Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Anna Ellsworth"'
Autor:
Mauro Montalbano, Elizabeth Jaworski, Stephanie Garcia, Anna Ellsworth, Salome McAllen, Andrew Routh, Rakez Kayed
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Tau protein is a known contributor in several neurodegenerative diseases, including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). It is well-established that tau forms pathological aggregates and fibrils in these diseases. Tau has bee
Externí odkaz:
https://doaj.org/article/e82630aa9dc645a094f19b3dcebd97b6
Autor:
Mauro Montalbano, Salome McAllen, Filippa Lo Cascio, Urmi Sengupta, Stephanie Garcia, Nemil Bhatt, Anna Ellsworth, Eric A. Heidelman, Omar D. Johnson, Samantha Doskocil, Rakez Kayed
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105130- (2020)
Proteinaceous aggregates are major hallmarks of several neurodegenerative diseases. Aggregates of post-translationally modified transactive response (TAR)-DNA binding protein 43 (TDP-43) in cytoplasmic inclusion bodies are characteristic features in
Externí odkaz:
https://doaj.org/article/d9510ba996114ef685a27d88a84a1bf5
Autor:
Alice Bittar, Rabab Al-Lahham, Nemil Bhatt, Kenya Moore, Mauro Montalbano, Cynthia Jerez, Leiana Fung, Salome McAllen, Anna Ellsworth, Rakez Kayed
Publikováno v:
Journal of Alzheimer's Disease. 90:1103-1122
Background: Tau oligomers are one of the most toxic species, displaying prion-like strains which have different conformations resulting in different tauopathies. Passive immunotherapy targeting different tau species is a promising therapeutic approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b48476c529581443aed134e1f97643
https://doi.org/10.3233/jad-220518
https://doi.org/10.3233/jad-220518
Autor:
Thomas M Schindler, Frank Grieger, Anna Zak, Ramona Rorig, Kavya Chowdary Konka, Anna Ellsworth, Christopher Pfitzer, Keir Hodge, Christine Crandall, TransCelerate Clinical Research Access & Information Exchange Initiative
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233294 (2020)
ClinicalTrials.gov was started with the intention to create a consumer-friendly database for patients and others in search of information on clinical trials. However, there is no research on whether the content of ClinicalTrials.gov aligns with patie
Externí odkaz:
https://doaj.org/article/dcd4cb3c65294a0188d39274f149fb15
Autor:
Mauro Montalbano, Elizabeth Jaworski, Stephanie Garcia, Anna Ellsworth, Salome McAllen, Andrew Routh, Rakez Kayed
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bda37a2dae63f6ce3e6ada023dc808f4
https://doi.org/10.1096/fasebj.2022.36.s1.0r784
https://doi.org/10.1096/fasebj.2022.36.s1.0r784
Autor:
Rakez Kayed, Urmi Sengupta, Filippa Lo Cascio, Stephanie Garcia, Anna Ellsworth, Salome McAllen, Mauro Montalbano, Nemil Bhatt, Omar D. Johnson, Samantha Doskocil, Eric A. Heidelman
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 146, Iss, Pp 105130-(2020)
Neurobiology of Disease, Vol 146, Iss, Pp 105130-(2020)
Proteinaceous aggregates are major hallmarks of several neurodegenerative diseases. Aggregates of post-translationally modified transactive response (TAR)-DNA binding protein 43 (TDP-43) in cytoplasmic inclusion bodies are characteristic features in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b236ae676a36c1a531fe5c4a833230f
https://pubmed.ncbi.nlm.nih.gov/33065281
https://pubmed.ncbi.nlm.nih.gov/33065281
Autor:
Rakez Kayed, Urmi Sengupta, Nemil Bhatt, Marcos J. Guerrero-Muñoz, Daniel V. Cantu, Gaurav Ghag, Anna Ellsworth
Publikováno v:
Protein Science. 27:1901-1909
Several studies have proposed that fibrillary aggregates of tau and other amyloidogenic proteins are neurotoxic and result in numerous neurodegenerative diseases. However, these studies usually involve sonication or extrusion through needles before e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eadaacf53a740e442a96895ab61de68
https://doi.org/10.1002/pro.3499
https://doi.org/10.1002/pro.3499
Autor:
Salome McAllen, Stephanie Garcia, Anna Ellsworth, Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Sagar Gaikwad, Mauro Montalbano, Rakez Kayed, Frank Ventura
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 5, Pp 1-16 (2020)
Cell Death and Disease, Vol 11, Iss 5, Pp 1-16 (2020)
Tau aggregates propagate in brain cells and transmit to neighboring cells as well as anatomically connected brain regions by prion-like mechanisms. Soluble tau aggregates (tau oligomers) are the most toxic species that initiate neurodegeneration in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dc854897829c763655f945dfb7ea46
https://pubmed.ncbi.nlm.nih.gov/32366836
https://pubmed.ncbi.nlm.nih.gov/32366836
Autor:
Nicha Puangmalai, Filippa Lo Cascio, Anna Ellsworth, Fabio Bucchieri, Rakez Kayed, Antonio Palumbo Piccionello, Andrea Pace
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
Scientific Reports
The pathological aggregation and accumulation of tau, a microtubule-associated protein, is a common feature amongst more than 18 different neurodegenerative diseases that are collectively known as tauopathies. Recently, it has been demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdb9148135b6b2c9ae02b5628e92bf9
http://hdl.handle.net/10447/389547
http://hdl.handle.net/10447/389547
Autor:
Mauro Montalbano, Rakez Kayed, Charles L. Rosen, Brandon Lucke-Wold, Tasneem F. Hasan, Nicha Puangmalai, Alice Bittar, Giulio Taglialatela, Mariana Carretero Murillo, Nemil Bhatt, Ryan C. Turner, Salome McAllen, Aric F. Logsdon, Anna Ellsworth
Publikováno v:
Brain Communications
Soluble tau aggregates have been highlighted in mTBI-induced cellular dysfunction and neurodegeneration. We used an established mTBI model to investigate differences between tau oligomers isolated after single vs. repetitive mTBI. Single and repeated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80a33631077111f0b7044fe8f42f292
http://europepmc.org/articles/PMC6777515
http://europepmc.org/articles/PMC6777515