Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anna, Gorelik"'
Autor:
Aditya Kshirsagar, Svetlana Maslov Doroshev, Anna Gorelik, Tsviya Olender, Tamar Sapir, Daisuke Tsuboi, Irit Rosenhek-Goldian, Sergey Malitsky, Maxim Itkin, Amir Argoetti, Yael Mandel-Gutfreund, Sidney R. Cohen, Jacob H. Hanna, Igor Ulitsky, Kozo Kaibuchi, Orly Reiner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Lissencephaly-1 (LIS1) is associated with neurodevelopmental diseases and is known to regulate the molecular motor cytoplasmic dynein activity. Here we show that LIS1 is essential for the viability of mouse embryonic stem cells (mESCs), and
Externí odkaz:
https://doaj.org/article/8c6fab3847b84597928e2c033a4023c9
Autor:
Tamar Sapir, Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Ziv Porat, Ingrid E. Scheffer, David B. Goldstein, Orrin Devinsky, Orly Reiner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
HNRNPU is an RNA splicing protein associated with brain disorders such as early onset seizures. Here they show that HNRNPU functions to maintain neural progenitors and their progeny by regulating splicing of key neuronal genes.
Externí odkaz:
https://doaj.org/article/b79fbbfd33ea4996851afbb74dc44821
Autor:
Anna Gorelik, Tamar Sapir, Rebecca Haffner-Krausz, Tsviya Olender, Trent M. Woodruff, Orly Reiner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Emerging evidence suggests that immune molecules play an important role in regulating brain development. Goreliket al. show that molecules in the lectin arm of the complement pathway are expressed in the developing mouse cortex, and regulate radial m
Externí odkaz:
https://doaj.org/article/e11dc61947534819a52c2923baf9b313
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The complement system, which is part of the innate immune response system, has been recently shown to participate in multiple key processes in the developing brain. Here we aimed to elucidate downstream signaling responses linking complement C3, a ke
Externí odkaz:
https://doaj.org/article/b2f62db56d484db796c388beb6b4eec2
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Current knowledge regarding regulation of radial neuronal migration is mainly focused on intracellular molecules. Our unbiased screen aimed at identification of non-cell autonomous mechanisms involved in this process detected differential expression
Externí odkaz:
https://doaj.org/article/82d4f305be38496f937accfa2ccdb543
Autor:
Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Tamar Sapir, Daisuke Tsuboi, Irit Rosenhek-Goldian, Sergey Malitsky, Maxim Itkin, Amir Argoetti, Yael Mandel-Gutfreund, Sidney R. Cohen, Jacob Hanna, Igor Ulitsky, Kozo Kaibuchi, Orly Reiner
Lissencephaly-1 (LIS1) is associated with neurodevelopmental diseases and is known to regulate the activity of the molecular motor cytoplasmic dynein. Here we show that LIS1 is essential for the viability of mouse embryonic stem cells (mESCs), and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fce476746ff1b7115500a216e83be622
https://doi.org/10.1101/2022.03.08.483407
https://doi.org/10.1101/2022.03.08.483407
Autor:
Louis Mudannayake, Parag Mehta, Gregory Goldenberg, Anna Gorelik, Arundati Ramesh, Nga Yu Cheung, Thayyllathil Bharathan
Publikováno v:
Journal of Multidisciplinary Healthcare. 12:437-443
Background: With growing expense in chronic illness and end-of-life (EOL) care, population-based interventions are needed to reduce the health care cost and improve patients’ quality of life. The authors believe that promotion of palliative medicin
Autor:
Nga Yu, Cheung, Anna, Gorelik, Parag, Mehta, Louis, Mudannayake, Arundati, Ramesh, Thayyllathil, Bharathan, Gregory, Goldenberg
Publikováno v:
Journal of Multidisciplinary Healthcare
Background: With growing expense in chronic illness and end-of-life (EOL) care, population-based interventions are needed to reduce the health care cost and improve patients’ quality of life. The authors believe that promotion of palliative medicin
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
The complement system, which is part of the innate immune response system, has been recently shown to participate in multiple key processes in the developing brain. Here we aimed to elucidate downstream signaling responses linking complement C3, a ke
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Current knowledge regarding regulation of radial neuronal migration is mainly focused on intracellular molecules. Our unbiased screen aimed at identification of non-cell autonomous mechanisms involved in this process detected differential expression