Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Anna‐Lena Heins"'
Autor:
Manh Dat Hoang, Ingmar Polte, Lukas Frantzmann, Nikolas von den Eichen, Anna-Lena Heins, Dirk Weuster-Botz
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-19 (2023)
Abstract Background The omnipresence of population heterogeneity in industrial bioprocesses originates from prevailing dynamic bioprocess conditions, which promote differences in the expression of cellular characteristics. Despite the awareness, the
Externí odkaz:
https://doaj.org/article/d8c47bc640c84cf5a83629758f9de8f2
Autor:
Manh Dat Hoang, Dieu Thi Doan, Marlen Schmidt, Harald Kranz, Andreas Kremling, Anna‐Lena Heins
Publikováno v:
Engineering in Life Sciences, Vol 23, Iss 1, Pp n/a-n/a (2023)
Abstract Biotechnological production processes are sustainable approaches for the production of biobased components such as amino acids for food and feed industry. Scale‐up from ideal lab‐scale bioreactors to large‐scale processes is often acco
Externí odkaz:
https://doaj.org/article/24e6696fad864c61b0cf5aad3175f460
Autor:
Manh Dat Hoang, Sophi Riessner, Jose Enrique Oropeza Vargas, Nikolas von den Eichen, Anna-Lena Heins
Publikováno v:
Microorganisms, Vol 11, Iss 7, p 1763 (2023)
When targeting robust, high-yielding bioprocesses, phenomena such as population heterogeneity have to be considered. Therefore, the influence of the conditions which the cells experience prior to the main culture should also be evaluated. Here, the i
Externí odkaz:
https://doaj.org/article/a80a71cb43f348b99e35dfc965962330
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Mathematical modeling is a promising tool for better understanding of cellular processes. In recent years, the development of coarse-grained models has gained attraction since these simple models are able to capture and describe a broad range of grow
Externí odkaz:
https://doaj.org/article/2497421247cc4bc391c63157c19eea49
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-20 (2020)
Abstract Background Today there is an increasing demand for high yielding robust and cost efficient biotechnological production processes. Although cells in these processes originate from isogenic cultures, heterogeneity induced by intrinsic and extr
Externí odkaz:
https://doaj.org/article/e56be849f982474383e1543620cfb34e
Autor:
Anna-Lena Heins, Ted Johanson, Shanshan Han, Luisa Lundin, Magnus Carlquist, Krist V. Gernaey, Søren J. Sørensen, Anna Eliasson Lantz
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Microbial cells in bioprocesses are usually described with averaged parameters. But in fact, single cells within populations vary greatly in characteristics such as stress resistance, especially in response to carbon source gradients. Our aim was to
Externí odkaz:
https://doaj.org/article/77623e11a0a746b8adf2c497d76d7a4a
Autor:
Prasika Arulrajah, Anna-Lena Heins
Publikováno v:
BIOspektrum. 29:241-244
Population heterogeneity poses a major challenge in industrial scale bioprocesses, affecting process performance but also leading to more robust phenotypes. To investigate this phenomenon, multiple fluorescent reporter strains are cultivated under si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::802b1c8b21b480126b31d5f9f5141ab6
https://doi.org/10.1007/s12268-023-1922-y
https://doi.org/10.1007/s12268-023-1922-y
Autor:
Manh Dat Hoang, Dieu Thi Doan, Marlen Schmidt, Harald Kranz, Andreas Kremling, Anna‐Lena Heins
Publikováno v:
Engineering in Life Sciences. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badca901844255e997efbe11a643df4f
https://doi.org/10.1002/elsc.202100162
https://doi.org/10.1002/elsc.202100162
Autor:
Manh Dat, Hoang, Dieu Thi, Doan, Marlen, Schmidt, Harald, Kranz, Andreas, Kremling, Anna-Lena, Heins
Publikováno v:
Engineering in life sciences. 23(1)
Biotechnological production processes are sustainable approaches for the production of biobased components such as amino acids for food and feed industry. Scale-up from ideal lab-scale bioreactors to large-scale processes is often accompanied by loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a520bfeec30a45eeb3c63c6fdf2b43e
https://pubmed.ncbi.nlm.nih.gov/36619877
https://pubmed.ncbi.nlm.nih.gov/36619877
Publikováno v:
Engineering in life sciences. 22(3-4)
Flow cytometry and its technological possibilities have greatly advanced in the past decade as analysis tool for single cell properties and population distributions of different cell types in bioreactors. Along the way, some solutions for automated r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2bbfa4774c89face563601a4f0ed86f1
https://pubmed.ncbi.nlm.nih.gov/35382548
https://pubmed.ncbi.nlm.nih.gov/35382548