Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Anna‐Lena Spetz"'
Autor:
Kahkashan Kamal, Elina Richardsdotter‐Andersson, Aleksandra Dondalska, Marie Wahren‐Herlenius, Anna‐Lena Spetz
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Skin‐resident antigen‐presenting cells (APC) play an important role in maintaining peripheral tolerance via immune checkpoint proteins and induction of T regulatory cells (Tregs). However, there is a lack of knowledge on how to expand or
Externí odkaz:
https://doaj.org/article/f29ca782dccb4219a66401f82208e211
Autor:
Rüdiger Groß, Lívia Mesquita Dias Loiola, Leila Issmail, Nadja Uhlig, Valentina Eberlein, Carina Conzelmann, Lia‐Raluca Olari, Lena Rauch, Jan Lawrenz, Tatjana Weil, Janis A. Müller, Mateus Borba Cardoso, Andrea Gilg, Olivia Larsson, Urban Höglund, Sandra Axberg Pålsson, Anna Selch Tvilum, Kaja Borup Løvschall, Maria M. Kristensen, Anna‐Lena Spetz, Fortune Hontonnou, Marie Galloux, Thomas Grunwald, Alexander N. Zelikin, Jan Münch
Publikováno v:
Advanced Science, Vol 9, Iss 20, Pp n/a-n/a (2022)
Abstract Inhibitors of viral cell entry based on poly(styrene sulfonate) and its core–shell nanoformulations based on gold nanoparticles are investigated against a panel of viruses, including clinical isolates of SARS‐CoV‐2. Macromolecular inhi
Externí odkaz:
https://doaj.org/article/efb36e92da2449a5bac3fba657c93ca6
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14593 (2022)
Here, we link approved and emerging nucleic acid-based therapies with the expanding universe of small non-coding RNAs (sncRNAs) and the innate immune responses that sense oligonucleotides taken up into endosomes. The Toll-like receptors (TLRs) 3, 7,
Externí odkaz:
https://doaj.org/article/4029bf7f42d54fdf8d029b074091b982
Autor:
Kariem Ezzat, Maria Pernemalm, Sandra Pålsson, Thomas C. Roberts, Peter Järver, Aleksandra Dondalska, Burcu Bestas, Michal J. Sobkowiak, Bettina Levänen, Magnus Sköld, Elizabeth A. Thompson, Osama Saher, Otto K. Kari, Tatu Lajunen, Eva Sverremark Ekström, Caroline Nilsson, Yevheniia Ishchenko, Tarja Malm, Matthew J. A. Wood, Ultan F. Power, Sergej Masich, Anders Lindén, Johan K. Sandberg, Janne Lehtiö, Anna-Lena Spetz, Samir EL Andaloussi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The protein corona around artificial nanoparticles is known to influence activity and biological fate, the formation around viruses is less well understood. Here, the authors observe the formation of protein corona on viruses and study the effects th
Externí odkaz:
https://doaj.org/article/707b1edf615a4fe08fe6eacaded85b36
Autor:
Amparo Martínez-Pérez, Ana Igea, Olivia Estévez, Catarina M. Ferreira, Egídio Torrado, António Gil Castro, Carmen Fernández, Anna-Lena Spetz, Lucille Adam, Moisés López González, Mahavir Singh, Rajko Reljic, África González-Fernández
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Deciphering protection mechanisms against Mycobacterium tuberculosis (Mtb) remains a critical challenge for the development of new vaccines and therapies. We analyze the phenotypic and transcriptomic profile in lung of a novel tuberculosis (TB) nanop
Externí odkaz:
https://doaj.org/article/e3193b8600fc43afa04f6076f210103e
Autor:
Sandra Axberg Pålsson, Aleksandra Dondalska, Joseph Bergenstråhle, Caroline Rolfes, Albin Björk, Laura Sedano, Ultan F. Power, Marie-Anne Rameix-Welti, Joakim Lundeberg, Marie Wahren-Herlenius, Peter Mastrangelo, Jean-Francois Eleouet, Ronan Le Goffic, Marie Galloux, Anna-Lena Spetz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory tract infections in young children. Currently, there is no RSV vaccine or universally accessible antiviral treatment available. Addressing the urgent need for new antiv
Externí odkaz:
https://doaj.org/article/1928873cab324d6fa11999043dd621a5
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5990 (2022)
Respiratory syncytial virus (RSV) causes acute lower respiratory tract infection in infants, immunocompromised individuals and the elderly. As the only current specific treatment options for RSV are monoclonal antibodies, there is a need for efficaci
Externí odkaz:
https://doaj.org/article/92dd3cacc3014c07afc6ff48232d717c
Autor:
Aleksandra Dondalska, Elin Rönnberg, Haisha Ma, Sandra Axberg Pålsson, Elin Magnusdottir, Tianle Gao, Lucille Adam, Ethan A. Lerner, Gunnar Nilsson, Malin Lagerström, Anna-Lena Spetz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Numerous inflammatory skin disorders display a high prevalence of itch. The Mas-related G protein coupled receptor X2 (MRGPRX2) has been shown to modulate itch by inducing non-IgE-mediated mast cell degranulation and the release of endogenous inducer
Externí odkaz:
https://doaj.org/article/e7744e88d4984ca48b72f1c9cb4a62bb
Autor:
Peter Järver, Aleksandra Dondalska, Candice Poux, AnnSofi Sandberg, Joseph Bergenstråhle, Annette E. Sköld, Nathalie Dereuddre-Bosquet, Fréderic Martinon, Sandra Pålsson, Eman Zaghloul, David Brodin, Birgitta Sander, Kim A. Lennox, Mark A. Behlke, Samir EL-Andaloussi, Janne Lehtiö, Joakim Lundeberg, Roger LeGrand, Anna-Lena Spetz
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract Recognition of nucleic acids by endosomal Toll-like receptors (TLR) is essential to combat pathogens, but requires strict control to limit inflammatory responses. The mechanisms governing this tight regulation are unclear. We found that sing
Externí odkaz:
https://doaj.org/article/8ee60f6cd9e941b7b20a1654b77636dc
Autor:
Candice Poux, Aleksandra Dondalska, Joseph Bergenstråhle, Sandra Pålsson, Vanessa Contreras, Claudia Arasa, Peter Järver, Jan Albert, David C. Busse, Roger LeGrand, Joakim Lundeberg, John S. Tregoning, Anna-Lena Spetz
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The initiation of an immune response is dependent on the activation and maturation of dendritic cells after sensing pathogen associated molecular patterns by pattern recognition receptors. However, the response needs to be balanced as excessive pro-i
Externí odkaz:
https://doaj.org/article/15ac5559956a41ec8c1585cb51e3c25a