali Saber, Wim Timens, Klaas Kok, A.M. van den Berg, Anna A. Rybczynska
Publikováno v:
Annals of Oncology, 28. Oxford University Press
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37629350a05205b87616cc0443e6ecc7
https://doi.org/10.1093/annonc/mdx508.023
https://doi.org/10.1093/annonc/mdx508.023
Autor:
Rudi Dierckx, Lachlan S. Campbell-Verduyn, Philippus Elsinga, Bernard Feringa, Anna A. Rybczynska, Leila Mirfeizi, Aren van Waarde
Publikováno v:
Nuclear Medicine and Biology, 41(2), 203-209. ELSEVIER SCIENCE INC
Cerebral β‐adrenergic receptors (β‐ARs) play important roles in normal brain and changes of β-AR expression are associated with several neuropsychiatric illnesses. Given the high density of β‐AR in several brain regions, quantification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e1081b3c8942e112f281e899ff0a38
https://doi.org/10.1016/j.nucmedbio.2013.10.011
https://doi.org/10.1016/j.nucmedbio.2013.10.011
Autor:
A. J. van der Wekken, Klaas Kok, Thijo J N Hiltermann, Pei Meng, A. P. van den Berg, Anna A. Rybczynska, Ed Schuuring, Wim Timens, Harry J.M. Groen, Jiacong Wei, M. M. Terpstra
Publikováno v:
Annals of Oncology, 30:UNSP mdz413.025. Oxford University Press
Background The detection of driver aberrations such as EGFR and ALK, in tumour tissue or plasma has become important for treating lung cancer patients. The aim of this study is to explore the feasibility of detecting therapy-guiding aberrations in RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff30e9f6f50f3f89cc1203a193736ed
https://doi.org/10.1093/annonc/mdz413.025
https://doi.org/10.1093/annonc/mdz413.025
Autor:
Harry J.M. Groen, Jiacong Wei, Anthonie J. van der Wekken, Klaas Kok, Jeroen Hiltermann, Anke van den Berg, Anna A. Rybczynska, Pei Meng, Ed Schuuring, Martijn Terpstra
Publikováno v:
Cancer Research. 79:2989-2989
Background. In the past decade, treatment of advanced stage lung cancer patients guided by somatic aberrations has become routine practice. Different molecular tests are being applied to detect all targetable mutations and fusions. However, in most c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b2b0983fd0ad61efd5189daffd8ad84
https://doi.org/10.1158/1538-7445.am2019-2989
https://doi.org/10.1158/1538-7445.am2019-2989
Autor:
Johan R. de Jong, Rudi Dierckx, Nisha Kuzhuppilly Ramakrishnan, Wijnand Helfrich, Philip H. Elsinga, Anna A. Rybczynska, Aren van Waarde, Marco de Bruyn
Publikováno v:
Journal of Nuclear Medicine, 54(9), 1613-1620. SOC NUCLEAR MEDICINE INC
sigma-ligands can kill tumor cells. Previously we have shown that a short in vitro incubation of C6 tumor cells with sigma-ligands (24 h) results in a dose-dependent increase of cellular F-18-FDG uptake and that the magnitude of this increase is pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7843e130f32156a45da9f3b2fce2b5
https://doi.org/10.2967/jnumed.113.122655
https://doi.org/10.2967/jnumed.113.122655
Autor:
Jan Pruim, Rudi Dierckx, Anna A. Rybczynska, Jurgen W. A. Sijbesma, Chantal Kwizera, Krisztina Marosi, Philip H. Elsinga, Csaba Nyakas, Aren van Waarde, Anniek K. D. Visser, Kiichi Ishiwata, Nisha Kuzhuppilly Ramakrishnan
Publikováno v:
Journal of Nuclear Medicine, 54(8), 1377-1383. SOC NUCLEAR MEDICINE INC
Pituitary tumors are often detected only after death or at late stages of the disease when they are macroadenomas with a low surgical cure rate. Spontaneous pituitary tumors occur in rats over 1 y of age. In an ongoing study of changes in sigma-1 ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5606a3bac8c51f8c2d6333fd0c2c88
https://doi.org/10.2967/jnumed.112.115931
https://doi.org/10.2967/jnumed.112.115931