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Akademický článek

Detectable ctDNA at the time of treatment cessation of ipilimumab and nivolumab for toxicity predicts disease progression in advanced melanoma patients

Autor: Lydia Warburton, Anna Reid, Benhur Amanuel, Leslie Calapre, Michael Millward, Elin Gray

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

BackgroundImmune checkpoint inhibition (ICI) has led to unprecedented outcomes for melanoma patients but is associated with toxicity. ICI resumption after high grade irAEs poses a significant challenge in the clinical management of melanoma patients

Externí odkaz: https://doaj.org/article/18f274af506c4524b326903196863333

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Akademický článek

CTLA4 mRNA is downregulated by miR-155 in regulatory T cells, and reduced blood CTLA4 levels are associated with poor prognosis in metastatic melanoma patients

Autor: Prasanna Kumar Vaddi, Douglas Grant Osborne, Andrew Nicklawsky, Nazanin K. Williams, Dinoop Ravindran Menon, Derek Smith, Jonathan Mayer, Anna Reid, Joanne Domenico, Giang Huong Nguyen, William A. Robinson, Melanie Ziman, Dexiang Gao, Zili Zhai, Mayumi Fujita

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is an immune checkpoint expressed in regulatory T (Treg) cells and activated T lymphocytes. Despite its potential as a treatment strategy for melanoma, CTLA-4 inhibition has limited efficacy. Using

Externí odkaz: https://doaj.org/article/b7d65bd3cb3040ed8b2065be56840d1d

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Akademický článek

Copper chelation in patients with hypertrophic cardiomyopathy

Autor: Matthias Schmitt, Anna Reid, David Clark, Simon Ray, Christopher Miller, Garth Cooper, John Peter Farrant, Rahul Polturi

Publikováno v: Open Heart, Vol 9, Iss 1 (2022)

Externí odkaz: https://doaj.org/article/f923ca8675514a1695424f663a80b89f

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Akademický článek

The gestational diabetes future diabetes prevention study (GODDESS): A partially randomised feasibility controlled trial.

Autor: Judith Parsons, Rita Forde, Anna Brackenridge, Katharine F Hunt, Khalida Ismail, Trevor Murrells, Anna Reid, Helen Rogers, Rebecca Rogers, Angus Forbes

Publikováno v: PLoS ONE, Vol 17, Iss 12, p e0273992 (2022)

ObjectivesTo assess the feasibility of an ante- and post-natal lifestyle intervention for women with gestational diabetes mellitus (GDM) to reduce type 2 diabetes risk.DesignA partially randomised patient preference feasibility trial.SettingDiabetes

Externí odkaz: https://doaj.org/article/02c09c8467b94fbcbc9d6e534d45deac

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The journal of cardiovascular computed tomography

Publikováno v: Journal of Cardiovascular Computed Tomography, 17(2), 86-95. ELSEVIER SCIENCE INC
Pontone, G, Mushtaq, S, Al'aref, S J, Andreini, D, Baggiano, A, Canan, A, Cavalcante, J L, Chelliah, A, Chen, M, Choi, A, Damini, D, De cecco, C N, Farooqi, K M, Ferencik, M, Feuchtner, G, Hecht, H, Gransar, H, Kolossváry, M, Leipsic, J, Lu, M T, Marwan, M, Ng, M, Maurovich-Horvat, P, Nagpal, P, Nicol, E, Weir-Mccall, J, Whelton, S P, Williams, M C, Reid, A, Fairbairn, T A, Villines, T, Vliegenthart, R & Arbab-Zadeh, A 2023, ' The Journal of Cardiovascular Computed Tomography: A year in review: 2022 ', Journal of Cardiovascular Computed Tomography . https://doi.org/10.1016/j.jcct.2023.03.001

This review aims to summarize key articles published in the Journal of Cardiovascular Computed Tomography (JCCT) in 2022, focusing on those that had the most scientific and educational impact. The JCCT continues to expand; the number of submissions,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b6bbd6d803b96b3f68fb9a14df4b88
https://doi.org/10.1016/j.jcct.2023.03.001

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Geometric differences of the mitral valve apparatus in atrial and ventricular functional mitral regurgitation

Autor: Anna Reid, Sagit Ben Zekry, Christopher Naoum, Hidenobou Takagi, Christopher Thompson, Marcelo Godoy, Malcolm Anastasius, Stephanie Tarazi, Mansi Turaga, Robert Boone, John Webb, Jonathon Leipsic, Philipp Blanke

Publikováno v: Journal of Cardiovascular Computed Tomography. 16:431-441

Functional mitral regurgitation (FMR) occurs in patients with annular dilation (atrial, aFMR) or patients with left ventricular (LV) disease (ventricular, vFMR). Meticulous understanding of the mechanisms underpinning regurgitation is crucial to opti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f4bd4178ba4c76ef503fbadbf9a345
https://doi.org/10.1016/j.jcct.2022.02.008

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Let there be light! The meteoric rise of cardiac imaging

Autor: Anna Reid, Marc Richard Dweck

Publikováno v: Heart. 108:780-786

Imaging plays a central role in modern cardiovascular practice. It is a field characterised by exciting technological advances that have shaped our understanding of pathology and led to major improvements in patient diagnosis and care. The UK has pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96feb1dffceac9961b14e0c70477798c
https://doi.org/10.1136/heartjnl-2021-320147

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Akademický článek

Paul Nash’s Geological Enigma

Autor: Anna Reid

Publikováno v: British Art Studies, Iss 10 (2018)

This essay explores the attunement of Nash’s work to pioneering geophysical research in England, connections which have not yet been fully recognized. In a context of the early-to-mid twentieth century, when geophysicists read the startling radioac

Externí odkaz: https://doaj.org/article/d2fef014accc4ef6bd03de097c46d2db

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