Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Annaïk Quémard"'
Autor:
Shiva Kumar Angala, Ana Carreras-Gonzalez, Emilie Huc-Claustre, Itxaso Anso, Devinder Kaur, Victoria Jones, Zuzana Palčeková, Juan M. Belardinelli, Célia de Sousa-d’Auria, Libin Shi, Nawel Slama, Christine Houssin, Annaïk Quémard, Michael McNeil, Marcelo E. Guerin, Mary Jackson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract We report on the existence of two phosphatidic acid biosynthetic pathways in mycobacteria, a classical one wherein the acylation of the sn-1 position of glycerol-3-phosphate (G3P) precedes that of sn-2 and another wherein acylations proceed
Externí odkaz:
https://doaj.org/article/e654bf1aa0a4424ea44490ddc8479d50
Autor:
Cécile Bon, Stéphanie Cabantous, Sylviane Julien, Valérie Guillet, Christian Chalut, Julie Rima, Yoann Brison, Wladimir Malaga, Angelique Sanchez-Dafun, Sabine Gavalda, Annaïk Quémard, Julien Marcoux, Geoffrey S. Waldo, Christophe Guilhot, Lionel Mourey
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Type I polyketide synthases (PKSs) are multifunctional enzymes responsible for the biosynthesis of a group of diverse natural compounds with biotechnological and pharmaceutical interest called polyketides. The diversity of polyket
Externí odkaz:
https://doaj.org/article/ce957ac87b34489ba429e3036d0705f9
Autor:
Bernardo Bazet Lyonnet, Lautaro Diacovich, Matías Cabruja, Fabienne Bardou, Annaïk Quémard, Gabriela Gago, Hugo Gramajo
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242528 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0099853.].
Externí odkaz:
https://doaj.org/article/dc649760b61b48348c1a0da53ea505cf
Autor:
Bernardo Bazet Lyonnet, Lautaro Diacovich, Matías Cabruja, Fabienne Bardou, Annaïk Quémard, Gabriela Gago, Hugo Gramajo
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99853 (2014)
Mycobacteria contain a large variety of fatty acids which are used for the biosynthesis of several complex cell wall lipids that have been implicated in the ability of the organism to resist host defenses. The building blocks for the biosynthesis of
Externí odkaz:
https://doaj.org/article/fad22443856349268430e97b7cf34152
Autor:
Mamadou Daffé, Anne Lemassu, Patricia Constant, Wafa Frigui, Tanya Parish, Annaïk Quémard, Nathalie Eynard, Françoise Lauzeral-Vizcaino, Cyril Lefebvre, Nawel Slama, Roland Brosch
Publikováno v:
Scientific Reports
Scientific Reports, 2020, 10 (1), pp.2112. ⟨10.1038/s41598-020-58967-8⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.2112. ⟨10.1038/s41598-020-58967-8⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-58967-8⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, 2020, 10 (1), pp.2112. ⟨10.1038/s41598-020-58967-8⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.2112. ⟨10.1038/s41598-020-58967-8⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-58967-8⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
The fatty acid synthase type II (FAS-II) multienzyme system builds the main chain of mycolic acids (MAs), important lipid pathogenicity factors of Mycobacterium tuberculosis (Mtb). Due to their original structure, the identification of the (3 R)-hydr
Publikováno v:
Biogenesis of Fatty Acids, Lipids and Membranes
Biogenesis of Fatty Acids, Lipids and Membranes, Springer International Publishing, pp.181-216, 2019, ⟨10.1007/978-3-319-50430-8_18⟩
Biogenesis of Fatty Acids, Lipids and Membranes ISBN: 9783319436760
Biogenesis of Fatty Acids, Lipids and Membranes, Springer International Publishing, pp.181-216, 2019, ⟨10.1007/978-3-319-50430-8_18⟩
Biogenesis of Fatty Acids, Lipids and Membranes ISBN: 9783319436760
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed77e9f35e17bb9bf1c1c1cdcc8ffbfb
https://hal.archives-ouvertes.fr/hal-02388910
https://hal.archives-ouvertes.fr/hal-02388910
Autor:
Hugo Gramajo, Bernardo Bazet Lyonnet, Lautaro Diacovich, Matías Cabruja, Fabienne Bardou, Gabriela Gago, Annaïk Quémard
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0242528 (2020)
PLoS ONE, Vol 9, Iss 6, p e99853 (2014)
PLoS ONE, Vol 15, Iss 11, p e0242528 (2020)
PLoS ONE, Vol 9, Iss 6, p e99853 (2014)
Mycobacteria contain a large variety of fatty acids which are used for the biosynthesis of several complex cell wall lipids that have been implicated in the ability of the organism to resist host defenses. The building blocks for the biosynthesis of
Autor:
Annaïk Quémard
Publikováno v:
Trends in Microbiology. 24:725-738
Mycolic acids are extremely-long-chain fatty acids that compose a large family of mycolate-containing compounds, major envelope lipid components and critical pathogenicity factors of Mycobacterium tuberculosis. In recent years there have been major a
Autor:
Françoise Laval, Nawel Slama, Roland Brosch, Stevie Jamet, Anne Lemassu, Daria Bottai, Patricia Constant, Mamadou Daffé, Annaïk Quémard, Wafa Frigui, Nathalie Eynard, Alexandre Pawlik, Kaymeuang Cam
Publikováno v:
Molecular Microbiology. 99:794-807
Understanding the molecular strategies used by Mycobacterium tuberculosis to invade and persist within the host is of paramount importance to tackle the tuberculosis pandemic. Comparative genomic surveys have revealed that hadC, encoding a subunit of
Autor:
Alyssa Margolis, E. Jeffrey North, Victoria Jones, Annaïk Quémard, Jared J. Lindenberger, Donald R. Ronning, Richard E. Lee, Michael R. McNeil, Anna E. Grzegorzewicz, Mary Jackson, Patrick J. Brennan, Jana Korduláková, Nathalie Eynard
Publikováno v:
ACS Infectious Diseases. 1:91-97
Isoxyl and Thiacetazone are two antitubercular prodrugs formerly used in the clinical treatment of tuberculosis. Although both prodrugs have recently been shown to kill Mycobacterium tuberculosis through the inhibition of the dehydration step of the