Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Anna, Kovtun"'
Autor:
Anna KOVTUN, Marina KORDUBAN
Publikováno v:
Humanities science current issues. :548-554
Autor:
Stephanie Bergdolt, Anna Kovtun, Yvonne Hägele, Astrid Liedert, Thorsten Schinke, Michael Amling, Markus Huber-Lang, Anita Ignatius
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179512 (2017)
The anaphylatoxin receptor C5aR1 plays an important role not only in innate immune responses, but also in bone metabolism and fracture healing, being highly expressed on immune and bone cells, including osteoblasts and osteoclasts. C5aR1 induces oste
Externí odkaz:
https://doaj.org/article/77bcb5753f0644aebe52ca503de24622
Autor:
Melanie Haffner-Luntzer, Julia Kemmler, Verena Heidler, Katja Prystaz, Thorsten Schinke, Michael Amling, Anna Kovtun, Anna E Rapp, Anita Ignatius, Astrid Liedert
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159278 (2016)
The heparin-binding growth and differentiation factor midkine (Mdk) is proposed to negatively regulate osteoblast activity and bone formation in the adult skeleton. As Mdk-deficient mice were protected from ovariectomy (OVX)-induced bone loss, this f
Externí odkaz:
https://doaj.org/article/1c17257ca9324cfd979d1e405be25b4e
Autor:
Anna E. Rapp, Katja Prystaz, Stefan Rose-John, Kathrin Kaiser, Melanie Haffner-Luntzer, Astrid Liedert, Verena Fischer, Gudrun Strauss, Anita Ignatius, Georg H. Waetzig, Anna Kovtun
Publikováno v:
The American Journal of Pathology. 188:474-490
Bone healing is a complex process with closely linked phases of inflammation, regeneration, and remodeling. IL-6 may crucially regulate this process; however, the underlying mechanisms are unclear. IL-6 signals are transmitted via the transmembrane g
Autor:
Martina Gatzka, Ioanna Krikki, Melanie Haffner-Luntzer, Katja Prystaz, Titus J. Brinker, Verena Fischer, Anita Ignatius, Adelheid Hainzl, Carsten M. Kroeger, Anna Kovtun
Publikováno v:
The FASEB Journal. 32:1957-1968
Histone modifications critically contribute to the epigenetic orchestration of bone homeostasis-in part, by modifying the access of transcription factors to specific genes involved in the osteogenic differentiation process of bone marrow mesenchymal
Autor:
Julia Kemmler, Anne Dudeck, Thorsten Schinke, Anita Ignatius, Michael Amling, Johanna Kotrba, Jan Dudeck, Jochen Kroner, Sebastian Seitz, Julia Froebel, Joanna J. Messmann, Gudrun Strauss, Anna Kovtun
Publikováno v:
Journal of Bone and Mineral Research. 32:2431-2444
Mast cells, important sensor and effector cells of the immune system, may influence bone metabolism as their number is increased in osteoporotic patients. They are also present during bone fracture healing with currently unknown functions. Using a no
Autor:
Rebecca Wiegner, Anita Ignatius, Peter Radermacher, Anna Kovtun, Markus Huber-Lang, Stephanie Bergdolt
Publikováno v:
European Cells & Materials, Vol 32, Pp 152-162 (2016)
Europe PubMed Central
Europe PubMed Central
Delayed bone fracture healing and the formation of non-unions represent an important clinical problem, particularly in polytrauma patients who suffer from posttraumatic systemic inflammation. However, the underlying pathomechanisms remain unclear. Ne
Publikováno v:
Current Molecular Biology Reports. 2:101-111
Bone fracture healing is a tightly regulated process involving many cell types, mediators, and signaling pathways and is still not well understood. During decades, bone healing was mainly studied in large animals, including dogs, rabbits, or sheep. I
Autor:
Katrin S. Lips, Christian Heiss, Lutz Dürselen, Vivien Kauschke, Jonas Sender, Anna Kovtun, Marian Kampschulte, Malte Haupt
Publikováno v:
International Immunopharmacology. 29:208-214
Butyrylcholinesterase (BChE) degrades acetylcholine in addition to acetylcholinesterase (AChE) which is involved in embryonic development of limbs. Since BChE is expressed by osteoblast-like cells we asked whether it is functional in adult bone remod
Autor:
Melanie, Haffner-Luntzer, Anna, Kovtun, Verena, Fischer, Katja, Prystaz, Adelheid, Hainzl, Carsten M, Kroeger, Ioanna, Krikki, Titus J, Brinker, Anita, Ignatius, Martina, Gatzka
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(4)
Histone modifications critically contribute to the epigenetic orchestration of bone homeostasis-in part, by modifying the access of transcription factors to specific genes involved in the osteogenic differentiation process of bone marrow mesenchymal