Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Anna Radominska-Pandya"'
Autor:
Sabrina Jones, Azure L. Yarbrough, William E. Fantegrossi, Paul L. Prather, John M. Bush, Anna Radominska‐Pandya, Ryoichi Fujiwara
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 1, Pp n/a-n/a (2020)
Abstract Synthetic cannabinoids (SCBs), designer drugs marketed as legal alternatives to marijuana, act as ligands to cannabinoid receptors; however, they have increased binding affinity and potency, resulting in toxicity symptoms such as cardiovascu
Externí odkaz:
https://doaj.org/article/2add3f1723ec473490047abd6c28cb76
Autor:
Anna O. Pinson, Dakota L. Pouncey, Mary A. Schleiff, William E. Fantegrossi, Paul L. Prather, Anna Radominska-Pandya, Gunnar Boysen, Grover P. Miller
Publikováno v:
Molecules, Vol 25, Iss 20, p 4820 (2020)
In 2020, nearly one-third of new drugs on the global market were synthetic cannabinoids including the drug of abuse N-(1-adamantyl)-1-(5-pentyl)-1H-indazole-3-carboxamide (5F-APINACA, 5F-AKB48). Knowledge of 5F-APINACA metabolism provides a critical
Externí odkaz:
https://doaj.org/article/5feebe5b535f47bcb7057517bd1b8506
Autor:
Rachel D. Hutchison, Benjamin M. Ford, Lirit N. Franks, Catheryn D. Wilson, Azure L. Yarbrough, Ryoichi Fujiwara, Mark K. Su, Denise Fernandez, Laura P. James, Jeffery H. Moran, Amy L. Patton, William E. Fantegrossi, Anna Radominska-Pandya, Paul L. Prather
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Recreational use of marijuana is associated with few adverse effects, but abuse of synthetic cannabinoids (SCBs) can result in anxiety, psychosis, chest pain, seizures and death. To potentially explain higher toxicity associated with SCB use, we hypo
Externí odkaz:
https://doaj.org/article/358cfb9af72f41bd853d85b2af68a559
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167240 (2016)
Tamoxifen (Tam) is a selective estrogen receptor (ER) modulator (SERM) that is an essential drug to treat ER-positive breast cancer. Aside from known actions at ERs, recent studies have suggested that some SERMs like Tam also exhibit novel activity a
Externí odkaz:
https://doaj.org/article/dfc0fbd2ab6c402ba246907cb2ad18b1
Autor:
Joanna M. Little, Mika Kurkela, Julia Sonka, Sirkku Jäntti, Raimo Ketola, Stacie Bratton, Moshe Finel, Anna Radominska-Pandya
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 9, Pp 1694-1703 (2004)
Arachidonic acid (AA) can be metabolized to various metabolites, which can act as mediators of cellular processes. The objective of this work was to identify whether AA, prostaglandin (PG) B1 and E2, and 15- and 20-hydroxyeicosatetraenoic acids (15-
Externí odkaz:
https://doaj.org/article/5c9e886cdafb4e4088f609e2f22ae357
Autor:
Amal Shoeib, Anna Radominska-Pandya, Azure L. Yarbrough, Paul L. Prather, Lirit N. Franks, Karol Kacprzak, Alicja Urbaniak, Lori L. Hensley, Benjamin M. Ford
Publikováno v:
The FASEB Journal. 35
Autor:
Dakota L. Pouncey, Anna Radominska-Pandya, Anna O. Pinson, Grover P. Miller, Gunnar Boysen, Mary A. Schleiff, Paul L. Prather, William E. Fantegrossi
Publikováno v:
Molecules
Molecules, Vol 25, Iss 4820, p 4820 (2020)
Volume 25
Issue 20
Molecules, Vol 25, Iss 4820, p 4820 (2020)
Volume 25
Issue 20
In 2020, nearly one-third of new drugs on the global market were synthetic cannabinoids including the drug of abuse N-(1-adamantyl)-1-(5-pentyl)-1H-indazole-3-carboxamide (5F-APINACA, 5F-AKB48). Knowledge of 5F-APINACA metabolism provides a critical
Autor:
John Bush, Ryoichi Fujiwara, Azure L. Yarbrough, William E. Fantegrossi, Anna Radominska-Pandya, Paul L. Prather, Sabrina Jones
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 1, Pp n/a-n/a (2020)
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives
Synthetic cannabinoids (SCBs), designer drugs marketed as legal alternatives to marijuana, act as ligands to cannabinoid receptors; however, they have increased binding affinity and potency, resulting in toxicity symptoms such as cardiovascular incid
Autor:
Amy L. Patton, Laura P. James, William E. Fantegrossi, Keith R. McCain, Jeffery H. Moran, Anna Radominska-Pandya, Paul L. Prather, Ryoichi Fujiwara, Azure L. Yarbrough, Kathryn A. Seely
Publikováno v:
Biochemical and Biophysical Research Communications. 498:597-602
Synthetic cannabinoids (SCBs), synonymous with ‘K2’, ‘Spice’ or ‘synthetic marijuana’, are psychoactive drugs of abuse that frequently result in clinical effects and toxicity more severe than those classically associated with Δ9-tetrahyd
Autor:
Lance N. Benson, Amal Shoeib, Anna Radominska-Pandya, Lirit N. Franks, Shengyu Mu, Paul L. Prather, Azure L. Yarbrough, Alicja Urbaniak, Lori L. Hensley, Benjamin M. Ford
Publikováno v:
Life Sciences. 285:119993
Aims Characterizing cannabinoid receptors (CBRs) expressed in Ewing sarcoma (EWS) cell lines as potential targets for anti-cancer drug development. Main methods CBR affinity and function were examined by competitive binding and G-protein activation,