Mass spectrometric quantification of urinary 6-sulfatoxymelatonin

Autor: Anna van der Veen, Ido P. Kema, Martijn van Faassen, Sonja L. van Ockenburg, Helma de Jong, Elisabeth G.E. de Vries

Publikováno v: Clinical chemistry and laboratory medicine, 59(1), 187-195. Walter de Gruyter GmbH

Objectives Regulators of circadian rhythm, including melatonin, influence fundamental biological processes. Measuring the melatonin metabolite 6-sulfatoxymelatonin in urine can estimate melatonin production. 6-sulfatoxymelatonin is mainly analyzed by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48472a5813bdd93e9ac1b867ed400335
https://doi.org/10.1515/cclm-2020-0455

Urinary Excretion of N1-Methylnicotinamide and N1-Methyl-2-Pyridone-5-Carboxamide and Mortality in Kidney Transplant Recipients

Autor: Johanna M. Geleijnse, Carolien P J Deen, Ido P. Kema, Stephan J. L. Bakker, M. Rebecca Heiner-Fokkema, António W Gomes-Neto, Anna van der Veen, Karin J Borgonjen-van den Berg

Publikováno v: Nutrients, 12(7):2059, 1-18. MDPI AG
Nutrients
Volume 12
Issue 7
Nutrients, 12(7)
Nutrients 12 (2020) 7
Nutrients, Vol 12, Iss 2059, p 2059 (2020)

It is unclear whether niacin nutritional status is a target for improvement of long-term outcome after renal transplantation. The 24-h urinary excretion of N1-methylnicotinamide (N1-MN), as a biomarker of niacin status, has previously been shown to b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c36d56564750d025a24bd495030196a
https://research.rug.nl/en/publications/5199fe23-889e-4920-977c-22b948ce0063

Urinary Excretion of N1-methyl-2-pyridone-5-carboxamide and N1-methylnicotinamide in Renal Transplant Recipients and Donors

Autor: Karin J Borgonjen-van den Berg, Carolien P J Deen, Anna van der Veen, Johanna M. Geleijnse, António W Gomes-Neto, M. Rebecca Heiner-Fokkema, Ido P. Kema, Stephan J. L. Bakker

Publikováno v: Journal of Clinical Medicine, 9(2)
Journal of Clinical Medicine
Volume 9
Issue 2
Journal of Clinical Medicine, Vol 9, Iss 2, p 437 (2020)
Journal of Clinical Medicine, 9(2). MDPI AG
Journal of Clinical Medicine 9 (2020) 2

N1-methylnicotinamide (N1-MN) and N1-methyl-2-pyridone-5-carboxamide (2Py) are successive end products of NAD+ catabolism. N1-MN excretion in 24-h urine is the established biomarker of niacin nutritional status, and recently shown to be reduced in re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffaf9302b46e7940f565636f21d93ba6
https://doi.org/10.3390/jcm9020437

Functional vitamin B-6 status and long-term mortality in renal transplant recipients

Autor: Ido P. Kema, Johanna M. Geleijnse, Stephan J. L. Bakker, Gerjan Navis, Else van den Berg, Ineke J. Riphagen, Anna van der Veen, Isidor Minović, António W Gomes-Neto, Claude van der Ley, Martijn van Faassen, Manfred Eggersdorfer

Publikováno v: American Journal of Clinical Nutrition, 106(6), 1366-1374. Oxford University Press
The American journal of clinical nutrition 106 (2017) 6
The American journal of clinical nutrition, 106(6), 1366-1374

Background: Low plasma concentrations of pyridoxal 5'-phosphate (PLP) are common in renal transplant recipients (RTRs) and confer increased risk of long-term mortality. To our knowledge, it is not known whether low plasma PLP concentrations have func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ca316cee62db31b67b4f43683a6836
https://doi.org/10.3945/ajcn.117.164012

Development and validation of a LC-MS/MS method for the establishment of reference intervals and biological variation for five plasma steroid hormones

Autor: Ido P. Kema, Wilhelmina H. A. de Jong, Anna van der Veen, André P van Beek, D.A. Janneke Dijck-Brouwer, Martijn van Faassen

Publikováno v: Clinical biochemistry, 68, 15-23. PERGAMON-ELSEVIER SCIENCE LTD

Background With liquid chromatography–tandem mass spectrometry (LC-MS/MS) increasingly being used for the quantification of steroid hormones , there is a need for studies that re-establish reference intervals and biological variation in well-define

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95fe6b5bf151261e97b32d8764cd46b
https://research.rug.nl/en/publications/cb03a808-00c4-4d6f-bc56-29811e9ac5e7