Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Anna, Zampetaki"'
Autor:
Sara G. Romeo, Ilaria Secco, Edoardo Schneider, Christina M. Reumiller, Celio X. C. Santos, Anna Zoccarato, Vishal Musale, Aman Pooni, Xiaoke Yin, Konstantinos Theofilatos, Silvia Cellone Trevelin, Lingfang Zeng, Giovanni E. Mann, Varun Pathak, Kevin Harkin, Alan W. Stitt, Reinhold J. Medina, Andriana Margariti, Manuel Mayr, Ajay M. Shah, Mauro Giacca, Anna Zampetaki
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The microvasculature plays a key role in tissue perfusion and exchange of gases and metabolites. In this study we use human blood vessel organoids (BVOs) as a model of the microvasculature. BVOs fully recapitulate key features of the human m
Externí odkaz:
https://doaj.org/article/353954422197417aa51e7b271e88c1e2
Autor:
Irina Zalivina, Temo Barwari, Xiaoke Yin, Sarah R. Langley, Javier Barallobre-Barreiro, Hiroko Wakimoto, Anna Zampetaki, Manuel Mayr, Metin Avkiran, Seda Eminaga
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 6, Iss , Pp 100056- (2023)
Background: Hypertrophic cardiomyopathy (HCM) is an autosomal dominant genetic disorder, characterized by cardiomyocyte hypertrophy, cardiomyocyte disarray and fibrosis, which has a prevalence of ∼1: 200–500 and predisposes individuals to heart f
Externí odkaz:
https://doaj.org/article/b8223816a67346999e77b33054cf0c71
Autor:
Chunbo Yang, Magdalini Eleftheriadou, Sophia Kelaini, Thomas Morrison, Marta Vilà González, Rachel Caines, Nicola Edwards, Andrew Yacoub, Kevin Edgar, Arya Moez, Aleksandar Ivetic, Anna Zampetaki, Lingfang Zeng, Fiona L. Wilkinson, Noemi Lois, Alan W. Stitt, David J. Grieve, Andriana Margariti
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Vascular endothelial cell (EC) dysfunction contributes to the occurrence of diabetic complications. Here the authors report that in diabetic conditions, upregulation of the RNA binding protein QKI-7 in ECs due to the imbalance of RNA splicing factors
Externí odkaz:
https://doaj.org/article/b856289dee3f46f7953a233bb72c1adc
Autor:
Silvia C. Trevelin, Anna Zampetaki, Greta Sawyer, Aleksandar Ivetic, Alison C. Brewer, Lesley Ann Smyth, Federica Marelli-Berg, Robert Köchl, Robert I. Lechler, Ajay M. Shah, Giovanna Lombardi
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Nox2 is a ROS-generating enzyme, deficiency of which increases suppression by Tregs in vitro and in an in vivo model of cardiac remodeling. As Tregs have emerged as a candidate therapy in autoimmunity and transplantation, we hypothesized that Nox2 de
Externí odkaz:
https://doaj.org/article/bf2e0a61fa26400587326b11e001c154
Autor:
Temo Barwari, Manuel Mayr, Herbert Tilg, Christoph Ebenbichler, Susana Sangiao-Alvarellos, Konstantinos Theofilatos, Clemens Gutmann, Kaloyan Takov, Bhawana Singh, Paula Juiz-Valiña, Bárbara María Varela-Rodríguez, Elena Outeiriño-Blanco, Elisa Duregotti, Anna Zampetaki, Lukas Lunger, María Jesús García-Brao, Peter Willeit, Enrique Mena, Stefan Kiechl, Fernando Cordido
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 2 (2020)
Introduction Bariatric surgery offers the most effective treatment for obesity, ameliorating or even reverting associated metabolic disorders, such as type 2 diabetes. We sought to determine the effects of bariatric surgery on circulating microRNAs (
Externí odkaz:
https://doaj.org/article/2d31736b24994b6284f02724b635df4c
Autor:
Anna Zampetaki, Lars Maegdefessel
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/df3a10dd6afc4e19ae11131ba5317c86
Autor:
Lazaros Lataniotis, Andreas Albrecht, Fatma O. Kok, Clinton A. L. Monfries, Lorena Benedetti, Nathan D. Lawson, Simon M. Hughes, Kathleen Steinhofel, Manuel Mayr, Anna Zampetaki
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract MicroRNAs (miRNAs) are important regulators of diverse physiological and pathophysiological processes. MiRNA families and clusters are two key features in miRNA biology. Here we explore the use of CRISPR/Cas9 as a powerful tool to delineate
Externí odkaz:
https://doaj.org/article/c6f1f4ed873b4bfc9c27edba831e3e8f
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/8e99740553f94c23b0bfd0d6282d0d9a
Autor:
Chunbo Yang, Magdalini Eleftheriadou, Sophia Kelaini, Thomas Morrison, Marta Vilà González, Rachel Caines, Nicola Edwards, Andrew Yacoub, Kevin Edgar, Arya Moez, Aleksandar Ivetic, Anna Zampetaki, Lingfang Zeng, Fiona L. Wilkinson, Noemi Lois, Alan W. Stitt, David J. Grieve, Andriana Margariti
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/0052053883264ab39db9bf4a7efba1c7
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
RNA has emerged as the prime target for diagnostics, therapeutics and the development of personalized medicine. In particular, the non-coding RNAs (ncRNAs) that do not encode proteins, display remarkable biochemical versatility. They can fold into co
Externí odkaz:
https://doaj.org/article/3b989be8cade4822961ea53bee7a87f8