Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Anna, Sokolovska"'
Autor:
Daniel S. Leventhal, Anna Sokolovska, Ning Li, Christopher Plescia, Starsha A. Kolodziej, Carey W. Gallant, Rudy Christmas, Jian-Rong Gao, Michael J. James, Andres Abin-Fuentes, Munira Momin, Christopher Bergeron, Adam Fisher, Paul F. Miller, Kip A. West, Jose M. Lora
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Synthetic biology can be used to create rationally designed living therapeutics. Here the authors engineer E. coli Nissle to target STING activation in antigen presenting cells for the treatment of solid tumors and demonstrate preclinical activity in
Externí odkaz:
https://doaj.org/article/c274837c940442a5b5b9051d086275aa
Autor:
Filip Janku, Jason Luke, Sarina Piha-Paul, Karl Lewis, James Strauss, Mary Varterasian, Anna Sokolovska, Richard Riese, Michael Armstrong, Claire Verschraegen, Aoife Brennan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/0d48c00422084969a3cbd19afb2696ad
Autor:
Jason J. Luke, Sarina A. Piha-Paul, Theresa Medina, Claire F. Verschraegen, Mary Varterasian, Aoife M. Brennan, Richard J. Riese, Anna Sokolovska, James Strauss, David L. Hava, Filip Janku
Publikováno v:
Clinical Cancer Research. :OF1-OF10
Purpose: SYNB1891 is a live, modified strain of the probiotic Escherichia coli Nissle 1917 (EcN) engineered to produce cyclic dinucleotides under hypoxia, leading to STimulator of INterferon Genes (STING) activation in phagocytic antigen-presenting c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93fa34e9a81e3f449d70ad34670bf3bd
https://doi.org/10.1158/1078-0432.ccr-23-0118
https://doi.org/10.1158/1078-0432.ccr-23-0118
Autor:
Ning Li, Fernando Canale, Camilla Basso, Anna Sokolovska, Michela Perotti, Michael James, Wenjie Jin, Jean-Philippe Theurillat, Daniel Leventhal, Kip West, Jose Lora, Federica Sallusto, Roger Geiger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/a0be3067cdbb4c43b08fc905e02ccd77
Autor:
Filip Janku, David L. Hava, James Strauss, Anna Sokolovska, Richard J. Riese, Aoife M. Brennan, Mary Varterasian, Claire F. Verschraegen, Theresa Medina, Sarina A. Piha-Paul, Jason J. Luke
Supplemental Figure 3. Serum cytokine levels in subjects receiving SYNB1891
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5708eb8d24c2eedd709b0743faf5dc13
https://doi.org/10.1158/1078-0432.23183903
https://doi.org/10.1158/1078-0432.23183903
Autor:
Filip Janku, David L. Hava, James Strauss, Anna Sokolovska, Richard J. Riese, Aoife M. Brennan, Mary Varterasian, Claire F. Verschraegen, Theresa Medina, Sarina A. Piha-Paul, Jason J. Luke
Supplemental Table 2. Tumor types and characteristics for Nanostring and immunofluorescence data analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e63cd59e34598ddc6dd5f2bdc764106
https://doi.org/10.1158/1078-0432.23183879
https://doi.org/10.1158/1078-0432.23183879
Autor:
Filip Janku, David L. Hava, James Strauss, Anna Sokolovska, Richard J. Riese, Aoife M. Brennan, Mary Varterasian, Claire F. Verschraegen, Theresa Medina, Sarina A. Piha-Paul, Jason J. Luke
Purpose:SYNB1891 is a live, modified strain of the probiotic Escherichia coli Nissle 1917 (EcN) engineered to produce cyclic dinucleotides under hypoxia, leading to STimulator of INterferon Genes (STING) activation in phagocytic antigen-presenting ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b62888fa04e40e6c1a5fc9b6706345
https://doi.org/10.1158/1078-0432.c.6664583
https://doi.org/10.1158/1078-0432.c.6664583
Autor:
Mridu Acharya, Anna Sokolovska, Jenny M. Tam, Kara L. Conway, Caroline Stefani, Fiona Raso, Subhankar Mukhopadhyay, Marianela Feliu, Elahna Paul, John Savill, Richard O. Hynes, Ramnik J. Xavier, Jatin M. Vyas, Lynda M. Stuart, Adam Lacy-Hulbert
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Integrins can regulate antigen-specific and innate immune receptor signalling, thereby affecting immune cell function. Here the authors show that avß3 integrin controls Toll-like receptor (TLR) signalling by regulating its trafficking to limit TLR-m
Externí odkaz:
https://doaj.org/article/dc8efeea8b80409f8e4a56aef9dd4da0
Autor:
Timothy K. Lu, Andres Cubillos-Ruiz, Jose M. Lora, Tingxi Guo, James J. Collins, Paul F. Miller, Anna Sokolovska
Publikováno v:
Nature Reviews Drug Discovery. 20:941-960
The steadfast advance of the synthetic biology field has enabled scientists to use genetically engineered cells, instead of small molecules or biologics, as the basis for the development of novel therapeutics. Cells endowed with synthetic gene circui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1689880d9c6a8d180bf1ae70cc36a849
https://doi.org/10.1038/s41573-021-00285-3
https://doi.org/10.1038/s41573-021-00285-3
Autor:
Natalie Artzi, Sidi A. Bencherif, Rachel Berryman, Khushbu Bhatt, Aoife M. Brennan, Sue Anne Chew, Alexander M. Cryer, Serena Danti, Nicholas DePatie, Sashana Dixon, Loek J. Eggermont, Samantha C. Emery, Reilly Fankhauser, Kristin Huntoon, Vincent M. Isabella, Wen Jiang, Emily M. Jordan, Betty Y.S. Kim, Stephen J. Kron, Rajan P. Kulkarni, Amrendra Kumar, DaeYong Lee, Steve Seung-Young Lee, Ning Li, Olivia M. Lucero, Mario Milazzo, Miles A. Miller, Xuan Mu, Thomas S.C. Ng, Joanna Pagacz, Praseet Poduval, Jai Prakash, Matthew Schrier, Kai Shi, Amit Singh, Anna Sokolovska, Alice Tran, Malav Trivedi, Irene Uboldi, Anna E. Vilgelm, Kevin P. Weller, Yi-Chien Wu, Yu Shrike Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cb44dcb1b5f0eab7c79c2c670810267
https://doi.org/10.1016/b978-0-323-90949-5.09989-7
https://doi.org/10.1016/b978-0-323-90949-5.09989-7