Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anna‐Lisa Schaap‐Johansen"'
Autor:
Annie Borch, Ibel Carri, Birkir Reynisson, Heli M. Garcia Alvarez, Kamilla K. Munk, Alessandro Montemurro, Nikolaj Pagh Kristensen, Siri A. Tvingsholm, Jeppe Sejerø Holm, Christina Heeke, Keith Henry Moss, Ulla Kring Hansen, Anna-Lisa Schaap-Johansen, Frederik Otzen Bagger, Vinicius Araujo Barbosa de Lima, Kristoffer S. Rohrberg, Samuel A. Funt, Marco Donia, Inge Marie Svane, Ulrik Lassen, Carolina Barra, Morten Nielsen, Sine Reker Hadrup
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMutation-derived neoantigens are critical targets for tumor rejection in cancer immunotherapy, and better tools for neoepitope identification and prediction are needed to improve neoepitope targeting strategies. Computational tools have ena
Externí odkaz:
https://doaj.org/article/0bbbca7628154c30a577b6a43214db8d
Autor:
Milena Vujovic, Kristine Fredlund Degn, Frederikke Isa Marin, Anna-Lisa Schaap-Johansen, Benny Chain, Thomas Lars Andresen, Joseph Kaplinsky, Paolo Marcatili
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 2166-2173 (2020)
There has been increasing interest in the role of T cells and their involvement in cancer, autoimmune and infectious diseases. However, the nature of T cell receptor (TCR) epitope recognition at a repertoire level is not yet fully understood. Due to
Externí odkaz:
https://doaj.org/article/2dfbf80f6953464c86c5c29087484c1e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T cells play a crucial role in controlling and driving the immune response with their ability to discriminate peptides derived from healthy as well as pathogenic proteins. In this review, we focus on the currently available computational tools for ep
Externí odkaz:
https://doaj.org/article/014c5709734849d88591d7722a5d9995
Publikováno v:
Computer-Aided Antibody Design ISBN: 9781071626085
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8dfce9288ac69f45750797263a8c45c
https://doi.org/10.1007/978-1-0716-2609-2_27
https://doi.org/10.1007/978-1-0716-2609-2_27
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2552
Mutant Peptide eXtractor and Informer (MuPeXI), by Bjerregaard et al. (Cancer Immunol Immunother CII 66:1123-1130, 2017), is a program which identifies tumor-specific peptides and assesses their potential to be neoepitopes. MuPeXI takes as input a VC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df5af4012ff67c873194f5b62df00cf3
https://pubmed.ncbi.nlm.nih.gov/36346610
https://pubmed.ncbi.nlm.nih.gov/36346610
Autor:
Paolo Marcatili, Kristine Fredlund Degn, Milena Vujović, Thomas Lars Andresen, Frederikke Isa Marin, Anna-Lisa Schaap-Johansen, Joseph Kaplinsky, Benny Chain
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2166-2173 (2020)
Computational and Structural Biotechnology Journal
Vujovic, M, Degn, K F, Marin, F I, Schaap-Johansen, A-L, Chain, B, Andresen, T L, Kaplinsky, J & Marcatili, P 2020, ' T cell receptor sequence clustering and antigen specificity ', Computational and Structural Biotechnology Journal, vol. 18, pp. 2166-2173 . https://doi.org/10.1016/j.csbj.2020.06.041
Computational and Structural Biotechnology Journal
Vujovic, M, Degn, K F, Marin, F I, Schaap-Johansen, A-L, Chain, B, Andresen, T L, Kaplinsky, J & Marcatili, P 2020, ' T cell receptor sequence clustering and antigen specificity ', Computational and Structural Biotechnology Journal, vol. 18, pp. 2166-2173 . https://doi.org/10.1016/j.csbj.2020.06.041
There has been increasing interest in the role of T cells and their involvement in cancer, autoimmune and infectious diseases. However, the nature of T cell receptor (TCR) epitope recognition at a repertoire level is not yet fully understood. Due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429fba6100b387521ee527f0b9cd6ebd
http://www.sciencedirect.com/science/article/pii/S2001037020303305
http://www.sciencedirect.com/science/article/pii/S2001037020303305
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Schaap-Johansen, A L, Vujović, M, Borch, A, Hadrup, S R & Marcatili, P 2021, ' T Cell Epitope Prediction and Its Application to Immunotherapy ', Frontiers in Immunology, vol. 12, 712488 . https://doi.org/10.3389/fimmu.2021.712488
Frontiers in Immunology, Vol 12 (2021)
Schaap-Johansen, A L, Vujović, M, Borch, A, Hadrup, S R & Marcatili, P 2021, ' T Cell Epitope Prediction and Its Application to Immunotherapy ', Frontiers in Immunology, vol. 12, 712488 . https://doi.org/10.3389/fimmu.2021.712488
T cells play a crucial role in controlling and driving the immune response with their ability to discriminate peptides derived from healthy as well as pathogenic proteins. In this review, we focus on the currently available computational tools for ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa862b4ca3f7fe9981df019b923f272
http://europepmc.org/articles/PMC8479193
http://europepmc.org/articles/PMC8479193
Autor:
Paolo Marcatili, Maria Karipidou, Sofia Gkagkaridou, Niki Stavroyianni, Anastasia Chatzidimitriou, Kostas Stamatopoulos, Achilles Anagnostopoulos, Asimina Fylaktou, Anna Vardi, A. Agathangelidis, Sine Reker Hadrup, Anna-Lisa Schaap-Johansen, Michail Iskas, Anna Boukla
Publikováno v:
Blood. 138:1540-1540
Targeted therapies have revolutionized the treatment of chronic lymphocytic leukemia (CLL) with remarkable overall response rates. Against that, however, CLL remains incurable, indicating a need for novel strategies towards disease control and eventu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac697a5c72e4746d1f7f42a0afe0add0
https://doi.org/10.1182/blood-2021-152422
https://doi.org/10.1182/blood-2021-152422
Autor:
Julio Vacacela, Anna‐Lisa Schaap‐Johansen, Patricia Manikova, Paolo Marcatili, Marta Prado, Yi Sun, Jon Ashley
Publikováno v:
Vacacela, J, Schaap-Johansen, A-L, Manikova, P, Marcatili, P, Prado, M, Sun, Y & Ashley, J 2022, ' The Protein-Templated Synthesis of Enzyme-Generated Aptamers ', ANGEWANDTE CHEMIE, vol. 61, e20220106 . https://doi.org/10.1002/anie.202201061
Inspired by the chemical synthesis of molecularly imprinted polymers, we demonstrated for the first time, the protein-target mediated synthesis of enzyme-generated aptamers (EGAs). We prepared pre-polymerisation mixtures containing different ratios o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7387547bf7c86af963af4de653256572
Autor:
Jon Ashley, Paolo Marcatili, Anna-Lisa Schaap-Johansen, Marta Prado, Mohsen Mohammadniaei, Maryam Naseri, Yi Sun
Publikováno v:
Nucleic Acids Research
Ashley, J, Schaap-Johansen, A-L, Mohammadniaei, M, Naseri, M, Marcatili, P, Prado, M & Sun, Y 2021, ' Terminal deoxynucleotidyl transferase-mediated formation of protein binding polynucleotides ', Nucleic Acids Research, vol. 49, no. 2, pp. 1065–1074 . https://doi.org/10.1093/nar/gkaa1263
Ashley, J, Schaap-Johansen, A-L, Mohammadniaei, M, Naseri, M, Marcatili, P, Prado, M & Sun, Y 2021, ' Terminal deoxynucleotidyl transferase-mediated formation of protein binding polynucleotides ', Nucleic Acids Research, vol. 49, no. 2, pp. 1065–1074 . https://doi.org/10.1093/nar/gkaa1263
Terminal deoxynucleotidyl transferase (TdT) enzyme plays an integral part in the V(D)J recombination, allowing for the huge diversity in expression of immunoglobulins and T-cell receptors within lymphocytes, through their unique ability to incorporat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becd9203792c27f53ccf129f6c218c5e