Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Anna, Sebestyén"'
Autor:
Ildikó Krencz, Dániel Sztankovics, Anna Sebestyén, Judit Pápay, Titanilla Dankó, Dorottya Moldvai, Elmar Lutz, Andras Khoor
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
RICTOR gene, which encodes the scaffold protein of mTORC2, can be amplified in various tumor types, including squamous cell carcinoma (SCC) of the lung. RICTOR amplification can lead to hyperactivation of mTORC2 and may serve as a targetable genetic
Externí odkaz:
https://doaj.org/article/fc3d684fdaff4c96b26aca54c6f8cf21
Autor:
Dániel Sztankovics, Dorottya Moldvai, Gábor Petővári, Titanilla Dankó, Fatime Szalai, Risa Miyaura, Viktória Varga, Noémi Nagy, Gergő Papp, Judit Pápay, Ildikó Krencz, Anna Sebestyén
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
The increasing knowledge of molecular alterations in malignancies, including mutations and regulatory failures in the mTOR (mechanistic target of rapamycin) signaling pathway, highlights the importance of mTOR hyperactivity as a validated target in c
Externí odkaz:
https://doaj.org/article/50d1c7653f534df2bad19730c717af5b
Autor:
Dániel Sztankovics, Ildikó Krencz, Dorottya Moldvai, Titanilla Dankó, Ákos Nagy, Noémi Nagy, Gábor Bedics, András Rókusz, Gergő Papp, Anna-Mária Tőkés, Judit Pápay, Zoltán Sápi, Katalin Dezső, Csaba Bödör, Anna Sebestyén
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Alterations in mTOR signalling molecules, including RICTOR amplification, have been previously described in many cancers, particularly associated with poor prognosis. In this study, RICTOR copy number variation (CNV) results of diagnostic ne
Externí odkaz:
https://doaj.org/article/d916b489a8c1402d8ae70fac8a29c2d2
Autor:
Dorottya Kocsis, Shanmugam Dhinakaran, Divyam Pandey, András József Laki, Mária Laki, Dániel Sztankovics, Miléna Lengyel, Judit Vrábel, Márton Bese Naszlady, Anna Sebestyén, Jeyaraj Ponmozhi, István Antal, Franciska Erdő
Publikováno v:
Scientia Pharmaceutica, Vol 92, Iss 2, p 35 (2024)
Organ-on-a-chip technologies show exponential growth driven by the need to reduce the number of experimental animals and develop physiologically relevant human models for testing drugs. In vitro, microfluidic devices should be carefully designed and
Externí odkaz:
https://doaj.org/article/ea0980236beb400080383eb5034f6059
Autor:
Viktória Zsiros, Nikolett Dóczi, Gábor Petővári, Alexandra Pop, Zsófia Erdei, Anna Sebestyén, Anna L. Kiss
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Previously, we showed that after Freund’s adjuvant-induced peritonitis, rat mesothelial cells regain their epithelial phenotype through mesenchymal-epithelial transition (MET) accompanied by autophagy. Since bone morphogenetic proteins (BM
Externí odkaz:
https://doaj.org/article/f29579322946424fb3b8d3485f892a0e
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Externí odkaz:
https://doaj.org/article/fdf98016123f484ebafd36094ae94e73
Autor:
Henriette Farkas, Csilla Máj, István Kenessey, Anna Sebestyén, Ildikó Krencz, Judit Pápay, László Cervenak
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 18, Iss 1, Pp 1-8 (2022)
Abstract Background Hereditary angioedema (HAE) is a rare, life-threatening disease. The knowledge about the molecular pathogenesis of HAE has derived mainly from investigating blood samples. However, limited data are available on the role of the mol
Externí odkaz:
https://doaj.org/article/029d483150c043a688edcc0810c0c4a7
Autor:
Lóránd Váncza, Katalin Karászi, Bálint Péterfia, Lilla Turiák, Katalin Dezső, Anna Sebestyén, Andrea Reszegi, Gábor Petővári, András Kiss, Zsuzsanna Schaff, Kornélia Baghy, Ilona Kovalszky
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/3f8a394011a046918cdf4168a40b7f33
Autor:
András Fodor, Claudia Hess, Petra Ganas, Zsófia Boros, János Kiss, László Makrai, Károly Dublecz, László Pál, László Fodor, Anna Sebestyén, Michael G. Klein, Eustachio Tarasco, Manjusha M. Kulkarni, Bradford S. McGwire, Tibor Vellai, Michael Hess
Publikováno v:
Antibiotics, Vol 12, Iss 9, p 1462 (2023)
Anti-microbial peptides provide a powerful toolkit for combating multidrug resistance. Combating eukaryotic pathogens is complicated because the intracellular drug targets in the eukaryotic pathogen are frequently homologs of cellular structures of v
Externí odkaz:
https://doaj.org/article/cfbfa64ad3e74b419f062d1fee1593d1
Autor:
Gábor Petővári, Gábor Tóth, Lilla Turiák, Anna L. Kiss, Krisztina Pálóczi, Anna Sebestyén, Adrián Pesti, András Kiss, Kornélia Baghy, Katalin Dezső, Tibor Füle, Péter Tátrai, Ilona Kovalszky, Andrea Reszegi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13996 (2023)
Tumors are intricate ecosystems where cancer cells and non-malignant stromal cells, including cancer-associated fibroblasts (CAFs), engage in complex communication. In this study, we investigated the interaction between poorly (HLE) and well-differen
Externí odkaz:
https://doaj.org/article/4d3f5f5114344ec0baf705f255eb0142