Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anna, Kucharski"'
Autor:
Matthew Zammit, Chien-Min Kao, Hannah J. Zhang, Hsiu-Ming Tsai, Nathanial Holderman, Samuel Mitchell, Eve Tanios, Mohammed Bhuiyan, Richard Freifelder, Anna Kucharski, William N. Green, Jogeshwar Mukherjee, Chin-Tu Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15510 (2023)
Positron emission tomography (PET) radioligands that bind with high-affinity to α4β2-type nicotinic receptors (α4β2Rs) allow for in vivo investigations of the mechanisms underlying nicotine addiction and smoking cessation. Here, we investigate th
Externí odkaz:
https://doaj.org/article/529a1aeb78e440c383ad1f97ae4b8642
Autor:
Hannah J. Zhang, Matthew Zammit, Chien-Min Kao, Anitha P. Govind, Samuel Mitchell, Nathanial Holderman, Mohammed Bhuiyan, Richard Freifelder, Anna Kucharski, Xiaoxi Zhuang, Jogeshwar Mukherjee, Chin-Tu Chen, William N. Green
Publikováno v:
J Neurosci
A question relevant to nicotine addiction is how nicotine and other nicotinic receptor membrane-permeant ligands, such as the anti-smoking drug varenicline (Chantix), distribute in brain. Ligands, like varenicline, with high pKaand high affinity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f4cb8c695d85830f981fd20a41960c
https://europepmc.org/articles/PMC9838697/
https://europepmc.org/articles/PMC9838697/
Akademický článek
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Publikováno v:
Physics in medicine and biology. 68(1)
Objective. In this work, the irradiation of natural titanium foils in the beam-stop of a compact medical cyclotron, an IBA CYCLONE 18/9, is simulated to assess the efficacy of using a beam-stop as a target holder, and using two different target geome
Autor:
Inna Gertsenshteyn, Boris Epel, Amandeep Ahluwalia, Heejong Kim, Xiaobing Fan, Eugene Barth, Marta Zamora, Erica Markiewicz, Hsui-Ming Tsai, Subramanian Sundramoorthy, Lara Leoni, John Lukens, Mohammed Bhuiyan, Richard Freifelder, Anna Kucharski, Mihai Giurcanu, Brian Roman, Gregory Karczmar, Chien-Min Kao, Howard Halpern, Chin-Tu Chen
Publikováno v:
European journal of nuclear medicine and molecular imaging. 49(12)
To identify the optimal threshold insup18/supF-fluoromisonidazole (FMISO) PET images to accurately locate tumor hypoxia by using electron paramagnetic resonance imaging (pOsub2/subEPRI) as ground truth for hypoxia, defined by pOsub2/sub[Formula: see
Autor:
Brittany A. Broder, Mohammed P. Bhuiyan, Richard Freifelder, Hannah J. Zhang, Anna Kucharski, Marvin W. Makinen, David A. Rotsch, Chin-Tu Chen
Publikováno v:
Applied Radiation and Isotopes. 186:110270
Autor:
Brittany A, Broder, Mohammed P, Bhuiyan, Richard, Freifelder, Hannah J, Zhang, Anna, Kucharski, Marvin W, Makinen, David A, Rotsch, Chin-Tu, Chen
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 186
In this preliminary study, a procedure for synthesizing novel PET radiotracer vanadium-48-labeled-vanadyl acetylacetonate was developed, including radioisotope production via cyclotron, separation of
Autor:
Inna, Gertsenshteyn, Boris, Epel, Eugene, Barth, Lara, Leoni, Erica, Markiewicz, Hsiu-Ming, Tsai, Xiaobing, Fan, Mihai, Giurcanu, Darwin, Bodero, Marta, Zamora, Subramanian, Sundramoorthy, Heejong, Kim, Richard, Freifelder, Mohammed, Bhuiyan, Anna, Kucharski, Gregory, Karczmar, Chien-Min, Kao, Howard, Halpern, Chin-Tu, Chen
Publikováno v:
Radiol Imaging Cancer
PURPOSE: To enhance the spatial accuracy of fluorine 18 ((18)F) misonidazole (MISO) PET imaging of hypoxia by using dynamic contrast-enhanced (DCE) MR images as a basis for modifying PET images and by using electron paramagnetic resonance (EPR) parti
Autor:
August Stich, Ines Schmidt, Elena Katzowitsch, Heike Bruhn, Antje Fuß, Alexandra Miliu, Sarah Göllner, Tanja Schirmeister, Anna Kucharski, R. Luise Krauth-Siegel, Ulrike Holzgrabe
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:4526-4531
Human African Trypanosomiasis (HAT) is caused by two subspecies of the genus Trypanosoma, namely Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. The disease is fatal if left untreated and therapy is limited due to only five non-adequ
Autor:
Boris Epel, Heejong Kim, Richard Freifelder, Inna Gertsenshteyn, Chien-Min Kao, Eugene D. Barth, Mohammed Bhuiyan, Subramanian V. Sundramoorthy, Mihai Giurcanu, Darwin Bodero, Gregory S. Karczmar, Hsiu-Ming Tsai, Xiaobing Fan, Anna Kucharski, Chin-Tu Chen, Lara Leoni, Howard J. Halpern, Marta Zamora, Erica Markiewicz
Publikováno v:
Radiology: Imaging Cancer. 3:e200104
This study serves as a proof of concept for multimodal oxygen imaging in developing an algorithm to make fluorine 18 misonidazole PET more comparable with quantitative electron paramagnetic resonan...