Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Anna, Hultberg"'
Autor:
Monica Carpenedo, Catherine M Broome, Vickie Mcdonald, Yoshitaka Miyakawa, David Kuter, Hanny Al-Samkari, James Bussel, Filip Matthijssens, Anna Hultberg, Jaume Ayguasanosa Dachs, Kristof De Beuf, Francesco Rodeghiero, Marc Michel, Adrian Newland
Publikováno v:
HemaSphere, Vol 7, p e02996d3 (2023)
Externí odkaz:
https://doaj.org/article/ec588614d5f4449cb0dc895160e3537b
Autor:
Thomas Pabst, Norbert Vey, Lionel Adès, Ulrike Bacher, Mario Bargetzi, Samson Fung, Gianluca Gaidano, Domenica Gandini, Anna Hultberg, Amy Johnson, Xuewen Ma, Rouven Müller, Kerri Nottage, Cristina Papayannidis, Christian Recher, Carsten Riether, Priya Shah, Jeffrey Tryon, Liang Xiu, Adrian F. Ochsenbein
Publikováno v:
Haematologica, Vol 108, Iss 7 (2023)
Cusatuzumab is a high-affinity, anti-CD70 monoclonal antibody under investigation in acute myeloid leukemia (AML). This two-part, open-label, multicenter, phase I/II trial evaluated cusatuzumab plus azacitidine in patients with newly diagnosed AML in
Externí odkaz:
https://doaj.org/article/44a72b022e1b4366bad1fca7a93513e4
Autor:
Philippe Aftimos, Christian Rolfo, Sylvie Rottey, Philippe Barthélémy, Christophe Borg, Keunchil Park, Do-Youn Oh, Sang-We Kim, Natalie De Jonge, Valérie Hanssens, Karen Zwanenpoel, Carla Molthoff, Daniëlle Vugts, Torsten Dreier, Peter Verheesen, Guus A.M.S. van Dongen, Julie Jacobs, Luc Van Rompaey, Anna Hultberg, Paolo Michieli, Patrick Pauwels, Samson Fung, Alain Thibault, Hans de Haard, Nicolas Leupin, Ahmad Awada
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 665 (2021)
Dysregulation of MET signaling has been implicated in tumorigenesis and metastasis. ARGX-111 combines complete blockade of this pathway with enhanced tumor cell killing and was investigated in 24 patients with MET-positive advanced cancers in a phase
Externí odkaz:
https://doaj.org/article/f221f0cc086e421e96736936b19db3e0
Autor:
Ahmad Awada, Nicolas Leupin, Alain Thibault, Marc Peeters, Vincent Ribrag, Hans de Haard, Domenica Gandini, Anna Hultberg, Karen Silence, Jean-Marie Michot, Luc Van Rompaey, Torsten Dreier, Mahan Moshir, Jean-Charles Soria, Marie Maerevoet, Dominique Bron, Fritz Offner, Sylvie Rottey, Christian Rolfo, Philippe Aftimos
Purpose: The purpose of this study was to evaluate safety, pharmacokinetics, pharmacodynamics, and preliminary antitumor efficacy of ARGX-110, a glyco-engineered monoclonal antibody, targeting CD70, in patients with CD70 expressing advanced malignanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f67c8aed5e69084842277494b50f36b
https://doi.org/10.1158/1078-0432.c.6527006.v1
https://doi.org/10.1158/1078-0432.c.6527006.v1
Autor:
Ahmad Awada, Nicolas Leupin, Alain Thibault, Marc Peeters, Vincent Ribrag, Hans de Haard, Domenica Gandini, Anna Hultberg, Karen Silence, Jean-Marie Michot, Luc Van Rompaey, Torsten Dreier, Mahan Moshir, Jean-Charles Soria, Marie Maerevoet, Dominique Bron, Fritz Offner, Sylvie Rottey, Christian Rolfo, Philippe Aftimos
More details about inclusion and exclusion criteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4ba8d81175c304fee0f68912d285fb
https://doi.org/10.1158/1078-0432.22468604
https://doi.org/10.1158/1078-0432.22468604
Autor:
Paolo Michieli, Hans de Haard, Torsten Dreier, Alain Thibault, Michael Saunders, Peter Brouckaert, Flavio Maina, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Fabienne Lamballe, Benjamin Roux, Raimond Heukers, Els Festjens, Karen Silence, Gitte De Boeck, Valérie Hanssens, Christophe Blanchetot, Natalie De Jonge, Leander Huyghe, Virginia Morello, Anna Hultberg
Supplementary Figures S1-S7. WT52 inhibits both HGF-dependent and -independent MET autophosphorylation (S1); MET-targeted ADCC prevents tumor recurrence and suppresses metastatic dissemination in an adjuvant orthotopic model of mammary carcinoma (S2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18e075a4cdf87c1e3380cb4bd731bf0
https://doi.org/10.1158/0008-5472.22406322.v1
https://doi.org/10.1158/0008-5472.22406322.v1
Autor:
Paolo Michieli, Hans de Haard, Torsten Dreier, Alain Thibault, Michael Saunders, Peter Brouckaert, Flavio Maina, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Fabienne Lamballe, Benjamin Roux, Raimond Heukers, Els Festjens, Karen Silence, Gitte De Boeck, Valérie Hanssens, Christophe Blanchetot, Natalie De Jonge, Leander Huyghe, Virginia Morello, Anna Hultberg
Hepatocyte growth factor (HGF) and its receptor MET represent validated targets for cancer therapy. However, HGF/MET inhibitors being explored as cancer therapeutics exhibit cytostatic activity rather than cytotoxic activity, which would be more desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72807272b6bf8be1075b6f07eeff9a65
https://doi.org/10.1158/0008-5472.c.6507042.v1
https://doi.org/10.1158/0008-5472.c.6507042.v1
Autor:
Paolo Michieli, Hans de Haard, Torsten Dreier, Alain Thibault, Michael Saunders, Peter Brouckaert, Flavio Maina, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Fabienne Lamballe, Benjamin Roux, Raimond Heukers, Els Festjens, Karen Silence, Gitte De Boeck, Valérie Hanssens, Christophe Blanchetot, Natalie De Jonge, Leander Huyghe, Virginia Morello, Anna Hultberg
Supplementary Tables S1-S7. Binding of WT52, WT52-E and WT52-D to human and mouse Fc gamma receptors (S1); ADCC activity of engineered antibodies (S2); In vitro characterization of the germlined G52 antibody (S3); Binding of G52 and ARGX-111 to human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd857487f04091ada111625ba04fad4
https://doi.org/10.1158/0008-5472.22406316
https://doi.org/10.1158/0008-5472.22406316
Autor:
Paolo Michieli, Hans de Haard, Torsten Dreier, Alain Thibault, Michael Saunders, Peter Brouckaert, Flavio Maina, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Fabienne Lamballe, Benjamin Roux, Raimond Heukers, Els Festjens, Karen Silence, Gitte De Boeck, Valérie Hanssens, Christophe Blanchetot, Natalie De Jonge, Leander Huyghe, Virginia Morello, Anna Hultberg
Supplementary Methods and References. Description of additional methods and procedures used in the study. Also includes Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6565d44a59a176be702ec7d00f10864f
https://doi.org/10.1158/0008-5472.22406319.v1
https://doi.org/10.1158/0008-5472.22406319.v1
Autor:
Sanne Terryn, Aurélie Francart, Sophie Lamoral, Anna Hultberg, Heidi Rommelaere, Angela Wittelsberger, Filip Callewaert, Thomas Stohr, Kris Meerschaert, Ingrid Ottevaere, Catelijne Stortelers, Peter Vanlandschoot, Michael Kalai, Steven Van Gucht
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109367 (2014)
Rabies virus causes lethal brain infection in about 61000 people per year. Each year, tens of thousands of people receive anti-rabies prophylaxis with plasma-derived immunoglobulins and vaccine soon after exposure. Anti-rabies immunoglobulins are how
Externí odkaz:
https://doaj.org/article/f73ce9c0c0a04bf6ab81b08828be58b4