Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Anna Stamp"'
Autor:
Amanda J Cork, Daniel J Ericsson, Ruby H P Law, Lachlan W Casey, Eugene Valkov, Carlo Bertozzi, Anna Stamp, Blagojce Jovcevski, J Andrew Aquilina, James C Whisstock, Mark J Walker, Bostjan Kobe
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121764 (2015)
Group A Streptococcus (GAS) is a human pathogen that has the potential to cause invasive disease by binding and activating human plasmin(ogen). Streptococcal surface enolase (SEN) is an octameric α-enolase that is localized at the GAS cell surface.
Externí odkaz:
https://doaj.org/article/03fc1f9b0db34e69a31d06cf62fa17fd
Autor:
Carl A Morrow, Eugene Valkov, Anna Stamp, Eve W L Chow, I Russel Lee, Ania Wronski, Simon J Williams, Justine M Hill, Julianne T Djordjevic, Ulrike Kappler, Bostjan Kobe, James A Fraser
Publikováno v:
PLoS Pathogens, Vol 8, Iss 10, p e1002957 (2012)
We have investigated the potential of the GTP synthesis pathways as chemotherapeutic targets in the human pathogen Cryptococcus neoformans, a common cause of fatal fungal meningoencephalitis. We find that de novo GTP biosynthesis, but not the alterna
Externí odkaz:
https://doaj.org/article/33cc5f6ca2e241689d79d1cbab96ad8a
Publikováno v:
Resources, Conservation and Recycling. 93:156-167
Some renewable energy technologies rely on the functionalities provided by geochemically scarce metals. One example are CIGS solar cells, an emerging thin film photovoltaic technology, which contain indium. In this study we model global future indium
Publikováno v:
Resources, Conservation and Recycling. 80:85-96
Integrated smelter-refineries play an important role in the recovery of multiple metals from complex primary and secondary materials, and hence in closing metals cycles. Processes in these facilities are strongly interconnected, dynamic, and multifun
Publikováno v:
Science of The Total Environment. :785-791
Minerals and metals are finite resources, and recent evidence suggests that for many, primary production is becoming more difficult and more expensive. Yet these resources are fundamentally important for society—they support many critical services
Autor:
Eugene Valkov, Anna Stamp, Frank DiMaio, David Baker, Brett Verstak, Pietro Roversi, Stuart Kellie, Matthew J. Sweet, Ashley Mansell, Nicholas J. Gay, Jennifer L. Martin, Bostjan Kobe
Publikováno v:
Proceedings of the National Academy of Sciences. 108:14879-14884
Initiation of the innate immune response requires agonist recognition by pathogen-recognition receptors such as the Toll-like receptors (TLRs). Toll/interleukin-1 receptor (TIR) domain-containing adaptors are critical in orchestrating the signal tran
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 66:1104-1107
Fungal human pathogens such asCryptococcus neoformansare becoming an increasingly prevalent cause of human morbidity and mortality owing to the increasing numbers of susceptible individuals. The few antimycotics available to combat these pathogens us
Autor:
Rainer Zah, Hans-Jörg Althaus, Anna Stamp, Rolf Widmer, Dominic A. Notter, Patrick Wäger, Marcel Gauch
Publikováno v:
Environmental Science & Technology. 44:6550-6556
Battery-powered electric cars (BEVs) play a key role in future mobility scenarios. However, little is known about the environmental impacts of the production, use and disposal of the lithium ion (Li-ion) battery. This makes it difficult to compare th
Autor:
A.R. Hawkins, David K. Stammers, Heather K. Lamb, C.E. Nichols, Michael Lockyer, Ian G. Charles, Paul J. Owen, Anna Stamp, Kamel El Omari
Publikováno v:
Protein Science. 19:1897-1905
YcbL has been annotated as either a metallo-β-lactamase or glyoxalase II (GLX2), both members of the zinc metallohydrolase superfamily, that contains many enzymes with a diverse range of activities. Here, we report crystallographic and biochemical d
Autor:
Kurt Weaver, Jingshan Ren, L R Boone, R G Ferris, A Freeman, Steven A. Short, Anna Stamp, Richard J. Hazen, K.R Romines, C W Andrews Iii, P.P. Chamberlain, David K. Stammers, Joseph H. Chan
Publikováno v:
Journal of Medicinal Chemistry. 51:5000-5008
Owing to the emergence of resistant virus, next generation non-nucleoside HIV reverse transcriptase inhibitors (NNRTIs) with improved drug resistance profiles have been developed to treat HIV infection. Crystal structures of HIV-1 RT complexed with b