Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Anna, Dimberg"'
Autor:
Tina Sarén, Giulia Saronio, Paula Marti Torrell, Xu Zhu, Josefin Thelander, Yasmin Andersson, Camilla Hofström, Marika Nestor, Anna Dimberg, Helena Persson, Mohanraj Ramachandran, Di Yu, Magnus Essand
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Chimeric antigen receptor (CAR)-T cell therapy is rapidly advancing as cancer treatment, however, designing an optimal CAR remains challenging. A single-chain variable fragment (scFv) is generally used as CAR targeting moiety, wherein the co
Externí odkaz:
https://doaj.org/article/c97dd91fb4d34f1e8111dd6c28476906
Autor:
Elin Sjöberg, Marit Melssen, Mark Richards, Yindi Ding, Catarina Chanoca, Dongying Chen, Emmanuel Nwadozi, Sagnik Pal, Dominic T. Love, Takeshi Ninchoji, Masabumi Shibuya, Michael Simons, Anna Dimberg, Lena Claesson-Welsh
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
Endothelial phospholipase Cγ (PLCγ) is essential for vascular development; however, its role in healthy, mature, or pathological vessels is unexplored. Here, we show that PLCγ was prominently expressed in vessels of several human cancer forms, not
Externí odkaz:
https://doaj.org/article/7698f966a69a496bb790494d6f6061b0
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tertiary lymphoid structures (TLS) are lymph node-like aggregates that can form in association with chronic inflammation or cancer. Mature TLS are organized into B and T cell zones, and are not encapsulated but include all cell types necessary for el
Externí odkaz:
https://doaj.org/article/bd5ff71ca3964590bb3ec6357e6c95ad
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/b929f0fbf9bf4251bd6018f5670e22eb
Autor:
Doroteya Raykova, Despoina Kermpatsou, Tony Malmqvist, Philip J. Harrison, Marie Rubin Sander, Christiane Stiller, Johan Heldin, Mattias Leino, Sara Ricardo, Anna Klemm, Leonor David, Ola Spjuth, Kalyani Vemuri, Anna Dimberg, Anders Sundqvist, Maria Norlin, Axel Klaesson, Caroline Kampf, Ola Söderberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract Determining the levels of protein–protein interactions is essential for the analysis of signaling within the cell, characterization of mutation effects, protein function and activation in health and disease, among others. Herein, we descri
Externí odkaz:
https://doaj.org/article/62ebc0c6a0da437aba3d465a5bbe05c2
Autor:
Doroteya Raykova, Despoina Kermpatsou, Tony Malmqvist, Philip J. Harrison, Marie Rubin Sander, Christiane Stiller, Johan Heldin, Mattias Leino, Sara Ricardo, Anna Klemm, Leonor David, Ola Spjuth, Kalyani Vemuri, Anna Dimberg, Anders Sundqvist, Maria Norlin, Axel Klaesson, Caroline Kampf, Ola Söderberg
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/1b52ed4d7464442c978e7ac4bff1d6a2
Autor:
Luuk van Hooren, Alessandra Vaccaro, Mohanraj Ramachandran, Konstantinos Vazaios, Sylwia Libard, Tiarne van de Walle, Maria Georganaki, Hua Huang, Ilkka Pietilä, Joey Lau, Maria H. Ulvmar, Mikael C. I. Karlsson, Maria Zetterling, Sara M. Mangsbo, Asgeir S. Jakola, Thomas Olsson Bontell, Anja Smits, Magnus Essand, Anna Dimberg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Agonistic CD40 antibodies (αCD40) have broad immunostimulatory properties, however their efficacy in glioma remains unclear. Here the authors show that αCD40 promotes the formation of tertiary lymphoid structures but does not improve survival and i
Externí odkaz:
https://doaj.org/article/960c23767579410eb75556847b8c9b3f
Autor:
Miika Martikainen, Mohanraj Ramachandran, Roberta Lugano, Jing Ma, Minttu-Maria Martikainen, Anna Dimberg, Di Yu, Andres Merits, Magnus Essand
Publikováno v:
Molecular Therapy: Oncolytics, Vol 21, Iss , Pp 37-46 (2021)
Oncolytic virotherapy holds promise of effective immunotherapy against otherwise nonresponsive cancers such as glioblastoma. Our previous findings have shown that although oncolytic Semliki Forest virus (SFV) is effective against various mouse gliobl
Externí odkaz:
https://doaj.org/article/d21025b7887f4306ad9176f77d4f49d9
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/ad5bb212aa024ffc82dcc33d26ccca85
Tumor endothelial ELTD1 as a predictive marker for treatment of renal cancer patients with sunitinib
Autor:
Marjut Niinivirta, Maria Georganaki, Gunilla Enblad, Cecilia Lindskog, Anna Dimberg, Gustav J. Ullenhag
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Patients with metastatic renal cell cancer (mRCC) are commonly treated with the tyrosine kinase inhibitor sunitinib, which blocks signalling from vascular endothelial growth factor (VEGF) - and platelet-derived growth factor-recep
Externí odkaz:
https://doaj.org/article/0748aaf10fc64588805e2ac5a8b8518a