Exploring the sequence diversity and surface expression of Factor H-Binding Protein among invasive serogroup B meningococcal strains from selected European countries

Autor: Stephen A. Clark, Laura Willerton, Heike Claus, Anna Carannante, Paola Stefanelli, Raquel Abad, Julio A. Vázquez, Ray Borrow

Publikováno v: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

Factor H-Binding Protein (fHbp) is a key component of meningococcal vaccines such as MenB-fHbp, licensed in the EU, UK, and other countries. Sufficient expression of fHbp on the bacterial surface is necessary for vaccine-induced antibodies to bind an

Externí odkaz: https://doaj.org/article/30d17cfe85f54ef29e8244af63d98a81

FHbp variants among meningococci of serogroup B in Italy: Evolution and selective pressure, 2014–2017

Autor: Alessandra Lo Presti, Anna Carannante, Cecilia Fazio, Arianna Neri, Paola Vacca, Luigina Ambrosio, Florigio Lista, Silvia Fillo, Paola Stefanelli

Publikováno v: PLoS ONE, Vol 18, Iss 2 (2023)

Background Neisseria meningitidis (meningococcus) is the causative agent of invasive meningococcal disease (IMD). Meningococcus of serogroup B (MenB) is one of the main serogroup causing IMD. MenB strains may be prevented by meningococcal B vaccines.

Externí odkaz: https://doaj.org/article/95c6e46074ed4ade917fd7d5fcfed64c

Evaluation of Meningococcal Serogroup C Bactericidal Antibodies after Primary Vaccination: A Multicentre Study, Italy

Autor: Arianna Neri, Massimo Fabiani, Anna Maria Barbui, Caterina Vocale, Alessandro Miglietta, Cecilia Fazio, Anna Carannante, Annapina Palmieri, Paola Vacca, Luigina Ambrosio, Paola Stefanelli

Publikováno v: Vaccines, Vol 10, Iss 5, p 778 (2022)

Here, we evaluated over time in different cohorts of children vaccinated against serogroup C Neisseria meningitidis, the presence of antibodies with neutralizing activity. A total of 348 sera samples of enrolled children by year since vaccination (p

Externí odkaz: https://doaj.org/article/2ae1e78dc4d4477e879b2a743d30fbbf

Europe-wide expansion and eradication of multidrug-resistant Neisseria gonorrhoeae lineages: a genomic surveillance study

Autor: Leonor Sánchez-Busó, Michelle J Cole, Gianfranco Spiteri, Michaela Day, Susanne Jacobsson, Daniel Golparian, Noshin Sajedi, Corin A Yeats, Khalil Abudahab, Anthony Underwood, Benjamin Bluemel, David M Aanensen, Magnus Unemo, Sonja Pleininger, Alexander Indra, Irith De Baetselier, Wim Vanden Berghe, Blaženka Hunjak, Tatjana Nemeth Blažić, Panayiota Maikanti-Charalambous, Despo Pieridou, Hana Zákoucká, Helena Žemličková, Steen Hoffmann, Susan Cowan, Lasse Jessen Schwartz, Rita Peetso, Jevgenia Epstein, Jelena Viktorova, Ndeindo Ndeikoundam, Beatrice Bercot, Cécile Bébéar, Florence Lot, Susanne Buder, Klaus Jansen, Vivi Miriagou, Georgios Rigakos, Vasilios Raftopoulos, Eszter Balla, Mária Dudás, Lena Rós Ásmundsdóttir, Guðrún Sigmundsdóttir, Guðrún Svanborg Hauksdóttir, Thorolfur Gudnason, Aoife Colgan, Brendan Crowley, Sinéad Saab, Paola Stefanelli, Anna Carannante, Patrizia Parodi, Gatis Pakarna, Raina Nikiforova, Antra Bormane, Elina Dimina, Monique Perrin, Tamir Abdelrahman, Joël Mossong, Jean-Claude Schmit, Friedrich Mühlschlegel, Christopher Barbara, Francesca Mifsud, Alje Van Dam, Birgit Van Benthem, Maartje Visser, Ineke Linde, Hilde Kløvstad, Dominique Caugant, Beata Młynarczyk-Bonikowska, Jacinta Azevedo, Maria-José Borrego, Marina Lurdes Ramos Nascimento, Peter Pavlik, Irena Klavs, Andreja Murnik, Samo Jeverica, Tanja Kustec, Julio Vázquez Moreno, Asuncion Diaz, Raquel Abad, Inga Velicko, Helen Fifer, Jill Shepherd, Lynsey Patterson

Publikováno v: The Lancet. Microbe, 3(6), e452-e463. Elsevier Ltd

Centre for Genomic Pathogen Surveillance and the Euro-GASP study group: Sonja Pleininger, Alexander Indra, Irith De Baetselier, Wim Vanden Berghe, Blaženka Hunjak, Tatjana Nemeth Blažić, Panayiota Maikanti-Charalambous, Despo Pieridou, Hana Zákou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96eb79a577cd7d54a833a9866213f5e6
https://doi.org/10.1016/s2666-5247(22)00044-1

Time trend analysis (2009-2016) of antimicrobial susceptibility in Neisseria gonorrhoeae isolated in Italy following the introduction of the combined antimicrobial therapy.

Autor: Paola Stefanelli, Maria Fenicia Vescio, Maria Paola Landini, Ivano Dal Conte, Alberto Matteelli, Antonio Cristaudo, Marina Gaino, Marco Cusini, Anna Maria Barbui, Antonella Mencacci, Rosella De Nittis, Valeria Ghisetti, Elena Stroppiana, Anna Carannante, Neisseria gonorrhoeae antimicrobials resistant Study Group

Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189484 (2017)

Neisseria gonorrhoeae (NG) antimicrobial susceptibility trends to azithromycin, cefixime and ceftriaxone were analyzed, from 2009 to 2016, to monitor changing antimicrobial susceptibility concomitant with the change in prescribing practice in 2012 fr

Externí odkaz: https://doaj.org/article/9452bcc04ff34f0eb805194c54d04e88