Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Anna, Shiriaeva"'
Autor:
Michael W. Martynowycz, Anna Shiriaeva, Max T. B. Clabbers, William J. Nicolas, Sara J. Weaver, Johan Hattne, Tamir Gonen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Here, authors demonstrate a method for milling vitrified biological material. Using correlative fluorescence and electron microscopy images, MicroED data is collected for the adenosine receptor.
Externí odkaz:
https://doaj.org/article/16fb1d2c79834624ba0f41611c4745a4
Publikováno v:
IUCrJ, Vol 9, Iss 2, Pp 169-179 (2022)
This article documents a keynote seminar presented at the IUCr Congress in Prague, 2021. The cryo-EM method microcrystal electron diffraction is described and put in the context of macromolecular electron crystallography from its origins in 2D crysta
Externí odkaz:
https://doaj.org/article/5c7e2f9bb31c431b9c4c35cf12a71f50
Autor:
Anna Maikova, Pierre Boudry, Anna Shiriaeva, Aleksandra Vasileva, Anaïs Boutserin, Sofia Medvedeva, Ekaterina Semenova, Konstantin Severinov, Olga Soutourina
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems provide prokaryotes with efficient protection against foreign nucleic acid invaders. We have recently demonstrated the defensive interference
Externí odkaz:
https://doaj.org/article/a1a07cf6296041e9ad107cf56f8087f0
Autor:
Andrii Ishchenko, Benjamin Stauch, Gye Won Han, Alexander Batyuk, Anna Shiriaeva, Chufeng Li, Nadia Zatsepin, Uwe Weierstall, Wei Liu, Eriko Nango, Takanori Nakane, Rie Tanaka, Kensuke Tono, Yasumasa Joti, So Iwata, Isabel Moraes, Cornelius Gati, Vadim Cherezov
Publikováno v:
IUCrJ, Vol 6, Iss 6, Pp 1106-1119 (2019)
Rational structure-based drug design (SBDD) relies on the availability of a large number of co-crystal structures to map the ligand-binding pocket of the target protein and use this information for lead-compound optimization via an iterative process.
Externí odkaz:
https://doaj.org/article/4ed362ab387b4cc5b84904da4feed3df
Autor:
Anna Shiriaeva, Daejin Park, Gyudong Kim, Yoonji Lee, Xiyan Hou, Dnyandev B. Jarhad, Gibae Kim, Jinha Yu, Young Eum Hyun, Woomi Kim, Zhan-Guo Gao, Kenneth A. Jacobson, Gye Won Han, Raymond C. Stevens, Lak Shin Jeong, Sun Choi, Vadim Cherezov
Publikováno v:
Journal of Medicinal Chemistry. 65:11648-11657
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b6f79bf66b85c0a0487a8a2f2f7e352
https://doi.org/10.1021/acs.jmedchem.2c00462
https://doi.org/10.1021/acs.jmedchem.2c00462
Autor:
Fumiaki Ito, Ana L. Alvarez-Cabrera, Shiheng Liu, Hanjing Yang, Anna Shiriaeva, Z. Hong Zhou, Xiaojiang S. Chen
Publikováno v:
Science advances. 9(1)
Human APOBEC3G (A3G) is a virus restriction factor that inhibits HIV-1 replication and triggers lethal hypermutation on viral reverse transcripts. HIV-1 viral infectivity factor (Vif) breaches this host A3G immunity by hijacking a cellular E3 ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc7d0f1dd9475bc53926be29c16fcf5
https://pubmed.ncbi.nlm.nih.gov/36598981
https://pubmed.ncbi.nlm.nih.gov/36598981
Autor:
Raphaël, Bolteau, Romain, Duroux, Amélie, Laversin, Brandon, Vreulz, Anna, Shiriaeva, Benjamin, Stauch, Gye Won, Han, Vadim, Cherezov, Nicolas, Renault, Amélie, Barczyk, Séverine, Ravez, Mathilde, Coevoet, Patricia, Melnyk, Maxime, Liberelle, Saïd, Yous
Publikováno v:
European journal of medicinal chemistry. 241
The past fifty years have been marked by the surge of neurodegenerative diseases. Unfortunately, current treatments are only symptomatic. Hence, the search for new and innovative therapeutic targets for curative treatments becomes a major challenge.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9dbcd2e0b44d5188113542cf70cf8484
https://pubmed.ncbi.nlm.nih.gov/35933788
https://pubmed.ncbi.nlm.nih.gov/35933788
Autor:
Konstantin Kuznedelov, Natalia Morozova, Sofya Medvedeva, Alexandr Kirillov, Konstantin Severinov, Eugene V. Koonin, Matvey Kolesnik, Leonid Minakhin, Ekaterina Semenova, Anna Shiriaeva, Kira S. Makarova, Sergei Borukhov, Ishita Jain
Type VI CRISPR-Cas systems are the only CRISPR variety that cleaves exclusively RNA1,2. In addition to the CRISPR RNA (crRNA)-guided, sequence-specific binding and cleavage of target RNAs, such as phage transcripts, the type VI effector, Cas13, cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b53841ca3340abaf0b47fa866ecf57b9
https://doi.org/10.21203/rs.3.rs-1068910/v1
https://doi.org/10.21203/rs.3.rs-1068910/v1
Autor:
Ishita Jain, Matvey Kolesnik, Leonid Minakhin, Natalia Morozova, Anna Shiriaeva, Alexandr Kirillov, Sofia Medvedeva, Konstantin Kuznedelov, Sergei Borukhov, Kira S. Makarova, Eugene V. Koonin, Konstantin Severinov, Ekaterina Semenova
Type VI CRISPR-Cas systems are the only CRISPR variety that cleaves exclusively RNA1,2. In addition to the CRISPR RNA (crRNA)-guided, sequence-specific binding and cleavage of target RNAs, such as phage transcripts, the type VI effector, Cas13, cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c369fce9b3a57b7a278a411fcac11a8
https://doi.org/10.1101/2021.11.10.468108
https://doi.org/10.1101/2021.11.10.468108
Autor:
Konstantin Severinov, Sofia Medvedeva, Olga Soutourina, Aleksandra Vasileva, Anna Maikova, Pierre Boudry, Anaïs Boutserin, Anna Shiriaeva, Ekaterina Semenova
Publikováno v:
mBio
mBio, Vol 12, Iss 4 (2021)
mBio, Vol 12, Iss 4 (2021)
CRISPR ( c lustered r egularly i nterspaced s hort p alindromic r epeats)-Cas (CRISPR-associated) systems provide prokaryotes with efficient protection against foreign nucleic acid invaders. We have recently demonstrated the defensive interference fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806b7c91f2138543f94f25d1240111fe
https://doi.org/10.1128/mbio.02136-21
https://doi.org/10.1128/mbio.02136-21