p53 is associated with high‐risk and pinpoints TP53 missense mutations in mantle cell lymphoma

Autor: Christian Winther Eskelund, May Hassan, Mats Jerkeman, Anna Porwit, Anna Kwiecinska, Riikka Räty, Joana M. Rodrigues, Arne Kolstad, Christian H. Geisler, Sara Ek, Kirsten Grønbæk, Ingrid Glimelius, Catja Freiburghaus, Christer Sundström

Publikováno v: British Journal of Haematology
Rodrigues, J M, Hassan, M, Freiburghaus, C, Eskelund, C W, Geisler, C, Räty, R, Kolstad, A, Sundström, C, Glimelius, I, Grønbæk, K, Kwiecinska, A, Porwit, A, Jerkeman, M & Ek, S 2020, ' p53 is associated with high-risk and pinpoints TP53 missense mutations in mantle cell lymphoma ', British Journal of Haematology, vol. 191, no. 5, pp. 796-805 . https://doi.org/10.1111/bjh.17023

Survival for patients diagnosed with mantle cell lymphoma (MCL) has improved drastically in recent years. However, patients carrying mutations in tumour protein p53 (TP53) do not benefit from modern chemotherapy-based treatments and have poor prognos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57015c8694d34a71e33cee7ee740a0f0
http://europepmc.org/articles/PMC7754513

HAX ‐1 overexpression in multiple myeloma is associated with poor survival

Autor: Anna Porwit, Bengt Fadeel, Xiaoli Feng, Eva Rossmann, Manuel Patarroyo, Anders Österborg, Taichi Ishikawa, Anna Kwiecinska, Matteo Bottai, Chengyun Zheng

Publikováno v: British Journal of Haematology. 185:179-183

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a2ee0262a273d92640955bd2ecb0f3
https://doi.org/10.1111/bjh.15430

Proteomic Profiling of Diffuse Large B-Cell Lymphomas

Autor: Ann Kaufeldt, Svetlana Bajalica-Lagercrantz, Serhiy Souchelnytskyi, Catharina Larsson, Nazariy Souchelnytskyi, Anna Kwiecinska, Anna Porwit

Publikováno v: Pathobiology : journal of immunopathology, molecular and cellular biology. 85(4)

Objective: The aim of this study was to identify differences in proteome profiles of diffuse large B-cell lymphoma (DLBCL) of nongerminal center (non-GC) versus GC type in the search for new markers and drug targets. Methods: Six DLBCL, with 3 repeat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7af0f9c08e0b01a652000c7366cb36
https://pubmed.ncbi.nlm.nih.gov/29617697

Patients with activated B-cell like diffuse large B-cell lymphoma in high and low infectious disease areas have different inflammatory gene signatures

Autor: Abdel-Rahman N. Zekri, Therese Högfeldt, Joachim Lundahl, Katja Pokrovskaja Tamm, Abeer A. Bahnassy, Ali Moshfegh, Håkan Mellstedt, Anders Österborg, Hussein M. Khaled, Anna Porwit, Anna Kwiecinska

Publikováno v: Leukemia & Lymphoma. 54:996-1003

Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with an association with inflammation and viral infections. We hypothesize that environmental factors may be involved in the pathogenesis of DLBCL. In this study, we compared gene expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48208c185d24e2cbb655a0ab186933df
https://doi.org/10.3109/10428194.2012.738365

Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells

Autor: Magnus Bäcklund, Cătălina Gabriela Pisoschi, Vasile Ciubotaru, Anica Dricu, Monica Banita, Oana Alexandru, Raluca Budiu, Rolf Lewensohn, Mia Carapancea, Daria Cosaceanu, Ligia Gabriela Tataranu, Anna Kwiecinska

Publikováno v: Journal of Neuro-Oncology. 85:245-254

Increased expression and activation of receptor tyrosine kinases frequently occur in human brain tumors, mediating a variety of growth-promoting pathways and leading to radioresistance; however, little is known about their motogenic potency relative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b971e431f19cea1fc76bde5583591fd
https://doi.org/10.1007/s11060-007-9417-0