Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anna, Orekhova"'
Autor:
Mariela Cortés-López, Laura Schulz, Mihaela Enculescu, Claudia Paret, Bea Spiekermann, Mathieu Quesnel-Vallières, Manuel Torres-Diz, Sebastian Unic, Anke Busch, Anna Orekhova, Monika Kuban, Mikhail Mesitov, Miriam M. Mulorz, Rawan Shraim, Fridolin Kielisch, Jörg Faber, Yoseph Barash, Andrei Thomas-Tikhonenko, Kathi Zarnack, Stefan Legewie, Julian König
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Multiple alternative splicing events in CD19 mRNA have been associated with resistance/relapse to CD19 CAR-T therapy in patients with B cell malignancies. Here, by combining patient data and a high-throughput mutagenesis screen, the authors identify
Externí odkaz:
https://doaj.org/article/c08d347a8dc943b8ab905da6ad76b36d
Autor:
Agnieszka Magdalena Rygiel, Lara Sophie Unger, Franziska Lena Sörgel, Emmanuelle Masson, Ryotaro Matsumoto, Maren Ewers, Jian-Min Chen, Peter Bugert, Louis Buscail, Tomasz Gambin, Grzegorz Oracz, Maria Winiewska-Szajewska, Agnieszka Mianowska, Jarosław Poznanski, Joanna Kosińska, Piotr Stawinski, Rafał Płoski, Dorota Koziel, Stanisław Gluszek, Helmut Laumen, Fredrik Lindgren, J. Matthias Löhr, Anna Orekhova, Vinciane Rebours, Jonas Rosendahl, Andrea Párniczky, Péter Hegyi, Akira Sasaki, Fumiya Kataoka, Yu Tanaka, Shin Hamada, Miklós Sahin-Tóth, Eszter Hegyi, Claude Férec, Atsushi Masamune, Heiko Witt
Publikováno v:
Pancreatology
OBJECTIVE: Non-alcoholic chronic pancreatitis (NACP) frequently develops in the setting of genetic susceptibility associated with alterations in genes that are highly expressed in the pancreas. However, the genetic basis of NACP remains unresolved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf0445892bd941d18a4c220ba4dab66
https://doi.org/10.1016/j.pan.2022.04.015
https://doi.org/10.1016/j.pan.2022.04.015
Autor:
Miklós Sahin-Tóth, Zsanett Jancsó, Anna Orekhova, Andrea Geisz, Dóra Mosztbacher, Balazs Csaba Nemeth, Alexandra Demcsák
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
The activation peptide of mammalian trypsinogens typically contains a tetra-aspartate motif (positions P2–P5 in Schechter–Berger numbering) that inhibits autoactivation and facilitates activation by enteropeptidase. This evolutionary mechanism pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17745a06735c19b18bfde36450b0d96
https://doi.org/10.1152/ajpgi.00265.2021
https://doi.org/10.1152/ajpgi.00265.2021
Publikováno v:
Gastroenterology. 164:684-687.e4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc84bd73a0873c5a82322b0472c8e91a
https://doi.org/10.1053/j.gastro.2023.01.004
https://doi.org/10.1053/j.gastro.2023.01.004
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 318:G694-G704
Alcoholic pancreatitis is a multifactorial, progressive, inflammatory disorder of the pancreas. Alcohol initiates pancreatitis and promotes its progression in the context of genetic susceptibility and/or other environmental risk factors such as smoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4409f31cd86e4d71ba6b97a7835bda99
https://doi.org/10.1152/ajpgi.00007.2020
https://doi.org/10.1152/ajpgi.00007.2020
Autor:
Stefan Legewie, Kathi Zarnack, Claudia Paret, Mariela Cortés-López, Jörg Faber, Fridolin Kielisch, Mathieu Quesnel-Vallières, Anna Orekhova, Andrei Thomas-Tikhonenko, Anke Busch, Mihaela Enculescu, Julian König, Laura Schulz, Bea Spiekermann, Manuel Torres-Diz, Yoseph Barash
During CART-19 immunotherapy for B-cell acute lymphoblastic leukaemia (B-ALL), many patients relapse due to loss of the cognate CD19 epitope. Since epitope loss can be caused by aberrant CD19 exon 2 processing, we herein investigate the regulatory co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78ef49a673da74a4df65fb6f1b26d7d4
https://doi.org/10.1101/2021.10.08.463671
https://doi.org/10.1101/2021.10.08.463671
Autor:
Mariela, Cortés-López, Laura, Schulz, Mihaela, Enculescu, Claudia, Paret, Bea, Spiekermann, Mathieu, Quesnel-Vallières, Manuel, Torres-Diz, Sebastian, Unic, Anke, Busch, Anna, Orekhova, Monika, Kuban, Mikhail, Mesitov, Miriam M, Mulorz, Rawan, Shraim, Fridolin, Kielisch, Jörg, Faber, Yoseph, Barash, Andrei, Thomas-Tikhonenko, Kathi, Zarnack, Stefan, Legewie, Julian, König
Publikováno v:
Nature communications. 13(1)
Following CART-19 immunotherapy for B-cell acute lymphoblastic leukaemia (B-ALL), many patients relapse due to loss of the cognate CD19 epitope. Since epitope loss can be caused by aberrant CD19 exon 2 processing, we herein investigate the regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3adc23a1f7e72bbc70f381f619ca75e5
https://pubmed.ncbi.nlm.nih.gov/36138008
https://pubmed.ncbi.nlm.nih.gov/36138008
Autor:
Anna Orekhova, Tobias Schwarz
Publikováno v:
Orekhova, A & Schwarz, T 2021, ' Synovial lipomatosis of the stifle joint in a dog ', Vet Record Case Reports . https://doi.org/10.1002/vrc2.163
Synovial lipomatosis has been described as a rare disease of the synovial membrane in humans. This report represents a synovial lipomatosis case of the left stifle joint in a dog, diagnosed by MRI and validated by histopathologic examination. Synovia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e92f04d6c7b54d4b1a3171674ab3d0b
https://doi.org/10.1002/vrc2.163
https://doi.org/10.1002/vrc2.163
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Alcoholic pancreatitis is a multifactorial, progressive, inflammatory disorder of the pancreas. Alcohol initiates pancreatitis and promotes its progression in the context of genetic susceptibility and/or other environmental risk factors such as smoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee8ccb017d767d231a397df173b6342f
https://pubmed.ncbi.nlm.nih.gov/32116022
https://pubmed.ncbi.nlm.nih.gov/32116022
Autor:
Maisam Abu-El-Haija, Balázs Németh, Tyler Thompson, Shannon Nortman, Péter Hegyi, Wenying Zhang, Anna Orekhova
Publikováno v:
Gut
We read the publication written by Lin et al 1 with great interest. The authors suggest that the majority of functionally defective carboxypeptidase A1 ( CPA1) mutations can elicit reduced expression due to nonsense-mediated decay (NMD) and therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01dc19b439518fd9361d8af63d720a79
https://europepmc.org/articles/PMC8596457/
https://europepmc.org/articles/PMC8596457/