Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Anna, Sebestyén"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Evans, Harriet, O’Sullivan, Brendan, Hughes, Frances, Charles, Kathryn, Robertson, Lee, Taniere, Philippe, Diaz-Cano, Salvador J.
Immune checkpoint blockade (ICB) drugs are a novel, effective treatment for advanced urothelial carcinoma. Worldwide, several different ICB drugs are approved, each developed and clinically validated with a specific PD-L1 compound diagnostic assay. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134c4171ddadca1a35c91f7b72cdb1a6
Publikováno v:
Cancer metastasis reviews. 40(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e234bcea886423bd656ba9538e1a7b0c
https://pubmed.ncbi.nlm.nih.gov/35133559
https://pubmed.ncbi.nlm.nih.gov/35133559
Autor:
Ildikó Krencz, Dániel Sztankovics, Anna Sebestyén, Judit Pápay, Titanilla Dankó, Dorottya Moldvai, Elmar Lutz, Andras Khoor
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
RICTOR gene, which encodes the scaffold protein of mTORC2, can be amplified in various tumor types, including squamous cell carcinoma (SCC) of the lung. RICTOR amplification can lead to hyperactivation of mTORC2 and may serve as a targetable genetic
Externí odkaz:
https://doaj.org/article/fc3d684fdaff4c96b26aca54c6f8cf21
Autor:
Dániel Sztankovics, Dorottya Moldvai, Gábor Petővári, Titanilla Dankó, Fatime Szalai, Risa Miyaura, Viktória Varga, Noémi Nagy, Gergő Papp, Judit Pápay, Ildikó Krencz, Anna Sebestyén
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
The increasing knowledge of molecular alterations in malignancies, including mutations and regulatory failures in the mTOR (mechanistic target of rapamycin) signaling pathway, highlights the importance of mTOR hyperactivity as a validated target in c
Externí odkaz:
https://doaj.org/article/50d1c7653f534df2bad19730c717af5b
Autor:
Dániel Sztankovics, Ildikó Krencz, Dorottya Moldvai, Titanilla Dankó, Ákos Nagy, Noémi Nagy, Gábor Bedics, András Rókusz, Gergő Papp, Anna-Mária Tőkés, Judit Pápay, Zoltán Sápi, Katalin Dezső, Csaba Bödör, Anna Sebestyén
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Alterations in mTOR signalling molecules, including RICTOR amplification, have been previously described in many cancers, particularly associated with poor prognosis. In this study, RICTOR copy number variation (CNV) results of diagnostic ne
Externí odkaz:
https://doaj.org/article/d916b489a8c1402d8ae70fac8a29c2d2
Autor:
Dorottya Kocsis, Shanmugam Dhinakaran, Divyam Pandey, András József Laki, Mária Laki, Dániel Sztankovics, Miléna Lengyel, Judit Vrábel, Márton Bese Naszlady, Anna Sebestyén, Jeyaraj Ponmozhi, István Antal, Franciska Erdő
Publikováno v:
Scientia Pharmaceutica, Vol 92, Iss 2, p 35 (2024)
Organ-on-a-chip technologies show exponential growth driven by the need to reduce the number of experimental animals and develop physiologically relevant human models for testing drugs. In vitro, microfluidic devices should be carefully designed and
Externí odkaz:
https://doaj.org/article/ea0980236beb400080383eb5034f6059
Autor:
Viktória Zsiros, Nikolett Dóczi, Gábor Petővári, Alexandra Pop, Zsófia Erdei, Anna Sebestyén, Anna L. Kiss
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Previously, we showed that after Freund’s adjuvant-induced peritonitis, rat mesothelial cells regain their epithelial phenotype through mesenchymal-epithelial transition (MET) accompanied by autophagy. Since bone morphogenetic proteins (BM
Externí odkaz:
https://doaj.org/article/f29579322946424fb3b8d3485f892a0e
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Externí odkaz:
https://doaj.org/article/fdf98016123f484ebafd36094ae94e73
Autor:
Henriette Farkas, Csilla Máj, István Kenessey, Anna Sebestyén, Ildikó Krencz, Judit Pápay, László Cervenak
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 18, Iss 1, Pp 1-8 (2022)
Abstract Background Hereditary angioedema (HAE) is a rare, life-threatening disease. The knowledge about the molecular pathogenesis of HAE has derived mainly from investigating blood samples. However, limited data are available on the role of the mol
Externí odkaz:
https://doaj.org/article/029d483150c043a688edcc0810c0c4a7