Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anna Halámiková"'
Autor:
Lenka Zerzankova, Viktor Brabec, Oldrich Vrana, Jana Kasparkova, Nicola Margiotta, Tereza Suchankova, Anna Halámiková, Giovanni Natile
Publikováno v:
Biochemical Pharmacology. 79:552-564
Earlier studies have described promising antitumor activity of a large-ring chelate complex [PtCl(2)(cis-1,4-DACH)] (DACH=diaminocyclohexane). Encouraging antitumor activity of this analogue of cisplatin prompted us to perform studies focused on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a90b9835e6cc2ac381d01c71294d73a
https://doi.org/10.1016/j.bcp.2009.09.019
https://doi.org/10.1016/j.bcp.2009.09.019
Autor:
Jana Kasparkova, Viktor Brabec, Simon Parsons, Lenka Zerzankova, Tijana Bugarcic, Oldřich Vrána, Peter J. Sadler, Olga Novakova, Anna Halámiková, Abraha Habtemariam
Publikováno v:
Journal of Medicinal Chemistry. 51:5310-5319
We have compared the cancer cell cytotoxicity, cell uptake, and DNA binding properties of the isomeric terphenyl complexes [(eta(6)-arene)Ru(en)Cl](+), where the arene is ortho- (2), meta- (3), or para-terphenyl (1) (o-, m-, or p-terp). Complex 1, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993f30a6ab847366467f2436010e4720
https://doi.org/10.1021/jm8003043
https://doi.org/10.1021/jm8003043
Autor:
Jana Kasparkova, Dan Gibson, Viktor Brabec, Francesco P. Intini, Pavla Heringova, Alina Nemirovski, Giovanni Natile, Anna Halámiková
Publikováno v:
Journal of Inorganic Biochemistry. 102:1077-1089
Cytotoxicity and mutagenicity of trans,trans,trans-[PtCl2(CH3COO)2(NH3)(1-adamantylamine)] [trans-adamplatin(IV)] and its reduced analog trans-[PtCl2(NH3)(1-adamantylamine)] [trans-adamplatin(II)] were examined. In addition, the several factors under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48a31d1508d991e4ff4c2c53d0598b5
https://doi.org/10.1016/j.jinorgbio.2007.12.015
https://doi.org/10.1016/j.jinorgbio.2007.12.015
Publikováno v:
ChemBioChem. 8:2008-2015
Using biochemical methods, we have examined the effect of two factors that might play a role in the mechanism of the biological activity of cisplatin at elevated temperatures (>37 degrees C). We show that increased temperatures result in distinct alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238599f69c913ca7b355a5c30b98ea1a
https://doi.org/10.1002/cbic.200700288
https://doi.org/10.1002/cbic.200700288
Autor:
Anna Halámiková, Giovanni Natile, Viktor Brabec, Vladan Bernard, Jaroslav Malina, Jana Kasparkova, Olga Novakova, Francesco P. Intini
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 15(25)
In early studies of empirical structure-activity relationships, monodentate Pt(II) complexes were considered to be biologically inactive. Examples of such inactive monodentate Pt(II) compounds are [PtCl(dien)]+ (dien=diethylenetriamine) and [PtCl(NH3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6a113c185ea0581b6cab70c61fcafc
https://pubmed.ncbi.nlm.nih.gov/19449361
https://pubmed.ncbi.nlm.nih.gov/19449361
Autor:
Viktor Brabec, Anna Halámiková, Oldrich Vrana, Hana Rybnícková, Carmen Navarro-Ranninger, Adoración G. Quiroga, Francisco J. Ramos-Lima, Lenka Hejmalová
Publikováno v:
Journal of medicinal chemistry. 49(8)
We report in the present work new analogues of clinically ineffective transplatin in which one ammine group was replaced by aliphatic and the other by a planar heterocyclic ligand, namely trans-[PtCl(2)(isopropylamine)(3-(hydroxymethyl)-pyridine)], 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f990e19ee27bf8a8b226659c35d4f665
https://pubmed.ncbi.nlm.nih.gov/16610807
https://pubmed.ncbi.nlm.nih.gov/16610807
Autor:
Tijana Bugarcic, Olga Nováková, Anna Halámiková, Lenka Zerzánková, Oldřich Vrána, Jana Kašpárková, Abraha Habtemariam, Simon Parsons, Peter J. Sadler, Viktor Brabec
Publikováno v:
Journal of Medicinal Chemistry; Jul2008, Vol. 51 Issue 17, p5310-5319, 10p